Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 ABAT 💬 [6] Alanine, aspartate and glutamate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism, Butanoate metabolism, GABAergic synapse Valproate sodium 💬 Valproic acid [13] 2, 3, 5, 6, 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
2 ABAT 💬 [6] Alanine, aspartate and glutamate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism, Butanoate metabolism, GABAergic synapse Vigabatrin 💬 Vigabatrin [2] 145, 158 💬
3 ABAT 💬 [6] Alanine, aspartate and glutamate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism, Butanoate metabolism, GABAergic synapse Divalproex sodium 💬 Valproic acid [13] 2, 3, 5, 6, 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
4 ABAT 💬 [6] Alanine, aspartate and glutamate metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism, Butanoate metabolism, GABAergic synapse Valproic acid 💬 Valproic acid [13] 2, 3, 5, 6, 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
5 ACHE 💬 [3] Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Neostigmine 💬 Neostigmine [1] 11 💬
6 ACHE 💬 [3] Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Rivastigmine 💬 Rivastigmine [3] 5, 6, 13 💬
7 ACHE 💬 [3] Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Latrepirdine 💬 Latrepirdine [1] 8 💬
8 ACHE 💬 [3] Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Galantamine 💬 Galantamine [3] 6, 11, 127 💬
9 ACHE 💬 [3] Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Neostigmine bromide 💬 Neostigmine [1] 11 💬
10 ACHE 💬 [3] Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Tacrine 💬 Tacrine [2] 46, 271 💬
11 ACHE 💬 [3] Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Donepezil 💬 Donepezil [8] 5, 6, 13, 46, 124, 127, 156, 206 💬
12 ACHE 💬 [3] Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Pyridostigmine bromide 💬 Pyridostigmine [5] 3, 6, 11, 51, 256 💬
13 ACHE 💬 [3] Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Neostigmine methylsulfate 💬
(Neostigmine methylsulfate)		 Neostigmine [1] 11 💬
14 ACHE 💬 [3] Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Galantamine hydrobromide 💬 Galantamine [3] 6, 11, 127 💬
15 ACHE 💬 [3] Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Latrepirdine dihydrochloride 💬 Latrepirdine [1] 8 💬
16 ACHE 💬 [3] Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Rivastigmine tartrate 💬 Rivastigmine [3] 5, 6, 13 💬
17 ACHE 💬 [3] Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Tacrine hydrochloride 💬 Tacrine [2] 46, 271 💬
18 ACHE 💬 [3] Glycerophospholipid metabolism, Neuroactive ligand signaling, Cholinergic synapse Donepezil hydrochloride 💬 Donepezil [8] 5, 6, 13, 46, 124, 127, 156, 206 💬
19 ADA 💬 [2] Purine metabolism, Primary immunodeficiency Pentostatin 💬 Pentostatin [1] 60 💬
20 ADA 💬 [2] Purine metabolism, Primary immunodeficiency Elapegademase 💬 Elapegademase [1] 65 💬
21 ADAM17 💬
(Full name: ADAM metallopeptidase domain 17)		[6] Efferocytosis, Notch signaling pathway, TNF signaling pathway, Alzheimer disease, Epithelial cell signaling in Helicobacter pylori infection, Coronavirus disease - COVID-19 Apratastat 💬 Apratastat [1] 46 💬
22 ADAMTS13 💬
(Full name: ADAM metallopeptidase with thrombospondin type 1 motif 13)		[1] Platelet activation Apadamtase alfa and cinaxadamtase alfa 💬 Apadamtase alfa [1] 64 💬
23 ADAMTS13 💬
(Full name: ADAM metallopeptidase with thrombospondin type 1 motif 13)		[1] Platelet activation Apadamtase alfa 💬 Apadamtase alfa [1] 64 💬
24 ADH1A 💬 [8] Glycolysis / Gluconeogenesis, Fatty acid degradation, Tyrosine metabolism, Pyruvate metabolism, Retinol metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450, Alcoholic liver disease Fomepizole 💬 Fomepizole [1] 301 💬
25 ADH1B 💬 [8] Glycolysis / Gluconeogenesis, Fatty acid degradation, Tyrosine metabolism, Pyruvate metabolism, Retinol metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450, Alcoholic liver disease Fomepizole 💬 Fomepizole [1] 301 💬
26 ADH1C 💬 [8] Glycolysis / Gluconeogenesis, Fatty acid degradation, Tyrosine metabolism, Pyruvate metabolism, Retinol metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450, Alcoholic liver disease Fomepizole 💬 Fomepizole [1] 301 💬
27 AKR1B1 💬 [5] Pentose and glucuronate interconversions, Fructose and mannose metabolism, Galactose metabolism, Glycerolipid metabolism, Folate biosynthesis Epalrestat 💬 Epalrestat [1] 10 💬
28 ALAS1 💬 [2] Glycine, serine and threonine metabolism, Porphyrin metabolism Hemin 💬 Hemin [1] 254 💬
29 ALAS1 💬 [2] Glycine, serine and threonine metabolism, Porphyrin metabolism Givosiran 💬 Givosiran [1] 254 💬
30 ALAS1 💬 [2] Glycine, serine and threonine metabolism, Porphyrin metabolism Givosiran sodium 💬 Givosiran [1] 254 💬
31 ALAS2 💬 [2] Glycine, serine and threonine metabolism, Porphyrin metabolism Hemin 💬 Hemin [1] 254 💬
32 ALDH5A1 💬 [2] Alanine, aspartate and glutamate metabolism, Butanoate metabolism Valproic acid 💬 Valproic acid [13] 2, 3, 5, 6, 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
33 ALDH5A1 💬 [2] Alanine, aspartate and glutamate metabolism, Butanoate metabolism Divalproex sodium 💬 Valproic acid [13] 2, 3, 5, 6, 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
34 ALDH5A1 💬 [2] Alanine, aspartate and glutamate metabolism, Butanoate metabolism Valproate sodium 💬 Valproic acid [13] 2, 3, 5, 6, 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
35 ALOX15 💬 [6] Arachidonic acid metabolism, Linoleic acid metabolism, Efferocytosis, Ferroptosis, Necroptosis, Serotonergic synapse Utreloxastat 💬 Utreloxastat [1] 2 💬
36 ALOX5 💬 [6] Arachidonic acid metabolism, Efferocytosis, Fc epsilon RI signaling pathway, Serotonergic synapse, Ovarian steroidogenesis, Toxoplasmosis Oxatomide 💬 Oxatomide [1] 113 💬
37 ALOX5 💬 [6] Arachidonic acid metabolism, Efferocytosis, Fc epsilon RI signaling pathway, Serotonergic synapse, Ovarian steroidogenesis, Toxoplasmosis Zileuton 💬 Zileuton [3] 85, 160, 164 💬
38 ALPI 💬 [2] Thiamine metabolism, Folate biosynthesis Ilofotase alfa 💬 Recombinant human alkaline phosphatase [1] 172 💬
39 ALPL 💬 [2] Thiamine metabolism, Folate biosynthesis Asfotase alfa 💬 Asfotase alfa [1] 172 💬
40 AMY2A 💬 [4] Starch and sucrose metabolism, Salivary secretion, Pancreatic secretion, Carbohydrate digestion and absorption Acarbose 💬 Acarbose [1] 298 💬
41 AMY2B 💬 [4] Starch and sucrose metabolism, Salivary secretion, Pancreatic secretion, Carbohydrate digestion and absorption Acarbose 💬 Acarbose [1] 298 💬
42 ANGPTL3 💬 [1] Cholesterol metabolism Evinacumab 💬 Evinacumab [1] 79 💬
43 ANPEP 💬 [3] Glutathione metabolism, Renin-angiotensin system, Hematopoietic cell lineage Ubenimex 💬 Ubenimex [1] 86 💬
44 AOC3 💬 [4] Glycine, serine and threonine metabolism, Tyrosine metabolism, Phenylalanine metabolism, beta-Alanine metabolism Hydralazine 💬 Hydralazine [1] 67 💬
45 APOB 💬 [4] Fat digestion and absorption, Vitamin digestion and absorption, Cholesterol metabolism, Lipid and atherosclerosis Mipomersen sodium 💬 Mipomersen [1] 79 💬
46 APOC3 💬 [2] PPAR signaling pathway, Cholesterol metabolism Volanesorsen 💬 Volanesorsen [1] 265 💬
47 APOC3 💬 [2] PPAR signaling pathway, Cholesterol metabolism Volanesorsen sodium 💬 Volanesorsen [1] 265 💬
48 CA1 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
49 CA1 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
50 CA1 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
51 CA1 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
52 CA1 💬 [1] Nitrogen metabolism Dichlorphenamide 💬 Diclofenamide [1] 114 💬
53 CA12 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
54 CA12 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
55 CA12 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
56 CA12 💬 [1] Nitrogen metabolism Dichlorphenamide 💬 Diclofenamide [1] 114 💬
57 CA12 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
58 CA13 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
59 CA13 💬 [1] Nitrogen metabolism Dichlorphenamide 💬 Diclofenamide [1] 114 💬
60 CA13 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
61 CA13 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
62 CA13 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
63 CA14 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
64 CA14 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
65 CA14 💬 [1] Nitrogen metabolism Dichlorphenamide 💬 Diclofenamide [1] 114 💬
66 CA14 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
67 CA14 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
68 CA2 💬 [6] Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Dichlorphenamide 💬 Diclofenamide [1] 114 💬
69 CA2 💬 [6] Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
70 CA2 💬 [6] Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Acetazolamide 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
71 CA2 💬 [6] Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Acetazolamide sodium 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
72 CA2 💬 [6] Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Topiramate 💬 Topiramate [5] 6, 140, 144, 156, 193 💬
73 CA2 💬 [6] Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion, Bile secretion Dorzolamide 💬 Dorzolamide [1] 90 💬
74 CA3 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
75 CA3 💬 [1] Nitrogen metabolism Dichlorphenamide 💬 Diclofenamide [1] 114 💬
76 CA3 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
77 CA3 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
78 CA3 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
79 CA4 💬 [2] Nitrogen metabolism, Proximal tubule bicarbonate reclamation Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
80 CA4 💬 [2] Nitrogen metabolism, Proximal tubule bicarbonate reclamation Topiramate 💬 Topiramate [5] 6, 140, 144, 156, 193 💬
81 CA4 💬 [2] Nitrogen metabolism, Proximal tubule bicarbonate reclamation Dichlorphenamide 💬 Diclofenamide [1] 114 💬
82 CA4 💬 [2] Nitrogen metabolism, Proximal tubule bicarbonate reclamation Dorzolamide 💬 Dorzolamide [1] 90 💬
83 CA4 💬 [2] Nitrogen metabolism, Proximal tubule bicarbonate reclamation Acetazolamide 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
84 CA4 💬 [2] Nitrogen metabolism, Proximal tubule bicarbonate reclamation Acetazolamide sodium 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
85 CA5A 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
86 CA5A 💬 [1] Nitrogen metabolism Dichlorphenamide 💬 Diclofenamide [1] 114 💬
87 CA5A 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
88 CA5A 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
89 CA5A 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
90 CA5B 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
91 CA5B 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
92 CA5B 💬 [1] Nitrogen metabolism Dichlorphenamide 💬 Diclofenamide [1] 114 💬
93 CA5B 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
94 CA5B 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
95 CA6 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
96 CA6 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
97 CA6 💬 [1] Nitrogen metabolism Dichlorphenamide 💬 Diclofenamide [1] 114 💬
98 CA6 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
99 CA6 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
100 CA7 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
101 CA7 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
102 CA7 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
103 CA7 💬 [1] Nitrogen metabolism Dichlorphenamide 💬 Diclofenamide [1] 114 💬
104 CA7 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
105 CA8 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
106 CA8 💬 [1] Nitrogen metabolism Dichlorphenamide 💬 Diclofenamide [1] 114 💬
107 CA8 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
108 CA8 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
109 CA8 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
110 CA9 💬 [1] Nitrogen metabolism Acetazolamide sodium 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
111 CA9 💬 [1] Nitrogen metabolism Dorzolamide 💬 Dorzolamide [1] 90 💬
112 CA9 💬 [1] Nitrogen metabolism Acetazolamide 💬 Acetazolamide [6] 13, 90, 115, 155, 225, 230 💬
113 CA9 💬 [1] Nitrogen metabolism Dorzolamide hydrochloride 💬 Dorzolamide [1] 90 💬
114 CA9 💬 [1] Nitrogen metabolism Dichlorphenamide 💬 Diclofenamide [1] 114 💬
115 CBS 💬 [3] Glycine, serine and threonine metabolism, Cysteine and methionine metabolism, One carbon pool by folate Pegtibatinase 💬 Pegtibatinase [1] 337 💬
116 CD38 💬 [6] Nicotinate and nicotinamide metabolism, Calcium signaling pathway, Hematopoietic cell lineage, Oxytocin signaling pathway, Salivary secretion, Pancreatic secretion Isatuximab 💬 Isatuximab [3] 28, 61, 283 💬
117 CD38 💬 [6] Nicotinate and nicotinamide metabolism, Calcium signaling pathway, Hematopoietic cell lineage, Oxytocin signaling pathway, Salivary secretion, Pancreatic secretion Mezagitamab 💬 Mezagitamab [2] 63, 66 💬
118 CD38 💬 [6] Nicotinate and nicotinamide metabolism, Calcium signaling pathway, Hematopoietic cell lineage, Oxytocin signaling pathway, Salivary secretion, Pancreatic secretion Ciltacabtagene autoleucel 💬 Ciltacabtagene autoleucel [1] 28 💬
119 CD38 💬 [6] Nicotinate and nicotinamide metabolism, Calcium signaling pathway, Hematopoietic cell lineage, Oxytocin signaling pathway, Salivary secretion, Pancreatic secretion Daratumumab 💬 Daratumumab [10] 13, 16, 28, 46, 48, 49, 60, 63, 288, 331 💬
120 CETP 💬 [1] Cholesterol metabolism Anacetrapib 💬 Anacetrapib [1] 79 💬
121 CETP 💬 [1] Cholesterol metabolism Torcetrapib 💬 Torcetrapib [1] 79 💬
122 COMT 💬
(Full name: catechol-O-methyltransferase)		[3] Steroid hormone biosynthesis, Tyrosine metabolism, Dopaminergic synapse Opicapone 💬 Opicapone [1] 6 💬
