Drug Description in Trials / DrugBank / KEGG DRUG /

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(4S)-4-[4-cyano-2-(methylsulfonyl)phenyl]-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carbonitrile----[1] 231
24-PBA----[1] 231
3Abdominal ultrasound----[1] 231
4Acetaminophen[1] Acetaminophen[1] D00217 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[16] 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
5ADS-001----[1] 231
6Aerosolized human Alpha-1 Antitrypsin----[1] 231
7Albumin (Human) 20%, United States Pharmacopeia (USP)----[1] 231
8Albuterol[1] Salbutamol[1] D02147 [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 12, 13, 86, 89, 113, 231, 256, 299
9Albuterol inhaler.[1] Salbutamol[1] D02147 [1] ADRB2 💬[9] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 231, 299
10ALN-61444----[1] 231
11ALN-77412----[1] 231
12ALN-AAT----[1] 231
13ALN-AAT02----[1] 231
14Alpha 1-Antitrypsin[1] Alpha-1-proteinase inhibitor---[2] 231, 298
15Alpha 1-Proteinase Inhibitor[1] Alpha-1-proteinase inhibitor---[1] 231
16Alpha 1-proteinase inhibitor (human)[1] Alpha-1-proteinase inhibitor---[1] 231
17Alpha-1 Antitrypsin (AAT)----[1] 231
18Alpha-1 Antitrypsin (human)----[1] 231
19Alpha-1 MP----[1] 231
20Alpha-1 proteinase inhibitor (human)----[1] 231
21ALPHA-1-ANTITRYPSIN[1] Alpha-1-proteinase inhibitor---[1] 231
22Alpha1-Proteinase Inhibitor[1] Alpha-1-proteinase inhibitor---[2] 231, 299
23Alpha1-Proteinase Inhibitor (Human)[1] Alpha-1-proteinase inhibitor---[2] 231, 299
24ALVELESTAT[1] Alvelestat---[1] 231
25Alvelestat (MPH966)[1] Alvelestat---[1] 231
26Alvelestat oral tablet - dose 1[1] Alvelestat---[1] 231
27Alvelestat oral tablet - dose 2[1] Alvelestat---[1] 231
28Alvelestat tosylate[1] Alvelestat---[1] 231
29API----[2] 231, 299
30API-AAT----[1] 231
31API-AAT, AD00370, ARC-AAT, API drug Substance----[1] 231
32ARC-AAT----[1] 231
33ARC-AAT Injection----[1] 231
34ARO-AAT----[1] 231
35ARO-AAT Injection----[1] 231
36Aspirin[1] Acetylsalicylic acid[1] D00109 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[12] 13, 22, 34, 46, 49, 51, 58, 86, 113, 158, 210, 231
37Belcesiran----[1] 231
38Blood draw----[5] 6, 19, 65, 231, 299
39Blood draw.----[2] 231, 299
40Carbamazepine[1] Carbamazepine[1] D00252 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[2] 13, 231
41Dose of 60 mg/kg alpha1-proteinase inhibitor[1] Alpha-1-proteinase inhibitor---[1] 231
42Dose of 60 mg/kg Fraction IV-1 Alpha1-Proteinase Inhibitor[1] Alpha-1-proteinase inhibitor---[1] 231
43Drug-Carbamazepine (Tegretol XR)[1] Carbamazepine[1] D00252 [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 231
44Fentanyl[1] Fentanyl[2] D00320 ,
D01399 		[1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[4] 46, 70, 215, 231
45Glassia[1] Alpha-1-proteinase inhibitor---[1] 231
46History and physical----[1] 231
47History and physical exam.----[2] 231, 299
48Hyaluronic acid[1] Hyaluronic acid[1] D08043 --[5] 46, 53, 70, 226, 231
49Hyaluronic Acid Inhalation Solution[1] Hyaluronic acid[1] D08043 --[1] 231
50INBRX-101/rhAAT-Fc----[1] 231
51Intravenous catheter----[1] 231
52Kamada -AAT for Inhalation or inhaled AAT (AAT)----[1] 231
53Kamada-AAT for inhalation----[1] 231
54Kamada-AAT for Inhalation, 160mg----[1] 231
55Kamada-AAT for Inhalation, 80mg----[1] 231
56Kamada-API----[1] 231
57Lidocaine[1] Lidocaine[3] D00358 ,
D02086 ,
D08127 		[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[12] 6, 13, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256
58Liver biopsy----[4] 93, 171, 231, 240
59Lorazepam[1] Lorazepam[1] D00365 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[2] 36, 231
60Midazolam[1] Midazolam[3] D00550 ,
D00696 ,
D05028 		[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
61MPH966----[2] 228, 231
62None----[16] 6, 46, 51, 65, 78, 84, 85, 96, 97, 140, 160, 161, 171, 231, 271, 299
63None assigned[1] Interleukin-1 alpha, human recombinant---[2] 231, 299
64OctaAlpha1----[1] 231
65Ondansetron[1] Ondansetron[2] D00456 ,
D00678 		[5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		[2] Serotonergic synapse, Taste transduction 💬[4] 6, 97, 107, 231
66Other: Liver questionnaire----[1] 231
67Other: Sterile Normal Saline (0.9% NaCl)----[1] 231
68Other: Withdrawal from alpha1 antitrypsin replacement therapy----[1] 231
69Oxycodone[1] Oxycodone[3] D03783 ,
D05312 ,
D05462 		[3] OPRD1,
OPRK1,
OPRM1 💬		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 13, 46, 70, 226, 231, 298
70Oxycodone/Acetaminophen[1] Acetaminophen[1] D00217 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 231
71PBA----[1] 231
72PHP-303----[1] 231
73Prolastin----[3] 231, 298, 299
74Prolastin-C[1] Alpha-1-proteinase inhibitor---[2] 231, 298
75Prolastin-C, 120 mg/kg[1] Alpha-1-proteinase inhibitor---[1] 231
76Prolastin-C, 60 mg/kg[1] Alpha-1-proteinase inhibitor---[1] 231
77Pulmonary function testing.----[2] 231, 299
78RAAV1-CB-hAAT----[1] 231
79RECOMBINANT ADENO-ASSOCIATED VIRAL VECTOR EXPRESSING THE HUMAN ALPHA-1-ANTITRYPSIN GENE[1] Alpha-1-proteinase inhibitor---[1] 231
80Retinoic acid[1] Tretinoin[1] D00094 [3] PML,
RARA,
RARB 💬		[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[2] 94, 231
81Retinoic Acid Receptor gamma Agonist[1] Tretinoin[1] D00094 [3] PML,
RARA,
RARB 💬		[12] Acute myeloid leukemia, Endocytosis, Estrogen signaling pathway, Gastric cancer, Herpes simplex virus 1 infection, Influenza A, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer, Ubiquitin mediated proteolysis 💬[1] 231
82RO3300074----[1] 231
83VX-814----[1] 231
84VX-864----[1] 231
85VX864----[1] 231