123 COMT 💬
(Full name: catechol-O-methyltransferase)		[3] Steroid hormone biosynthesis, Tyrosine metabolism, Dopaminergic synapse Tolcapone 💬 Tolcapone [3] 6, 28, 127 💬
124 COMT 💬
(Full name: catechol-O-methyltransferase)		[3] Steroid hormone biosynthesis, Tyrosine metabolism, Dopaminergic synapse Entacapone 💬 Entacapone [2] 6, 17 💬
125 CPS1 💬 [3] Arginine biosynthesis, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism Carglumic acid 💬 Carglumic acid [3] 245, 246, 251 💬
126 DDC 💬 [8] Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Serotonergic synapse, Dopaminergic synapse, Cocaine addiction, Amphetamine addiction, Alcoholism Benserazide hydrochloride 💬 Benserazide [1] 6 💬
127 DDC 💬 [8] Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Serotonergic synapse, Dopaminergic synapse, Cocaine addiction, Amphetamine addiction, Alcoholism Carbidopa 💬 Carbidopa [5] 6, 13, 17, 140, 201 💬
128 DDC 💬 [8] Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Serotonergic synapse, Dopaminergic synapse, Cocaine addiction, Amphetamine addiction, Alcoholism Benserazide 💬 Benserazide [1] 6 💬
129 DHFR 💬 [3] One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate 💬
(Methotrexate)		 Methotrexate [39] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 85, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
130 DHFR 💬 [3] One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate sodium 💬
(Methotrexate sodium, METHOTREXATE)		 Methotrexate [39] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 85, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
131 DHFR2 💬 [3] One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate sodium 💬
(Methotrexate sodium, METHOTREXATE)		 Methotrexate [39] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 85, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
132 DHFR2 💬 [3] One carbon pool by folate, Folate biosynthesis, Folate transport and metabolism Methotrexate 💬
(Methotrexate)		 Methotrexate [39] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 56, 60, 62, 65, 84, 85, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
133 DHODH 💬 [1] Pyrimidine metabolism Teriflunomide 💬 Teriflunomide [4] 13, 25, 26, 63 💬
134 DHODH 💬 [1] Pyrimidine metabolism Vidofludimus calcium 💬 Vidofludimus [5] 13, 46, 94, 96, 97 💬
135 DHODH 💬 [1] Pyrimidine metabolism Leflunomide 💬 Leflunomide [13] 11, 40, 46, 49, 53, 54, 66, 107, 162, 224, 270, 271, 300 💬
136 DHODH 💬 [1] Pyrimidine metabolism Vidofludimus 💬 Vidofludimus [5] 13, 46, 94, 96, 97 💬
137 DNMT1 💬
(Full name: DNA methyltransferase 1)		[2] Cysteine and methionine metabolism, MicroRNAs in cancer Azacitidine 💬 Azacitidine [1] 34 💬
138 DNMT1 💬
(Full name: DNA methyltransferase 1)		[2] Cysteine and methionine metabolism, MicroRNAs in cancer Decitabine 💬 Decitabine [3] 13, 60, 63 💬
139 DNMT3A 💬
(Full name: DNA methyltransferase 3 alpha)		[3] Cysteine and methionine metabolism, Efferocytosis, MicroRNAs in cancer Azacitidine 💬 Azacitidine [1] 34 💬
140 DNMT3A 💬
(Full name: DNA methyltransferase 3 alpha)		[3] Cysteine and methionine metabolism, Efferocytosis, MicroRNAs in cancer Decitabine 💬 Decitabine [3] 13, 60, 63 💬
141 DNMT3B 💬
(Full name: DNA methyltransferase 3 beta)		[2] Cysteine and methionine metabolism, MicroRNAs in cancer Decitabine 💬 Decitabine [3] 13, 60, 63 💬
142 DNMT3B 💬
(Full name: DNA methyltransferase 3 beta)		[2] Cysteine and methionine metabolism, MicroRNAs in cancer Azacitidine 💬 Azacitidine [1] 34 💬
143 EGFR 💬 [47] Virion - Hepatitis viruses, MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Cushing syndrome, Epithelial cell signaling in Helicobacter pylori infection, Shigellosis, Hepatitis C, Human cytomegalovirus infection, Human papillomavirus infection, Coronavirus disease - COVID-19, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Gefitinib 💬 Gefitinib [1] 75 💬
144 EGFR 💬 [47] Virion - Hepatitis viruses, MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Cushing syndrome, Epithelial cell signaling in Helicobacter pylori infection, Shigellosis, Hepatitis C, Human cytomegalovirus infection, Human papillomavirus infection, Coronavirus disease - COVID-19, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Neratinib 💬 Neratinib [1] 34 💬
145 EGFR 💬 [47] Virion - Hepatitis viruses, MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Cushing syndrome, Epithelial cell signaling in Helicobacter pylori infection, Shigellosis, Hepatitis C, Human cytomegalovirus infection, Human papillomavirus infection, Coronavirus disease - COVID-19, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Cetuximab 💬 Cetuximab [5] 34, 51, 86, 89, 331 💬
146 EGFR 💬 [47] Virion - Hepatitis viruses, MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Cushing syndrome, Epithelial cell signaling in Helicobacter pylori infection, Shigellosis, Hepatitis C, Human cytomegalovirus infection, Human papillomavirus infection, Coronavirus disease - COVID-19, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Erlotinib hydrochloride 💬 Erlotinib [2] 94, 160 💬
147 EGFR 💬 [47] Virion - Hepatitis viruses, MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Cushing syndrome, Epithelial cell signaling in Helicobacter pylori infection, Shigellosis, Hepatitis C, Human cytomegalovirus infection, Human papillomavirus infection, Coronavirus disease - COVID-19, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
148 EGFR 💬 [47] Virion - Hepatitis viruses, MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Cushing syndrome, Epithelial cell signaling in Helicobacter pylori infection, Shigellosis, Hepatitis C, Human cytomegalovirus infection, Human papillomavirus infection, Coronavirus disease - COVID-19, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
149 EGFR 💬 [47] Virion - Hepatitis viruses, MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Cushing syndrome, Epithelial cell signaling in Helicobacter pylori infection, Shigellosis, Hepatitis C, Human cytomegalovirus infection, Human papillomavirus infection, Coronavirus disease - COVID-19, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Erlotinib 💬 Erlotinib [2] 94, 160 💬
150 EGFR 💬 [47] Virion - Hepatitis viruses, MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Cushing syndrome, Epithelial cell signaling in Helicobacter pylori infection, Shigellosis, Hepatitis C, Human cytomegalovirus infection, Human papillomavirus infection, Coronavirus disease - COVID-19, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Afatinib dimaleate 💬 Afatinib [1] 285 💬
151 EGFR 💬 [47] Virion - Hepatitis viruses, MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Cushing syndrome, Epithelial cell signaling in Helicobacter pylori infection, Shigellosis, Hepatitis C, Human cytomegalovirus infection, Human papillomavirus infection, Coronavirus disease - COVID-19, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Icotinib 💬 Icotinib [1] 34 💬
152 EGFR 💬 [47] Virion - Hepatitis viruses, MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Cushing syndrome, Epithelial cell signaling in Helicobacter pylori infection, Shigellosis, Hepatitis C, Human cytomegalovirus infection, Human papillomavirus infection, Coronavirus disease - COVID-19, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Tesevatinib 💬 Tesevatinib [1] 67 💬
153 EGFR 💬 [47] Virion - Hepatitis viruses, MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Cushing syndrome, Epithelial cell signaling in Helicobacter pylori infection, Shigellosis, Hepatitis C, Human cytomegalovirus infection, Human papillomavirus infection, Coronavirus disease - COVID-19, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Neratinib maleate 💬 Neratinib [1] 34 💬
154 EGFR 💬 [47] Virion - Hepatitis viruses, MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, GnRH signaling pathway, Estrogen signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, Cushing syndrome, Epithelial cell signaling in Helicobacter pylori infection, Shigellosis, Hepatitis C, Human cytomegalovirus infection, Human papillomavirus infection, Coronavirus disease - COVID-19, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Afatinib 💬 Afatinib [1] 285 💬
155 ENPP2 💬 [1] Ether lipid metabolism Ziritaxestat 💬 Ziritaxestat [2] 51, 85 💬
156 ERBB2 💬 [19] MAPK signaling pathway, ErbB signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Tight junction, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Pancreatic cancer, Endometrial cancer, Prostate cancer, Bladder cancer, Non-small cell lung cancer, Breast cancer, Gastric cancer, Central carbon metabolism in cancer Neratinib maleate 💬 Neratinib [1] 34 💬
157 ERBB2 💬 [19] MAPK signaling pathway, ErbB signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Tight junction, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Pancreatic cancer, Endometrial cancer, Prostate cancer, Bladder cancer, Non-small cell lung cancer, Breast cancer, Gastric cancer, Central carbon metabolism in cancer Lapatinib ditosylate 💬 Lapatinib [3] 34, 74, 75 💬
158 ERBB2 💬 [19] MAPK signaling pathway, ErbB signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Tight junction, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Pancreatic cancer, Endometrial cancer, Prostate cancer, Bladder cancer, Non-small cell lung cancer, Breast cancer, Gastric cancer, Central carbon metabolism in cancer Afatinib dimaleate 💬 Afatinib [1] 285 💬
159 ERBB2 💬 [19] MAPK signaling pathway, ErbB signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Tight junction, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Pancreatic cancer, Endometrial cancer, Prostate cancer, Bladder cancer, Non-small cell lung cancer, Breast cancer, Gastric cancer, Central carbon metabolism in cancer Tesevatinib 💬 Tesevatinib [1] 67 💬
160 ERBB2 💬 [19] MAPK signaling pathway, ErbB signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Tight junction, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Pancreatic cancer, Endometrial cancer, Prostate cancer, Bladder cancer, Non-small cell lung cancer, Breast cancer, Gastric cancer, Central carbon metabolism in cancer Neratinib 💬 Neratinib [1] 34 💬
161 ERBB2 💬 [19] MAPK signaling pathway, ErbB signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Tight junction, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Pancreatic cancer, Endometrial cancer, Prostate cancer, Bladder cancer, Non-small cell lung cancer, Breast cancer, Gastric cancer, Central carbon metabolism in cancer Afatinib 💬 Afatinib [1] 285 💬
162 ERBB2 💬 [19] MAPK signaling pathway, ErbB signaling pathway, Calcium signaling pathway, HIF-1 signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Adherens junction, Tight junction, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Pancreatic cancer, Endometrial cancer, Prostate cancer, Bladder cancer, Non-small cell lung cancer, Breast cancer, Gastric cancer, Central carbon metabolism in cancer Lapatinib 💬 Lapatinib [3] 34, 74, 75 💬
163 FGFR1 💬 [16] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Adherens junction, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Proteoglycans in cancer, Prostate cancer, Melanoma, Breast cancer, Central carbon metabolism in cancer Nintedanib 💬 Nintedanib [7] 51, 84, 85, 89, 227, 228, 331 💬
164 FGFR1 💬 [16] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Adherens junction, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Proteoglycans in cancer, Prostate cancer, Melanoma, Breast cancer, Central carbon metabolism in cancer Nintedanib esylate 💬 Nintedanib [7] 51, 84, 85, 89, 227, 228, 331 💬
165 FGFR1 💬 [16] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Adherens junction, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Proteoglycans in cancer, Prostate cancer, Melanoma, Breast cancer, Central carbon metabolism in cancer Infigratinib phosphate 💬 Infigratinib [1] 276 💬
166 FGFR1 💬 [16] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Adherens junction, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Proteoglycans in cancer, Prostate cancer, Melanoma, Breast cancer, Central carbon metabolism in cancer Infigratinib 💬 Infigratinib [1] 276 💬
167 FGFR1 💬 [16] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Adherens junction, Signaling pathways regulating pluripotency of stem cells, Thermogenesis, Regulation of actin cytoskeleton, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Proteoglycans in cancer, Prostate cancer, Melanoma, Breast cancer, Central carbon metabolism in cancer Catequentinib 💬 Anlotinib [1] 85 💬
168 FGFR2 💬 [12] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer, Gastric cancer, Central carbon metabolism in cancer Catequentinib 💬 Anlotinib [1] 85 💬
169 FGFR2 💬 [12] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer, Gastric cancer, Central carbon metabolism in cancer Palifermin 💬 Palifermin [6] 13, 36, 38, 39, 65, 96 💬
170 FGFR2 💬 [12] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer, Gastric cancer, Central carbon metabolism in cancer Infigratinib 💬 Infigratinib [1] 276 💬
171 FGFR2 💬 [12] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer, Gastric cancer, Central carbon metabolism in cancer Nintedanib esylate 💬 Nintedanib [7] 51, 84, 85, 89, 227, 228, 331 💬
172 FGFR2 💬 [12] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer, Gastric cancer, Central carbon metabolism in cancer Infigratinib phosphate 💬 Infigratinib [1] 276 💬
173 FGFR2 💬 [12] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Pathways in cancer, Prostate cancer, Gastric cancer, Central carbon metabolism in cancer Nintedanib 💬 Nintedanib [7] 51, 84, 85, 89, 227, 228, 331 💬
174 FGFR3 💬 [12] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Pathways in cancer, MicroRNAs in cancer, Bladder cancer, Central carbon metabolism in cancer Nintedanib 💬 Nintedanib [7] 51, 84, 85, 89, 227, 228, 331 💬
175 FGFR3 💬 [12] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Pathways in cancer, MicroRNAs in cancer, Bladder cancer, Central carbon metabolism in cancer Infigratinib 💬 Infigratinib [1] 276 💬
176 FGFR3 💬 [12] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Pathways in cancer, MicroRNAs in cancer, Bladder cancer, Central carbon metabolism in cancer Infigratinib phosphate 💬 Infigratinib [1] 276 💬
177 FGFR3 💬 [12] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Pathways in cancer, MicroRNAs in cancer, Bladder cancer, Central carbon metabolism in cancer Nintedanib esylate 💬 Nintedanib [7] 51, 84, 85, 89, 227, 228, 331 💬
178 FGFR3 💬 [12] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Pathways in cancer, MicroRNAs in cancer, Bladder cancer, Central carbon metabolism in cancer Catequentinib 💬 Anlotinib [1] 85 💬
179 FGFR3 💬 [12] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Regulation of actin cytoskeleton, Pathways in cancer, MicroRNAs in cancer, Bladder cancer, Central carbon metabolism in cancer Recifercept 💬 Recifercept [1] 276 💬
180 FLT3 💬 [8] MAPK signaling pathway, Ras signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Pathways in cancer, Transcriptional misregulation in cancer, Acute myeloid leukemia, Central carbon metabolism in cancer Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
181 FLT3 💬 [8] MAPK signaling pathway, Ras signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Pathways in cancer, Transcriptional misregulation in cancer, Acute myeloid leukemia, Central carbon metabolism in cancer Sorafenib 💬 Sorafenib [2] 34, 86 💬
182 FLT3 💬 [8] MAPK signaling pathway, Ras signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Pathways in cancer, Transcriptional misregulation in cancer, Acute myeloid leukemia, Central carbon metabolism in cancer Sunitinib malate 💬 Sunitinib [2] 28, 34 💬
183 FLT3 💬 [8] MAPK signaling pathway, Ras signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Pathways in cancer, Transcriptional misregulation in cancer, Acute myeloid leukemia, Central carbon metabolism in cancer Pacritinib 💬 Pacritinib [1] 331 💬
184 FLT3 💬 [8] MAPK signaling pathway, Ras signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Pathways in cancer, Transcriptional misregulation in cancer, Acute myeloid leukemia, Central carbon metabolism in cancer Sunitinib 💬 Sunitinib [2] 28, 34 💬
185 GAA 💬 [3] Galactose metabolism, Starch and sucrose metabolism, Lysosome Avalglucosidase alfa 💬 Avalglucosidase alfa [1] 256 💬
186 GAA 💬 [3] Galactose metabolism, Starch and sucrose metabolism, Lysosome Cipaglucosidase alfa 💬 Cipaglucosidase alfa [1] 256 💬
187 GAA 💬 [3] Galactose metabolism, Starch and sucrose metabolism, Lysosome Alglucosidase alfa 💬 Alglucosidase alfa [1] 256 💬
188 GAA 💬 [3] Galactose metabolism, Starch and sucrose metabolism, Lysosome Clervonafusp alfa 💬 Clervonafusp alfa [1] 309 💬
189 GAA 💬 [3] Galactose metabolism, Starch and sucrose metabolism, Lysosome Duvoglustat 💬 Duvoglustat [1] 256 💬
190 GAA 💬 [3] Galactose metabolism, Starch and sucrose metabolism, Lysosome Duvoglustat hydrochloride 💬 Duvoglustat [1] 256 💬
191 GAA 💬 [3] Galactose metabolism, Starch and sucrose metabolism, Lysosome Acarbose 💬 Acarbose [1] 298 💬
192 GAD1 💬 [6] Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, GABAergic synapse, Type I diabetes mellitus Valproate sodium 💬 Valproic acid [13] 2, 3, 5, 6, 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
193 GAD1 💬 [6] Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, GABAergic synapse, Type I diabetes mellitus Valproic acid 💬 Valproic acid [13] 2, 3, 5, 6, 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
194 GAD1 💬 [6] Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, GABAergic synapse, Type I diabetes mellitus Divalproex sodium 💬 Valproic acid [13] 2, 3, 5, 6, 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
195 GAD2 💬 [6] Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, GABAergic synapse, Type I diabetes mellitus Valproate sodium 💬 Valproic acid [13] 2, 3, 5, 6, 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
196 GAD2 💬 [6] Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, GABAergic synapse, Type I diabetes mellitus Valproic acid 💬 Valproic acid [13] 2, 3, 5, 6, 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
197 GAD2 💬 [6] Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism, Taurine and hypotaurine metabolism, Butanoate metabolism, GABAergic synapse, Type I diabetes mellitus Divalproex sodium 💬 Valproic acid [13] 2, 3, 5, 6, 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
198 GANC 💬 [2] Galactose metabolism, Starch and sucrose metabolism Acarbose 💬 Acarbose [1] 298 💬
199 GBA1 💬 [4] Other glycan degradation, Sphingolipid metabolism, Lysosome, Cornified envelope formation Velaglucerase alfa 💬 Velaglucerase alfa [1] 19 💬
200 GBA1 💬 [4] Other glycan degradation, Sphingolipid metabolism, Lysosome, Cornified envelope formation Alglucerase 💬 Imiglucerase [1] 19 💬
201 GBA1 💬 [4] Other glycan degradation, Sphingolipid metabolism, Lysosome, Cornified envelope formation Taliglucerase alfa 💬 Taliglucerase alfa [1] 19 💬
202 GBA1 💬 [4] Other glycan degradation, Sphingolipid metabolism, Lysosome, Cornified envelope formation Imiglucerase 💬 Imiglucerase [1] 19 💬
203 GLA 💬 [5] Galactose metabolism, Glycerolipid metabolism, Sphingolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome Agalsidase beta 💬 Agalsidase beta [1] 19 💬
204 GLA 💬 [5] Galactose metabolism, Glycerolipid metabolism, Sphingolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome Agalsidase alfa 💬 Agalsidase alfa [1] 19 💬
205 GLA 💬 [5] Galactose metabolism, Glycerolipid metabolism, Sphingolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome Migalastat hydrochloride 💬 Migalastat [1] 19 💬
206 GLA 💬 [5] Galactose metabolism, Glycerolipid metabolism, Sphingolipid metabolism, Glycosphingolipid biosynthesis - globo and isoglobo series, Lysosome Pegunigalsidase alfa 💬 Pegunigalsidase alfa [1] 19 💬
207 GUCY1A1 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Long-term depression, Oxytocin signaling pathway, Renin secretion, Salivary secretion Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
208 GUCY1A1 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Long-term depression, Oxytocin signaling pathway, Renin secretion, Salivary secretion Amyl nitrite 💬 Amyl Nitrite [1] 58 💬
209 GUCY1A1 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Long-term depression, Oxytocin signaling pathway, Renin secretion, Salivary secretion Avenciguat 💬 Avenciguat [1] 51 💬
210 GUCY1A1 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Long-term depression, Oxytocin signaling pathway, Renin secretion, Salivary secretion Vericiguat 💬 Vericiguat [1] 86 💬
211 GUCY1A1 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Long-term depression, Oxytocin signaling pathway, Renin secretion, Salivary secretion Zagociguat 💬 Zagociguat [1] 21 💬
212 GUCY1A2 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Long-term depression, Oxytocin signaling pathway, Renin secretion, Salivary secretion Zagociguat 💬 Zagociguat [1] 21 💬
213 GUCY1A2 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Long-term depression, Oxytocin signaling pathway, Renin secretion, Salivary secretion Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
214 GUCY1A2 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Long-term depression, Oxytocin signaling pathway, Renin secretion, Salivary secretion Vericiguat 💬 Vericiguat [1] 86 💬
215 GUCY1A2 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Long-term depression, Oxytocin signaling pathway, Renin secretion, Salivary secretion Amyl nitrite 💬 Amyl Nitrite [1] 58 💬
216 GUCY1A2 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Long-term depression, Oxytocin signaling pathway, Renin secretion, Salivary secretion Avenciguat 💬 Avenciguat [1] 51 💬
217 GUCY1B1 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Long-term depression, Oxytocin signaling pathway, Renin secretion, Salivary secretion Amyl nitrite 💬 Amyl Nitrite [1] 58 💬
218 GUCY1B1 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Long-term depression, Oxytocin signaling pathway, Renin secretion, Salivary secretion Vericiguat 💬 Vericiguat [1] 86 💬
219 GUCY1B1 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Long-term depression, Oxytocin signaling pathway, Renin secretion, Salivary secretion Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
220 GUCY1B1 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Long-term depression, Oxytocin signaling pathway, Renin secretion, Salivary secretion Avenciguat 💬 Avenciguat [1] 51 💬
221 GUCY1B1 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, Vascular smooth muscle contraction, Gap junction, Platelet activation, Circadian entrainment, Long-term depression, Oxytocin signaling pathway, Renin secretion, Salivary secretion Zagociguat 💬 Zagociguat [1] 21 💬
222 GUCY2C 💬 [2] Purine metabolism, Hormone signaling Linaclotide 💬 Linaclotide [2] 6, 97 💬
223 GUCY2C 💬 [2] Purine metabolism, Hormone signaling Linaclotide acetate 💬 Linaclotide [2] 6, 97 💬
224 GUSB 💬 [6] Pentose and glucuronate interconversions, Ascorbate and aldarate metabolism, Glycosaminoglycan degradation, Porphyrin metabolism, Drug metabolism - other enzymes, Lysosome Vestronidase alfa 💬 Vestronidase alfa [1] 19 💬
225 HAO1 💬 [2] Glyoxylate and dicarboxylate metabolism, Peroxisome Lumasiran sodium 💬 Lumasiran [1] 234 💬
226 HAO1 💬 [2] Glyoxylate and dicarboxylate metabolism, Peroxisome Lumasiran 💬 Lumasiran [1] 234 💬
227 HMGCR 💬
(Full name: 3-hydroxy-3-methylglutaryl-CoA reductase)		[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Lovastatin 💬 Lovastatin [11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
228 HMGCR 💬
(Full name: 3-hydroxy-3-methylglutaryl-CoA reductase)		[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Simvastatin 💬 Simvastatin [21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
229 HMGCR 💬
(Full name: 3-hydroxy-3-methylglutaryl-CoA reductase)		[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Pitavastatin magnesium 💬 Pitavastatin [1] 49 💬
230 HMGCR 💬
(Full name: 3-hydroxy-3-methylglutaryl-CoA reductase)		[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Atorvastatin 💬 Atorvastatin [20] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 225, 265, 271, 297, 299 💬
231 HMGCR 💬
(Full name: 3-hydroxy-3-methylglutaryl-CoA reductase)		[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Pravastatin 💬 Pravastatin [10] 13, 46, 49, 67, 79, 96, 164, 210, 265, 333 💬
232 HMGCR 💬
(Full name: 3-hydroxy-3-methylglutaryl-CoA reductase)		[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Rosuvastatin calcium 💬 Rosuvastatin [13] 6, 18, 46, 49, 51, 56, 65, 79, 94, 96, 97, 271, 299 💬
233 HMGCR 💬
(Full name: 3-hydroxy-3-methylglutaryl-CoA reductase)		[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Fluvastatin 💬 Fluvastatin [2] 79, 222 💬
234 HMGCR 💬
(Full name: 3-hydroxy-3-methylglutaryl-CoA reductase)		[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Pitavastatin calcium 💬 Pitavastatin [1] 49 💬
235 HMGCR 💬
(Full name: 3-hydroxy-3-methylglutaryl-CoA reductase)		[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Rosuvastatin 💬 Rosuvastatin [13] 6, 18, 46, 49, 51, 56, 65, 79, 94, 96, 97, 271, 299 💬
236 HMGCR 💬
(Full name: 3-hydroxy-3-methylglutaryl-CoA reductase)		[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Fluvastatin sodium 💬 Fluvastatin [2] 79, 222 💬
237 HMGCR 💬
(Full name: 3-hydroxy-3-methylglutaryl-CoA reductase)		[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Pravastatin sodium 💬 Pravastatin [10] 13, 46, 49, 67, 79, 96, 164, 210, 265, 333 💬
238 HMGCR 💬
(Full name: 3-hydroxy-3-methylglutaryl-CoA reductase)		[3] Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Atorvastatin calcium 💬 Atorvastatin [20] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 225, 265, 271, 297, 299 💬
239 HMOX1 💬 [9] Porphyrin metabolism, HIF-1 signaling pathway, Ferroptosis, Mineral absorption, Pathways in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis Stannsoporfin 💬 Stannsoporfin [1] 254 💬
240 HMOX2 💬 [2] Porphyrin metabolism, Mineral absorption Stannsoporfin 💬 Stannsoporfin [1] 254 💬
241 HPD 💬 [3] Ubiquinone and other terpenoid-quinone biosynthesis, Tyrosine metabolism, Phenylalanine metabolism Nitisinone 💬 Nitisinone [3] 6, 164, 241 💬
242 HPRT1 💬 [2] Purine metabolism, Drug metabolism - other enzymes Tioguanine 💬 Tioguanine [1] 13 💬
243 HPRT1 💬 [2] Purine metabolism, Drug metabolism - other enzymes Thioguanine 💬 Tioguanine [1] 13 💬
244 HPRT1 💬 [2] Purine metabolism, Drug metabolism - other enzymes Mercaptopurine 💬 Mercaptopurine [2] 96, 97 💬
245 HPRT1 💬 [2] Purine metabolism, Drug metabolism - other enzymes Mercaptopurine 💬 Mercaptopurine [2] 96, 97 💬
246 HSD11B1 💬 [3] Steroid hormone biosynthesis, Metabolism of xenobiotics by cytochrome P450, Chemical carcinogenesis - DNA adducts Dipotassium glycyrrhizinate 💬 Glycyrrhizic acid [2] 46, 51 💬
247 IMPDH1 💬 [2] Purine metabolism, Drug metabolism - other enzymes Mizoribine 💬 Mizoribine [8] 46, 49, 51, 53, 66, 94, 222, 224 💬
248 IMPDH1 💬 [2] Purine metabolism, Drug metabolism - other enzymes Mycophenolic acid 💬 Mycophenolic acid [37] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 84, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
249 IMPDH1 💬 [2] Purine metabolism, Drug metabolism - other enzymes Mycophenolate mofetil 💬 Mycophenolate mofetil [34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
250 IMPDH1 💬 [2] Purine metabolism, Drug metabolism - other enzymes Mycophenolate sodium 💬 Mycophenolic acid [37] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 84, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
251 IMPDH1 💬 [2] Purine metabolism, Drug metabolism - other enzymes Mycophenolate mofetil hydrochloride 💬 Mycophenolate mofetil [34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
252 IMPDH2 💬 [2] Purine metabolism, Drug metabolism - other enzymes Mycophenolic acid 💬 Mycophenolic acid [37] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 84, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
253 IMPDH2 💬 [2] Purine metabolism, Drug metabolism - other enzymes Mycophenolate mofetil 💬 Mycophenolate mofetil [34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
254 IMPDH2 💬 [2] Purine metabolism, Drug metabolism - other enzymes Mizoribine 💬 Mizoribine [8] 46, 49, 51, 53, 66, 94, 222, 224 💬
255 IMPDH2 💬 [2] Purine metabolism, Drug metabolism - other enzymes Mycophenolate mofetil hydrochloride 💬 Mycophenolate mofetil [34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
256 IMPDH2 💬 [2] Purine metabolism, Drug metabolism - other enzymes Mycophenolate sodium 💬 Mycophenolic acid [37] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 84, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
257 KIT 💬 [11] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer Dasatinib 💬 Dasatinib [2] 51, 85 💬
258 KIT 💬 [11] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer Pazopanib hydrochloride 💬 Pazopanib [1] 227 💬
259 KIT 💬 [11] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer Catequentinib 💬 Anlotinib [1] 85 💬
260 KIT 💬 [11] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
261 KIT 💬 [11] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer Nilotinib 💬 Nilotinib [5] 6, 8, 34, 51, 86 💬
262 KIT 💬 [11] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer Dasatinib 💬 Dasatinib [2] 51, 85 💬
263 KIT 💬 [11] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer Sorafenib 💬 Sorafenib [2] 34, 86 💬
264 KIT 💬 [11] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer Masitinib 💬 Masitinib [6] 2, 5, 6, 13, 46, 96 💬
265 KIT 💬 [11] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer Sunitinib 💬 Sunitinib [2] 28, 34 💬
266 KIT 💬 [11] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer Sunitinib malate 💬 Sunitinib [2] 28, 34 💬
267 KIT 💬 [11] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
268 KIT 💬 [11] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer Imatinib mesylate 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
269 KIT 💬 [11] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer, Acute myeloid leukemia, Breast cancer, Central carbon metabolism in cancer Barzolvolimab 💬 Barzolvolimab [1] 98 💬
270 LDHA 💬 [7] Glycolysis / Gluconeogenesis, Cysteine and methionine metabolism, Pyruvate metabolism, Propanoate metabolism, HIF-1 signaling pathway, Glucagon signaling pathway, Central carbon metabolism in cancer Nedosiran sodium 💬 Nedosiran [1] 234 💬
271 LIPA 💬 [4] Steroid biosynthesis, Lysosome, Efferocytosis, Cholesterol metabolism Sebelipase alfa 💬 Sebelipase alfa [1] 19 💬
272 LIPC 💬 [2] Glycerolipid metabolism, Cholesterol metabolism Dextran sulfate sodium 💬 Dextran [3] 2, 79, 97 💬
273 LPL 💬 [4] Glycerolipid metabolism, PPAR signaling pathway, Cholesterol metabolism, Alzheimer disease Dextran sulfate sodium 💬 Dextran [3] 2, 79, 97 💬
274 MAOA 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Moclobemide 💬 Moclobemide [1] 6 💬
275 MAOA 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Iproniazid phosphate 💬 Iproniazid [1] 6 💬
276 MAOA 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Phentermine 💬 Phentermine [1] 97 💬
277 MAOA 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Phentermine hydrochloride 💬 Phentermine [1] 97 💬
278 MAOA 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Iproniazid 💬 Iproniazid [1] 6 💬
279 MAOB 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Rasagiline mesylate 💬 Rasagiline [5] 2, 5, 6, 17, 66 💬
280 MAOB 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Rasagiline tartrate 💬 Rasagiline [5] 2, 5, 6, 17, 66 💬
281 MAOB 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Iproniazid phosphate 💬 Iproniazid [1] 6 💬
282 MAOB 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Phentermine 💬 Phentermine [1] 97 💬
283 MAOB 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Rasagiline 💬 Rasagiline [5] 2, 5, 6, 17, 66 💬
284 MAOB 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Safinamide mesylate 💬
(Safinamide methanesulfonate)		 Safinamide [2] 6, 17 💬
285 MAOB 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Iproniazid 💬 Iproniazid [1] 6 💬
286 MAOB 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Phentermine hydrochloride 💬 Phentermine [1] 97 💬
287 MAOB 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Safinamide 💬 Safinamide [2] 6, 17 💬
288 MAOB 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Selegiline 💬 Selegiline [1] 6 💬
289 MAOB 💬 [13] Glycine, serine and threonine metabolism, Arginine and proline metabolism, Histidine metabolism, Tyrosine metabolism, Phenylalanine metabolism, Tryptophan metabolism, Drug metabolism - cytochrome P450, Serotonergic synapse, Dopaminergic synapse, Parkinson disease, Cocaine addiction, Amphetamine addiction, Alcoholism Selegiline hydrochloride 💬 Selegiline [1] 6 💬
290 MAP2K1 💬 [88] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Oocyte meiosis, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, Osteoclast differentiation, Focal adhesion, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, TNF signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Cholinergic synapse, Serotonergic synapse, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Alcoholism, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Selumetinib sulfate 💬 Selumetinib [1] 34 💬
291 MAP2K1 💬 [88] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Oocyte meiosis, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, Osteoclast differentiation, Focal adhesion, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, TNF signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Cholinergic synapse, Serotonergic synapse, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Alcoholism, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Trametinib dimethyl sulfoxide 💬 Trametinib [6] 2, 34, 58, 195, 279, 280 💬
292 MAP2K1 💬 [88] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Oocyte meiosis, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, Osteoclast differentiation, Focal adhesion, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, TNF signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Cholinergic synapse, Serotonergic synapse, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Alcoholism, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Binimetinib 💬 Binimetinib [1] 34 💬
293 MAP2K1 💬 [88] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Oocyte meiosis, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, Osteoclast differentiation, Focal adhesion, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, TNF signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Cholinergic synapse, Serotonergic synapse, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Alcoholism, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Mirdametinib 💬 Mirdametinib [4] 34, 278, 279, 280 💬
294 MAP2K1 💬 [88] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Oocyte meiosis, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, Osteoclast differentiation, Focal adhesion, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, TNF signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Cholinergic synapse, Serotonergic synapse, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Alcoholism, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Cobimetinib 💬 Cobimetinib [1] 280 💬
295 MAP2K1 💬 [88] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Oocyte meiosis, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, Osteoclast differentiation, Focal adhesion, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, TNF signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Cholinergic synapse, Serotonergic synapse, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Alcoholism, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Cobimetinib fumarate 💬 Cobimetinib [1] 280 💬
296 MAP2K1 💬 [88] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Oocyte meiosis, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, Osteoclast differentiation, Focal adhesion, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, TNF signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Cholinergic synapse, Serotonergic synapse, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Alcoholism, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Selumetinib 💬 Selumetinib [1] 34 💬
297 MAP2K1 💬 [88] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Oocyte meiosis, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, Osteoclast differentiation, Focal adhesion, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, TNF signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Cholinergic synapse, Serotonergic synapse, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Alcoholism, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Trametinib 💬 Trametinib [6] 2, 34, 58, 195, 279, 280 💬
298 MAP2K2 💬 [76] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Cobimetinib fumarate 💬 Cobimetinib [1] 280 💬
299 MAP2K2 💬 [76] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Mirdametinib 💬 Mirdametinib [4] 34, 278, 279, 280 💬
300 MAP2K2 💬 [76] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Binimetinib 💬 Binimetinib [1] 34 💬
301 MAP2K2 💬 [76] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Cobimetinib 💬 Cobimetinib [1] 280 💬
302 MAP2K2 💬 [76] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Trametinib 💬 Trametinib [6] 2, 34, 58, 195, 279, 280 💬
303 MAP2K2 💬 [76] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Selumetinib 💬 Selumetinib [1] 34 💬
304 MAP2K2 💬 [76] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Trametinib dimethyl sulfoxide 💬 Trametinib [6] 2, 34, 58, 195, 279, 280 💬
305 MAP2K2 💬 [76] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Autophagy - animal, Efferocytosis, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, VEGF signaling pathway, Apelin signaling pathway, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, GnRH secretion, Cushing syndrome, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Salmonella infection, Yersinia infection, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Endometrial cancer, Glioma, Prostate cancer, Thyroid cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Selumetinib sulfate 💬 Selumetinib [1] 34 💬
306 MET 💬 [22] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Axon guidance, Focal adhesion, Adherens junction, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Malaria, Pathways in cancer, Transcriptional misregulation in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Renal cell carcinoma, Melanoma, Non-small cell lung cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer Cabozantinib 💬 Cabozantinib [1] 34 💬
307 MET 💬 [22] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Axon guidance, Focal adhesion, Adherens junction, Bacterial invasion of epithelial cells, Epithelial cell signaling in Helicobacter pylori infection, Malaria, Pathways in cancer, Transcriptional misregulation in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - reactive oxygen species, Renal cell carcinoma, Melanoma, Non-small cell lung cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer Cabozantinib s-malate 💬 Cabozantinib [1] 34 💬
308 MGAM 💬 [3] Galactose metabolism, Starch and sucrose metabolism, Carbohydrate digestion and absorption Acarbose 💬 Acarbose [1] 298 💬
309 MME 💬
(Full name: membrane metalloendopeptidase)		[4] Renin-angiotensin system, Hematopoietic cell lineage, Protein digestion and absorption, Alzheimer disease Sacubitril 💬 Sacubitril [3] 58, 210, 222 💬
310 MMP13 💬
(Full name: matrix metallopeptidase 13)		[3] IL-17 signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action Apratastat 💬 Apratastat [1] 46 💬
311 MMP9 💬
(Full name: matrix metallopeptidase 9)		[15] IL-17 signaling pathway, TNF signaling pathway, Leukocyte transendothelial migration, Estrogen signaling pathway, Relaxin signaling pathway, Hepatitis B, Pathways in cancer, Transcriptional misregulation in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Prostate cancer, Bladder cancer, Diabetic cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Andecaliximab 💬 Andecaliximab [5] 46, 96, 97, 272, 299 💬
312 MPO 💬 [5] Drug metabolism - other enzymes, Phagosome, Neutrophil extracellular trap formation, Transcriptional misregulation in cancer, Acute myeloid leukemia Verdiperstat 💬 Verdiperstat [2] 17, 127 💬
313 MTOR 💬 [49] ErbB signaling pathway, HIF-1 signaling pathway, Phospholipase D signaling pathway, Autophagy - other, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Cellular senescence, Apelin signaling pathway, Neutrophil extracellular trap formation, JAK-STAT signaling pathway, Th17 cell differentiation, Thermogenesis, Insulin signaling pathway, Thyroid hormone signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Growth hormone synthesis, secretion and action, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Shigellosis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Colorectal cancer, Pancreatic cancer, Glioma, Prostate cancer, Acute myeloid leukemia, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Diabetic cardiomyopathy Temsirolimus 💬 Temsirolimus [4] 13, 34, 89, 331 💬
314 MTOR 💬 [49] ErbB signaling pathway, HIF-1 signaling pathway, Phospholipase D signaling pathway, Autophagy - other, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Cellular senescence, Apelin signaling pathway, Neutrophil extracellular trap formation, JAK-STAT signaling pathway, Th17 cell differentiation, Thermogenesis, Insulin signaling pathway, Thyroid hormone signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Growth hormone synthesis, secretion and action, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Shigellosis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Colorectal cancer, Pancreatic cancer, Glioma, Prostate cancer, Acute myeloid leukemia, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Diabetic cardiomyopathy Everolimus 💬 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
315 MTOR 💬 [49] ErbB signaling pathway, HIF-1 signaling pathway, Phospholipase D signaling pathway, Autophagy - other, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Cellular senescence, Apelin signaling pathway, Neutrophil extracellular trap formation, JAK-STAT signaling pathway, Th17 cell differentiation, Thermogenesis, Insulin signaling pathway, Thyroid hormone signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Growth hormone synthesis, secretion and action, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Shigellosis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Colorectal cancer, Pancreatic cancer, Glioma, Prostate cancer, Acute myeloid leukemia, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Diabetic cardiomyopathy Sirolimus 💬 Sirolimus [46] 2, 6, 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
316 NOS1 💬 [17] Arginine biosynthesis, Arginine and proline metabolism, Calcium signaling pathway, Hormone signaling, Phagosome, Apelin signaling pathway, Circadian entrainment, Long-term depression, Relaxin signaling pathway, Salivary secretion, Alzheimer disease, Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Viral myocarditis Tilarginine acetate 💬 Tilarginine [1] 67 💬
317 NOS2 💬 [18] Arginine biosynthesis, Arginine and proline metabolism, Calcium signaling pathway, HIF-1 signaling pathway, Peroxisome, Apelin signaling pathway, Relaxin signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Pathways of neurodegeneration - multiple diseases, Pertussis, Leishmaniasis, Chagas disease, Toxoplasmosis, Amoebiasis, Tuberculosis, Pathways in cancer, Small cell lung cancer Tilarginine acetate 💬 Tilarginine [1] 67 💬
318 NOS3 💬 [18] Arginine biosynthesis, Arginine and proline metabolism, Calcium signaling pathway, cGMP-PKG signaling pathway, HIF-1 signaling pathway, Sphingolipid signaling pathway, PI3K-Akt signaling pathway, VEGF signaling pathway, Apelin signaling pathway, Platelet activation, Estrogen signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Insulin resistance, AGE-RAGE signaling pathway in diabetic complications, Diabetic cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Tilarginine acetate 💬 Tilarginine [1] 67 💬
319 NPR1 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Hormone signaling, Vascular smooth muscle contraction, Thermogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Aldosterone synthesis and secretion Nesiritide 💬 Nesiritide [1] 58 💬
320 NPR1 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Hormone signaling, Vascular smooth muscle contraction, Thermogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Aldosterone synthesis and secretion Erythrityl tetranitrate 💬 Erythrityl tetranitrate [1] 46 💬
321 NPR2 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, Hormone signaling, Vascular smooth muscle contraction, Oxytocin signaling pathway Vosoritide 💬 Vosoritide [3] 19, 195, 276 💬
322 NPR2 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, Hormone signaling, Vascular smooth muscle contraction, Oxytocin signaling pathway Erythrityl tetranitrate 💬 Erythrityl tetranitrate [1] 46 💬
323 PAH 💬 [3] Phenylalanine metabolism, Phenylalanine, tyrosine and tryptophan biosynthesis, Folate biosynthesis Pegvaliase 💬 Pegvaliase [1] 240 💬
324 PCSK9 💬 [1] Cholesterol metabolism Evolocumab 💬 Evolocumab [2] 79, 222 💬
325 PCSK9 💬 [1] Cholesterol metabolism Inclisiran 💬 Inclisiran [1] 79 💬
326 PCSK9 💬 [1] Cholesterol metabolism Alirocumab 💬 Alirocumab [1] 79 💬
327 PCSK9 💬 [1] Cholesterol metabolism Lerodalcibep 💬 Lerodalcibep [1] 79 💬
328 PCSK9 💬 [1] Cholesterol metabolism Inclisiran sodium 💬 Inclisiran [1] 79 💬
329 PDE10A 💬 [3] Purine metabolism, cAMP signaling pathway, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
330 PDE10A 💬 [3] Purine metabolism, cAMP signaling pathway, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
331 PDE10A 💬 [3] Purine metabolism, cAMP signaling pathway, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
332 PDE10A 💬 [3] Purine metabolism, cAMP signaling pathway, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
333 PDE10A 💬 [3] Purine metabolism, cAMP signaling pathway, Morphine addiction Aminophylline dihydrate 💬 Aminophylline [1] 63 💬
334 PDE10A 💬 [3] Purine metabolism, cAMP signaling pathway, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate [1] 226 💬
335 PDE10A 💬 [3] Purine metabolism, cAMP signaling pathway, Morphine addiction Theophylline sodium glycinate 💬 Theophylline [2] 236, 299 💬
336 PDE10A 💬 [3] Purine metabolism, cAMP signaling pathway, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
337 PDE11A 💬 [3] Purine metabolism, Cushing syndrome, Morphine addiction Aminophylline dihydrate 💬 Aminophylline [1] 63 💬
338 PDE11A 💬 [3] Purine metabolism, Cushing syndrome, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
339 PDE11A 💬 [3] Purine metabolism, Cushing syndrome, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
340 PDE11A 💬 [3] Purine metabolism, Cushing syndrome, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
341 PDE11A 💬 [3] Purine metabolism, Cushing syndrome, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate [1] 226 💬
342 PDE11A 💬 [3] Purine metabolism, Cushing syndrome, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
343 PDE11A 💬 [3] Purine metabolism, Cushing syndrome, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
344 PDE11A 💬 [3] Purine metabolism, Cushing syndrome, Morphine addiction Theophylline sodium glycinate 💬 Theophylline [2] 236, 299 💬
345 PDE1A 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate [1] 226 💬
346 PDE1A 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
347 PDE1A 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Theophylline sodium glycinate 💬 Theophylline [2] 236, 299 💬
348 PDE1A 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
349 PDE1A 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
350 PDE1A 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
351 PDE1A 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Aminophylline dihydrate 💬 Aminophylline [1] 63 💬
352 PDE1A 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
353 PDE1B 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Aminophylline dihydrate 💬 Aminophylline [1] 63 💬
354 PDE1B 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
355 PDE1B 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
356 PDE1B 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate [1] 226 💬
357 PDE1B 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
358 PDE1B 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
359 PDE1B 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Theophylline sodium glycinate 💬 Theophylline [2] 236, 299 💬
360 PDE1B 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
361 PDE1B 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Caffeine hydrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
362 PDE1B 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
363 PDE1B 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
364 PDE1C 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Theophylline sodium glycinate 💬 Theophylline [2] 236, 299 💬
365 PDE1C 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
366 PDE1C 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
367 PDE1C 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Aminophylline dihydrate 💬 Aminophylline [1] 63 💬
368 PDE1C 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
369 PDE1C 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate [1] 226 💬
370 PDE1C 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
371 PDE1C 💬 [6] Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
372 PDE2A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
373 PDE2A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
374 PDE2A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
375 PDE2A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate [1] 226 💬
376 PDE2A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
377 PDE2A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
378 PDE2A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
379 PDE2A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction Caffeine hydrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
380 PDE2A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
381 PDE2A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction Theophylline sodium glycinate 💬 Theophylline [2] 236, 299 💬
382 PDE2A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction Aminophylline dihydrate 💬 Aminophylline [1] 63 💬
383 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Ibudilast 💬 Ibudilast [2] 2, 13 💬
384 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
385 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Aminophylline dihydrate 💬 Aminophylline [1] 63 💬
386 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
387 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
388 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Cilostazol 💬 Cilostazol [5] 6, 46, 51, 70, 124 💬
389 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
390 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
391 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
392 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Caffeine hydrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
393 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Levosimendan 💬 Levosimendan [1] 2 💬
394 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Milrinone lactate 💬 Milrinone [1] 294 💬
395 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Theophylline sodium glycinate 💬 Theophylline [2] 236, 299 💬
396 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Milrinone 💬 Milrinone [1] 294 💬
397 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
398 PDE3A 💬 [5] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate [1] 226 💬
399 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Ibudilast 💬 Ibudilast [2] 2, 13 💬
400 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Milrinone 💬 Milrinone [1] 294 💬
401 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
402 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
403 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
404 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Levosimendan 💬 Levosimendan [1] 2 💬
405 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
406 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
407 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
408 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Milrinone lactate 💬 Milrinone [1] 294 💬
409 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
410 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Cilostazol 💬 Cilostazol [5] 6, 46, 51, 70, 124 💬
411 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Aminophylline dihydrate 💬 Aminophylline [1] 63 💬
412 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Theophylline sodium glycinate 💬 Theophylline [2] 236, 299 💬
413 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate [1] 226 💬
414 PDE3B 💬 [10] Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Caffeine hydrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
415 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
416 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Ibudilast 💬 Ibudilast [2] 2, 13 💬
417 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
418 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
419 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline sodium glycinate 💬 Theophylline [2] 236, 299 💬
420 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
421 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine hydrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
422 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
423 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Rolipram 💬 Rolipram [2] 8, 13 💬
424 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate [1] 226 💬
425 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
426 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Aminophylline dihydrate 💬 Aminophylline [1] 63 💬
427 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Dipyridamole 💬 Dipyridamole [5] 46, 51, 66, 96, 224 💬
428 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
429 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Apremilast 💬 Apremilast [8] 36, 46, 50, 56, 97, 107, 162, 271 💬
430 PDE4A 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬
431 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
432 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬
433 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
434 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
435 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
436 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
437 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Apremilast 💬 Apremilast [8] 36, 46, 50, 56, 97, 107, 162, 271 💬
438 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate [1] 226 💬
439 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Aminophylline dihydrate 💬 Aminophylline [1] 63 💬
440 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Ibudilast 💬 Ibudilast [2] 2, 13 💬
441 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline sodium glycinate 💬 Theophylline [2] 236, 299 💬
442 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
443 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine hydrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
444 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Rolipram 💬 Rolipram [2] 8, 13 💬
445 PDE4B 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
446 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
447 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline sodium glycinate 💬 Theophylline [2] 236, 299 💬
448 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
449 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate [1] 226 💬
450 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
451 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Aminophylline dihydrate 💬 Aminophylline [1] 63 💬
452 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬
453 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
454 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
455 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
456 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine hydrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
457 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Rolipram 💬 Rolipram [2] 8, 13 💬
458 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Apremilast 💬 Apremilast [8] 36, 46, 50, 56, 97, 107, 162, 271 💬
459 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
460 PDE4C 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Ibudilast 💬 Ibudilast [2] 2, 13 💬
461 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬
462 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Zatolmilast 💬 Zatolmilast [1] 206 💬
463 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
464 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
465 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Apremilast 💬 Apremilast [8] 36, 46, 50, 56, 97, 107, 162, 271 💬
466 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Aminophylline dihydrate 💬 Aminophylline [1] 63 💬
467 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
468 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
469 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
470 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Ibudilast 💬 Ibudilast [2] 2, 13 💬
471 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
472 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate [1] 226 💬
473 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Theophylline sodium glycinate 💬 Theophylline [2] 236, 299 💬
474 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
475 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Rolipram 💬 Rolipram [2] 8, 13 💬
476 PDE4D 💬 [4] Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Caffeine hydrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
477 PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway Dipyridamole 💬 Dipyridamole [5] 46, 51, 66, 96, 224 💬
478 PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway Udenafil 💬 Udenafil [2] 86, 210 💬
479 PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway Vardenafil 💬 Vardenafil [3] 13, 86, 299 💬
480 PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway Sildenafil 💬 Sildenafil [14] 6, 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
481 PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway Sildenafil citrate 💬 Sildenafil [14] 6, 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
482 PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway Caffeine citrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
483 PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway Tadalafil 💬 Tadalafil [8] 6, 51, 75, 77, 84, 86, 113, 210 💬
484 PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway Caffeine 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
485 PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway Caffeine hydrate 💬 Caffeine [8] 2, 6, 13, 21, 46, 96, 97, 265 💬
486 PDE5A 💬 [2] Purine metabolism, cGMP-PKG signaling pathway Vardenafil hydrochloride 💬 Vardenafil [3] 13, 86, 299 💬
487 PDE7A 💬 [2] Purine metabolism, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
488 PDE7A 💬 [2] Purine metabolism, Morphine addiction Theophylline sodium glycinate 💬 Theophylline [2] 236, 299 💬
489 PDE7A 💬 [2] Purine metabolism, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
490 PDE7A 💬 [2] Purine metabolism, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate [1] 226 💬
491 PDE7A 💬 [2] Purine metabolism, Morphine addiction Aminophylline dihydrate 💬 Aminophylline [1] 63 💬
492 PDE7A 💬 [2] Purine metabolism, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
493 PDE7A 💬 [2] Purine metabolism, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
494 PDE7A 💬 [2] Purine metabolism, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
495 PDE7B 💬 [2] Purine metabolism, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
496 PDE7B 💬 [2] Purine metabolism, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
497 PDE7B 💬 [2] Purine metabolism, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
498 PDE7B 💬 [2] Purine metabolism, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
499 PDE7B 💬 [2] Purine metabolism, Morphine addiction Aminophylline dihydrate 💬 Aminophylline [1] 63 💬
500 PDE7B 💬 [2] Purine metabolism, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
501 PDE7B 💬 [2] Purine metabolism, Morphine addiction Theophylline sodium glycinate 💬 Theophylline [2] 236, 299 💬
502 PDE7B 💬 [2] Purine metabolism, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate [1] 226 💬
503 PDE8A 💬 [4] Purine metabolism, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
504 PDE8A 💬 [4] Purine metabolism, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
505 PDE8A 💬 [4] Purine metabolism, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction Aminophylline dihydrate 💬 Aminophylline [1] 63 💬
506 PDE8A 💬 [4] Purine metabolism, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction Theophylline sodium glycinate 💬 Theophylline [2] 236, 299 💬
507 PDE8A 💬 [4] Purine metabolism, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate [1] 226 💬
508 PDE8A 💬 [4] Purine metabolism, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
509 PDE8A 💬 [4] Purine metabolism, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
510 PDE8A 💬 [4] Purine metabolism, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
511 PDE8B 💬 [4] Purine metabolism, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction Flavoxate hydrochloride 💬 Flavoxate [1] 226 💬
512 PDE8B 💬 [4] Purine metabolism, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction Theophylline sodium glycinate 💬 Theophylline [2] 236, 299 💬
513 PDE8B 💬 [4] Purine metabolism, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
514 PDE8B 💬 [4] Purine metabolism, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction Bucladesine 💬 Bucladesine [1] 246 💬
515 PDE8B 💬 [4] Purine metabolism, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction Aminophylline 💬 Aminophylline [1] 63 💬
516 PDE8B 💬 [4] Purine metabolism, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction Flavoxate 💬 Flavoxate [1] 226 💬
517 PDE8B 💬 [4] Purine metabolism, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction Theophylline 💬 Theophylline [2] 236, 299 💬
518 PDE8B 💬 [4] Purine metabolism, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction Aminophylline dihydrate 💬 Aminophylline [1] 63 💬
519 PDGFRA 💬 [19] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human cytomegalovirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Sunitinib malate 💬 Sunitinib [2] 28, 34 💬
520 PDGFRA 💬 [19] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human cytomegalovirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Pazopanib hydrochloride 💬 Pazopanib [1] 227 💬
521 PDGFRA 💬 [19] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human cytomegalovirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Catequentinib 💬 Anlotinib [1] 85 💬
522 PDGFRA 💬 [19] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human cytomegalovirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Sunitinib 💬 Sunitinib [2] 28, 34 💬
523 PDGFRA 💬 [19] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human cytomegalovirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Nintedanib esylate 💬 Nintedanib [7] 51, 84, 85, 89, 227, 228, 331 💬
524 PDGFRA 💬 [19] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human cytomegalovirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Imatinib 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
525 PDGFRA 💬 [19] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human cytomegalovirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Nintedanib 💬 Nintedanib [7] 51, 84, 85, 89, 227, 228, 331 💬
526 PDGFRA 💬 [19] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human cytomegalovirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Seralutinib 💬 Seralutinib [1] 86 💬
527 PDGFRA 💬 [19] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human cytomegalovirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Nilotinib 💬 Nilotinib [5] 6, 8, 34, 51, 86 💬
528 PDGFRA 💬 [19] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, Endocytosis, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human cytomegalovirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Imatinib mesylate 💬 Imatinib [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
529 PDGFRB 💬 [18] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human papillomavirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Dasatinib 💬 Dasatinib [2] 51, 85 💬
530 PDGFRB 💬 [18] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human papillomavirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Seralutinib 💬 Seralutinib [1] 86 💬
531 PDGFRB 💬 [18] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human papillomavirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Sunitinib malate 💬 Sunitinib [2] 28, 34 💬
532 PDGFRB 💬 [18] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human papillomavirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Nintedanib esylate 💬 Nintedanib [7] 51, 84, 85, 89, 227, 228, 331 💬
533 PDGFRB 💬 [18] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human papillomavirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Catequentinib 💬 Anlotinib [1] 85 💬
534 PDGFRB 💬 [18] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human papillomavirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Sorafenib 💬 Sorafenib [2] 34, 86 💬
535 PDGFRB 💬 [18] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human papillomavirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Nintedanib 💬 Nintedanib [7] 51, 84, 85, 89, 227, 228, 331 💬
536 PDGFRB 💬 [18] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human papillomavirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
537 PDGFRB 💬 [18] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human papillomavirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Nilotinib 💬 Nilotinib [5] 6, 8, 34, 51, 86 💬
538 PDGFRB 💬 [18] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human papillomavirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Pazopanib hydrochloride 💬 Pazopanib [1] 227 💬
539 PDGFRB 💬 [18] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human papillomavirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Dasatinib 💬 Dasatinib [2] 51, 85 💬
540 PDGFRB 💬 [18] MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Phospholipase D signaling pathway, PI3K-Akt signaling pathway, Focal adhesion, Gap junction, JAK-STAT signaling pathway, Regulation of actin cytoskeleton, Human papillomavirus infection, Pathways in cancer, MicroRNAs in cancer, Glioma, Prostate cancer, Melanoma, Central carbon metabolism in cancer, Choline metabolism in cancer Sunitinib 💬 Sunitinib [2] 28, 34 💬
541 PIK3C3 💬 [15] Inositol phosphate metabolism, Phosphatidylinositol signaling system, Autophagy - other, Autophagy - animal, Phagosome, Apelin signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Shigellosis, Salmonella infection, Tuberculosis, Kaposi sarcoma-associated herpesvirus infection Fimepinostat 💬 Fimepinostat [1] 75 💬
542 PIK3CA 💬 [103] Inositol phosphate metabolism, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Hormone signaling, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Apoptosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Cellular senescence, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, Focal adhesion, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, TNF signaling pathway, Leukocyte transendothelial migration, Neurotrophin signaling pathway, Cholinergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, GnRH secretion, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Aldosterone-regulated sodium reabsorption, Carbohydrate digestion and absorption, Alzheimer disease, Spinocerebellar ataxia, Prion disease, Bacterial invasion of epithelial cells, Shigellosis, Salmonella infection, Yersinia infection, Chagas disease, Amoebiasis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease - COVID-19, Pathways in cancer, Viral carcinogenesis, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Chronic myeloid leukemia, Acute myeloid leukemia, Small cell lung cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Diabetic cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Copanlisib 💬 Copanlisib [1] 121 💬
543 PIK3CA 💬 [103] Inositol phosphate metabolism, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Hormone signaling, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Apoptosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Cellular senescence, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, Focal adhesion, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, TNF signaling pathway, Leukocyte transendothelial migration, Neurotrophin signaling pathway, Cholinergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, GnRH secretion, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Aldosterone-regulated sodium reabsorption, Carbohydrate digestion and absorption, Alzheimer disease, Spinocerebellar ataxia, Prion disease, Bacterial invasion of epithelial cells, Shigellosis, Salmonella infection, Yersinia infection, Chagas disease, Amoebiasis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease - COVID-19, Pathways in cancer, Viral carcinogenesis, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Chronic myeloid leukemia, Acute myeloid leukemia, Small cell lung cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Diabetic cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Alpelisib 💬 Alpelisib [4] 138, 278, 279, 280 💬
544 PIK3CA 💬 [103] Inositol phosphate metabolism, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Hormone signaling, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Apoptosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Cellular senescence, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, Focal adhesion, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, TNF signaling pathway, Leukocyte transendothelial migration, Neurotrophin signaling pathway, Cholinergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, GnRH secretion, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Aldosterone-regulated sodium reabsorption, Carbohydrate digestion and absorption, Alzheimer disease, Spinocerebellar ataxia, Prion disease, Bacterial invasion of epithelial cells, Shigellosis, Salmonella infection, Yersinia infection, Chagas disease, Amoebiasis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease - COVID-19, Pathways in cancer, Viral carcinogenesis, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Chronic myeloid leukemia, Acute myeloid leukemia, Small cell lung cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Diabetic cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Leniolisib 💬 Leniolisib [2] 53, 65 💬
545 PIK3CB 💬 [103] Inositol phosphate metabolism, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Hormone signaling, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Apoptosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Cellular senescence, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, Focal adhesion, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, TNF signaling pathway, Leukocyte transendothelial migration, Neurotrophin signaling pathway, Cholinergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, GnRH secretion, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Aldosterone-regulated sodium reabsorption, Carbohydrate digestion and absorption, Alzheimer disease, Spinocerebellar ataxia, Prion disease, Bacterial invasion of epithelial cells, Shigellosis, Salmonella infection, Yersinia infection, Chagas disease, Amoebiasis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease - COVID-19, Pathways in cancer, Viral carcinogenesis, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Chronic myeloid leukemia, Acute myeloid leukemia, Small cell lung cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Diabetic cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Leniolisib 💬 Leniolisib [2] 53, 65 💬
546 PIK3CD 💬 [103] Inositol phosphate metabolism, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Hormone signaling, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Apoptosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Cellular senescence, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, Focal adhesion, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, TNF signaling pathway, Leukocyte transendothelial migration, Neurotrophin signaling pathway, Cholinergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, GnRH secretion, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Aldosterone-regulated sodium reabsorption, Carbohydrate digestion and absorption, Alzheimer disease, Spinocerebellar ataxia, Prion disease, Bacterial invasion of epithelial cells, Shigellosis, Salmonella infection, Yersinia infection, Chagas disease, Amoebiasis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease - COVID-19, Pathways in cancer, Viral carcinogenesis, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Chronic myeloid leukemia, Acute myeloid leukemia, Small cell lung cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Diabetic cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Leniolisib phosphate 💬 Leniolisib [2] 53, 65 💬
547 PIK3CD 💬 [103] Inositol phosphate metabolism, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Hormone signaling, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Apoptosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Cellular senescence, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, Focal adhesion, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, TNF signaling pathway, Leukocyte transendothelial migration, Neurotrophin signaling pathway, Cholinergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, GnRH secretion, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Aldosterone-regulated sodium reabsorption, Carbohydrate digestion and absorption, Alzheimer disease, Spinocerebellar ataxia, Prion disease, Bacterial invasion of epithelial cells, Shigellosis, Salmonella infection, Yersinia infection, Chagas disease, Amoebiasis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease - COVID-19, Pathways in cancer, Viral carcinogenesis, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Chronic myeloid leukemia, Acute myeloid leukemia, Small cell lung cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Diabetic cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Copanlisib 💬 Copanlisib [1] 121 💬
548 PIK3CD 💬 [103] Inositol phosphate metabolism, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Hormone signaling, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Apoptosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Cellular senescence, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, Focal adhesion, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, TNF signaling pathway, Leukocyte transendothelial migration, Neurotrophin signaling pathway, Cholinergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, GnRH secretion, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Aldosterone-regulated sodium reabsorption, Carbohydrate digestion and absorption, Alzheimer disease, Spinocerebellar ataxia, Prion disease, Bacterial invasion of epithelial cells, Shigellosis, Salmonella infection, Yersinia infection, Chagas disease, Amoebiasis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease - COVID-19, Pathways in cancer, Viral carcinogenesis, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Chronic myeloid leukemia, Acute myeloid leukemia, Small cell lung cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Diabetic cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Leniolisib 💬 Leniolisib [2] 53, 65 💬
549 PIK3CD 💬 [103] Inositol phosphate metabolism, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, HIF-1 signaling pathway, FoxO signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Hormone signaling, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, Apoptosis, Longevity regulating pathway, Longevity regulating pathway - multiple species, Cellular senescence, Axon guidance, VEGF signaling pathway, Osteoclast differentiation, Focal adhesion, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, TNF signaling pathway, Leukocyte transendothelial migration, Neurotrophin signaling pathway, Cholinergic synapse, Inflammatory mediator regulation of TRP channels, Regulation of actin cytoskeleton, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Prolactin signaling pathway, Thyroid hormone signaling pathway, Regulation of lipolysis in adipocytes, Relaxin signaling pathway, GnRH secretion, Type II diabetes mellitus, Insulin resistance, Non-alcoholic fatty liver disease, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Aldosterone-regulated sodium reabsorption, Carbohydrate digestion and absorption, Alzheimer disease, Spinocerebellar ataxia, Prion disease, Bacterial invasion of epithelial cells, Shigellosis, Salmonella infection, Yersinia infection, Chagas disease, Amoebiasis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Herpes simplex virus 1 infection, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection, Coronavirus disease - COVID-19, Pathways in cancer, Viral carcinogenesis, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Chronic myeloid leukemia, Acute myeloid leukemia, Small cell lung cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, Diabetic cardiomyopathy, Lipid and atherosclerosis, Fluid shear stress and atherosclerosis Parsaclisib 💬 Parsaclisib [3] 35, 53, 61 💬
550 PRKCB 💬 [71] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Chemokine signaling pathway, NF-kappa B signaling pathway, HIF-1 signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Neuroactive ligand signaling, mTOR signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, VEGF signaling pathway, Focal adhesion, Gap junction, Neutrophil extracellular trap formation, Natural killer cell mediated cytotoxicity, B cell receptor signaling pathway, Fc gamma R-mediated phagocytosis, Leukocyte transendothelial migration, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Long-term depression, Inflammatory mediator regulation of TRP channels, Insulin secretion, GnRH signaling pathway, Melanogenesis, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Aldosterone synthesis and secretion, Parathyroid hormone synthesis, secretion and action, GnRH secretion, Insulin resistance, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Morphine addiction, Leishmaniasis, African trypanosomiasis, Amoebiasis, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human immunodeficiency virus 1 infection, Coronavirus disease - COVID-19, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Glioma, Non-small cell lung cancer, Hepatocellular carcinoma, Choline metabolism in cancer, Diabetic cardiomyopathy Enzastaurin 💬 Enzastaurin [1] 168 💬
551 PRKCB 💬 [71] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, Calcium signaling pathway, Chemokine signaling pathway, NF-kappa B signaling pathway, HIF-1 signaling pathway, Phosphatidylinositol signaling system, Sphingolipid signaling pathway, Neuroactive ligand signaling, mTOR signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, VEGF signaling pathway, Focal adhesion, Gap junction, Neutrophil extracellular trap formation, Natural killer cell mediated cytotoxicity, B cell receptor signaling pathway, Fc gamma R-mediated phagocytosis, Leukocyte transendothelial migration, Circadian entrainment, Long-term potentiation, Retrograde endocannabinoid signaling, Glutamatergic synapse, Cholinergic synapse, Serotonergic synapse, GABAergic synapse, Dopaminergic synapse, Long-term depression, Inflammatory mediator regulation of TRP channels, Insulin secretion, GnRH signaling pathway, Melanogenesis, Thyroid hormone synthesis, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Aldosterone synthesis and secretion, Parathyroid hormone synthesis, secretion and action, GnRH secretion, Insulin resistance, AGE-RAGE signaling pathway in diabetic complications, Growth hormone synthesis, secretion and action, Aldosterone-regulated sodium reabsorption, Endocrine and other factor-regulated calcium reabsorption, Salivary secretion, Gastric acid secretion, Pancreatic secretion, Carbohydrate digestion and absorption, Spinocerebellar ataxia, Pathways of neurodegeneration - multiple diseases, Amphetamine addiction, Morphine addiction, Leishmaniasis, African trypanosomiasis, Amoebiasis, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human immunodeficiency virus 1 infection, Coronavirus disease - COVID-19, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Glioma, Non-small cell lung cancer, Hepatocellular carcinoma, Choline metabolism in cancer, Diabetic cardiomyopathy Enzastaurin hydrochloride 💬 Enzastaurin [1] 168 💬
552 PTGES 💬 [1] Arachidonic acid metabolism Aceclofenac 💬 Aceclofenac [1] 46 💬
553 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Diclofenac potassium 💬 Diclofenac [4] 13, 34, 46, 271 💬
554 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Naproxen sodium 💬 Naproxen [4] 13, 46, 107, 271 💬
555 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Tolfenamic acid 💬 Tolfenamic acid [1] 5 💬
556 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Indomethacin 💬 Indomethacin [3] 225, 271, 298 💬
557 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Salsalate 💬 Salsalate [1] 5 💬
558 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Ketoprofen sodium 💬 Ketoprofen [2] 13, 46 💬
559 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Ketorolac tromethamine 💬 Ketorolac [2] 70, 226 💬
560 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Ketoprofen 💬 Ketoprofen [2] 13, 46 💬
561 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Flurbiprofen sodium 💬 Flurbiprofen [3] 13, 21, 46 💬
562 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Ibuprofen sodium 💬 Ibuprofen [6] 13, 46, 65, 113, 271, 299 💬
563 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Acetaminophen 💬 Acetaminophen [18] 3, 6, 11, 13, 19, 34, 35, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
564 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Sulindac 💬 Sulindac [1] 206 💬
565 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Loxoprofen 💬 Loxoprofen [2] 46, 271 💬
566 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Naproxen 💬 Naproxen [4] 13, 46, 107, 271 💬
567 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Ibuprofen 💬 Ibuprofen [6] 13, 46, 65, 113, 271, 299 💬
568 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Ibuprofen sodium 💬 Ibuprofen [6] 13, 46, 65, 113, 271, 299 💬
569 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Aceclofenac 💬 Aceclofenac [1] 46 💬
570 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Indomethacin sodium 💬 Indomethacin [3] 225, 271, 298 💬
571 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Diclofenac epolamine 💬 Diclofenac [4] 13, 34, 46, 271 💬
572 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Diclofenac sodium 💬 Diclofenac [4] 13, 34, 46, 271 💬
573 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Diclofenac 💬 Diclofenac [4] 13, 34, 46, 271 💬
574 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Ketorolac 💬 Ketorolac [2] 70, 226 💬
575 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Diclofenac diethylamine 💬 Diclofenac [4] 13, 34, 46, 271 💬
576 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Flurbiprofen 💬 Flurbiprofen [3] 13, 21, 46 💬
577 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Ibuprofen lysine 💬 Ibuprofen [6] 13, 46, 65, 113, 271, 299 💬
578 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Ibuprofen aluminum 💬 Ibuprofen [6] 13, 46, 65, 113, 271, 299 💬
579 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Aspirin 💬 Acetylsalicylic acid [15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬
580 PTGS1 💬 [4] Arachidonic acid metabolism, Platelet activation, Serotonergic synapse, Regulation of lipolysis in adipocytes Ketoprofen lysine 💬 Ketoprofen [2] 13, 46 💬
581 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Diclofenac epolamine 💬 Diclofenac [4] 13, 34, 46, 271 💬
582 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Acetaminophen 💬 Acetaminophen [18] 3, 6, 11, 13, 19, 34, 35, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
583 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Ibuprofen sodium 💬 Ibuprofen [6] 13, 46, 65, 113, 271, 299 💬
584 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Ketorolac 💬 Ketorolac [2] 70, 226 💬
585 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Diflunisal 💬 Diflunisal [1] 28 💬
586 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Ibuprofen sodium 💬 Ibuprofen [6] 13, 46, 65, 113, 271, 299 💬
587 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Naproxen sodium 💬 Naproxen [4] 13, 46, 107, 271 💬
588 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Diclofenac diethylamine 💬 Diclofenac [4] 13, 34, 46, 271 💬
589 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Valdecoxib 💬 Parecoxib [2] 46, 271 💬
590 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Loxoprofen 💬 Loxoprofen [2] 46, 271 💬
591 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Rofecoxib 💬 Rofecoxib [1] 46 💬
592 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Diclofenac sodium 💬 Diclofenac [4] 13, 34, 46, 271 💬
593 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Aspirin 💬 Acetylsalicylic acid [15] 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬
594 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Parecoxib 💬 Parecoxib [2] 46, 271 💬
595 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Ketorolac tromethamine 💬 Ketorolac [2] 70, 226 💬
596 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Ibuprofen lysine 💬 Ibuprofen [6] 13, 46, 65, 113, 271, 299 💬
597 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Parecoxib sodium 💬 Parecoxib [2] 46, 271 💬
598 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Etoricoxib 💬 Etoricoxib [3] 46, 70, 271 💬
599 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Tolfenamic acid 💬 Tolfenamic acid [1] 5 💬
600 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Lumiracoxib 💬 Lumiracoxib [1] 46 💬
601 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Meloxicam 💬 Meloxicam [3] 46, 271, 296 💬
602 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Ibuprofen aluminum 💬 Ibuprofen [6] 13, 46, 65, 113, 271, 299 💬
603 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Flurbiprofen sodium 💬 Flurbiprofen [3] 13, 21, 46 💬
604 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Indomethacin sodium 💬 Indomethacin [3] 225, 271, 298 💬
605 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Diclofenac potassium 💬 Diclofenac [4] 13, 34, 46, 271 💬
606 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Indomethacin 💬 Indomethacin [3] 225, 271, 298 💬
607 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Flurbiprofen 💬 Flurbiprofen [3] 13, 21, 46 💬
608 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Nimesulide 💬 Nimesulide [1] 46 💬
609 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Ketoprofen sodium 💬 Ketoprofen [2] 13, 46 💬
610 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Diclofenac 💬 Diclofenac [4] 13, 34, 46, 271 💬
611 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Ketoprofen lysine 💬 Ketoprofen [2] 13, 46 💬
612 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Salsalate 💬 Salsalate [1] 5 💬
613 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Ketoprofen 💬 Ketoprofen [2] 13, 46 💬
614 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Sulindac 💬 Sulindac [1] 206 💬
615 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Aceclofenac 💬 Aceclofenac [1] 46 💬
616 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Celecoxib 💬 Celecoxib [14] 2, 3, 6, 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬
617 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Ibuprofen 💬 Ibuprofen [6] 13, 46, 65, 113, 271, 299 💬
618 PTGS2 💬 [22] Arachidonic acid metabolism, NF-kappa B signaling pathway, Efferocytosis, VEGF signaling pathway, C-type lectin receptor signaling pathway, IL-17 signaling pathway, TNF signaling pathway, Retrograde endocannabinoid signaling, Serotonergic synapse, Ovarian steroidogenesis, Oxytocin signaling pathway, Regulation of lipolysis in adipocytes, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Leishmaniasis, Human cytomegalovirus infection, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Pathways in cancer, Chemical carcinogenesis - DNA adducts, MicroRNAs in cancer, Small cell lung cancer Naproxen 💬 Naproxen [4] 13, 46, 107, 271 💬
619 RAF1 💬 [81] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, Axon guidance, VEGF signaling pathway, Apelin signaling pathway, Focal adhesion, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Long-term potentiation, Neurotrophin signaling pathway, Serotonergic synapse, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, GnRH secretion, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Alcoholism, Salmonella infection, Tuberculosis, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
620 RAF1 💬 [81] MAPK signaling pathway, ErbB signaling pathway, Ras signaling pathway, Rap1 signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Chemokine signaling pathway, FoxO signaling pathway, Sphingolipid signaling pathway, Phospholipase D signaling pathway, Autophagy - animal, mTOR signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Cellular senescence, Vascular smooth muscle contraction, Axon guidance, VEGF signaling pathway, Apelin signaling pathway, Focal adhesion, Gap junction, Signaling pathways regulating pluripotency of stem cells, Neutrophil extracellular trap formation, C-type lectin receptor signaling pathway, JAK-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Long-term potentiation, Neurotrophin signaling pathway, Serotonergic synapse, Long-term depression, Regulation of actin cytoskeleton, Insulin signaling pathway, GnRH signaling pathway, Progesterone-mediated oocyte maturation, Estrogen signaling pathway, Melanogenesis, Prolactin signaling pathway, Thyroid hormone signaling pathway, Oxytocin signaling pathway, Relaxin signaling pathway, Parathyroid hormone synthesis, secretion and action, GnRH secretion, Growth hormone synthesis, secretion and action, Alzheimer disease, Pathways of neurodegeneration - multiple diseases, Alcoholism, Salmonella infection, Tuberculosis, Hepatitis C, Hepatitis B, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Human immunodeficiency virus 1 infection, Pathways in cancer, Proteoglycans in cancer, MicroRNAs in cancer, Chemical carcinogenesis - receptor activation, Chemical carcinogenesis - reactive oxygen species, Colorectal cancer, Renal cell carcinoma, Pancreatic cancer, Endometrial cancer, Glioma, Prostate cancer, Melanoma, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer, Central carbon metabolism in cancer, Choline metabolism in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer Sorafenib 💬 Sorafenib [2] 34, 86 💬
621 RET 💬 [7] MAPK signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Thyroid cancer, Non-small cell lung cancer, Central carbon metabolism in cancer Sorafenib tosylate 💬 Sorafenib [2] 34, 86 💬
622 RET 💬 [7] MAPK signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Thyroid cancer, Non-small cell lung cancer, Central carbon metabolism in cancer Sunitinib 💬 Sunitinib [2] 28, 34 💬
623 RET 💬 [7] MAPK signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Thyroid cancer, Non-small cell lung cancer, Central carbon metabolism in cancer Sorafenib 💬 Sorafenib [2] 34, 86 💬
624 RET 💬 [7] MAPK signaling pathway, Calcium signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Thyroid cancer, Non-small cell lung cancer, Central carbon metabolism in cancer Sunitinib malate 💬 Sunitinib [2] 28, 34 💬
625 RRM1 💬 [4] Purine metabolism, Pyrimidine metabolism, Glutathione metabolism, Drug metabolism - other enzymes Clofarabine 💬 Clofarabine [5] 19, 20, 60, 96, 234 💬
626 RRM1 💬 [4] Purine metabolism, Pyrimidine metabolism, Glutathione metabolism, Drug metabolism - other enzymes Fludarabine 💬 Fludarabine [25] 11, 13, 19, 28, 34, 35, 36, 44, 46, 49, 51, 60, 61, 62, 65, 85, 96, 107, 164, 222, 283, 284, 285, 286, 326 💬
627 RRM1 💬 [4] Purine metabolism, Pyrimidine metabolism, Glutathione metabolism, Drug metabolism - other enzymes Fludarabine phosphate 💬 Fludarabine [25] 11, 13, 19, 28, 34, 35, 36, 44, 46, 49, 51, 60, 61, 62, 65, 85, 96, 107, 164, 222, 283, 284, 285, 286, 326 💬
628 RRM1 💬 [4] Purine metabolism, Pyrimidine metabolism, Glutathione metabolism, Drug metabolism - other enzymes Cladribine 💬 Cladribine [3] 11, 13, 94 💬
629 RRM2 💬 [5] Purine metabolism, Pyrimidine metabolism, Glutathione metabolism, Drug metabolism - other enzymes, p53 signaling pathway Hydroxyurea 💬 Hydroxyurea [10] 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
630 SMPD1 💬 [4] Sphingolipid metabolism, Sphingolipid signaling pathway, Lysosome, Necroptosis Olipudase alfa 💬 Olipudase alfa [1] 19 💬
631 SORT1 💬 [3] Lysosome, Neurotrophin signaling pathway, Cholesterol metabolism Latozinemab 💬 Latozinemab [2] 2, 127 💬
632 TPH1 💬 [3] Tryptophan metabolism, Folate biosynthesis, Serotonergic synapse Rodatristat 💬 Rodatristat [1] 86 💬
633 TPH1 💬 [3] Tryptophan metabolism, Folate biosynthesis, Serotonergic synapse Rodatristat ethyl 💬 Rodatristat ethyl [1] 86 💬
634 TPH1 💬 [3] Tryptophan metabolism, Folate biosynthesis, Serotonergic synapse Telotristat 💬 Telotristat [1] 97 💬
635 TPH2 💬 [3] Tryptophan metabolism, Folate biosynthesis, Serotonergic synapse Telotristat 💬 Telotristat [1] 97 💬
636 TPO 💬 [3] Tyrosine metabolism, Thyroid hormone synthesis, Autoimmune thyroid disease Methimazole 💬
(Methimazole)		 Methimazole [1] 50 💬
637 TYMS 💬 [3] Pyrimidine metabolism, One carbon pool by folate, Folate transport and metabolism Capecitabine 💬 Capecitabine [1] 94 💬
638 UGCG 💬 [2] Sphingolipid metabolism, Cornified envelope formation Eliglustat tartrate 💬 Eliglustat [1] 19 💬
639 UGCG 💬 [2] Sphingolipid metabolism, Cornified envelope formation Miglustat 💬 Miglustat [3] 19, 256, 299 💬
640 UGCG 💬 [2] Sphingolipid metabolism, Cornified envelope formation Lucerastat 💬 Lucerastat [1] 19 💬
641 UGCG 💬 [2] Sphingolipid metabolism, Cornified envelope formation Eliglustat 💬 Eliglustat [1] 19 💬
642 UGCG 💬 [2] Sphingolipid metabolism, Cornified envelope formation Venglustat 💬 Venglustat [3] 6, 19, 67 💬
643 XDH 💬 [4] Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome Febuxostat hydrate 💬 Febuxostat [4] 2, 6, 13, 97 💬
644 XDH 💬 [4] Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome Allopurinol sodium 💬 Allopurinol [7] 6, 46, 57, 60, 66, 96, 97 💬
645 XDH 💬 [4] Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome Febuxostat 💬 Febuxostat [4] 2, 6, 13, 97 💬
646 XDH 💬 [4] Purine metabolism, Caffeine metabolism, Drug metabolism - other enzymes, Peroxisome Allopurinol 💬 Allopurinol [7] 6, 46, 57, 60, 66, 96, 97 💬