Drug Description in Trials / DrugBank / KEGG DRUG /

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(S)-4,5-dihydro-2-[2-hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazo----[1] 284
2(S)-4,5-dihydro-2-[2-hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylate magnesium hydroxide[3] Hydroxide ion,
Magnesium,
Magnesium hydroxide		[1] D00731 --[1] 284
3(S)-4,5-dihydro-2[hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-m----[1] 284
4(S)-4,5-dihydro-2[hydroxy-3-(3,6,9-trioxadecyloxy)phenyl]-4-methyl-4-thiazolecarboxylate magnesium hydroxide[3] Hydroxide ion,
Magnesium,
Magnesium hydroxide		[1] D00731 --[1] 284
5Abatacept[1] Abatacept[1] D03203 [2] CD80,
CD86 💬		[12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis 💬[26] 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300
6Alefacept[1] Alefacept[1] D02800 [1] CD58 💬[2] Cell adhesion molecules, Epstein-Barr virus infection 💬[6] 37, 60, 65, 164, 284, 285
7ALEMTUZUMAB[1] Alemtuzumab[1] D02802 [1] CD52 💬-[17] 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 63, 65, 85, 96, 164, 283, 284
8Allogeneic Bone Marrow Transplantation----[9] 60, 62, 65, 96, 164, 283, 284, 285, 286
9Allogeneic hematopoietic stem cell transplantation----[8] 28, 51, 60, 62, 65, 164, 284, 285
10Alpha beta depletion----[2] 60, 284
11Anti-Thymocyte Globulin----[18] 11, 13, 14, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 164, 283, 284, 285
12Antithymocyte Globulin----[3] 60, 65, 284
13Bone marrow transplantation----[4] 51, 60, 284, 285
14BPX-501 T cells----[4] 65, 284, 285, 326
15Busulfan[1] Busulfan[1] D00248 --[13] 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326
16Busulfan, Cyclophosphamide, ATG, GCSF[2] Busulfan,
Cyclophosphamide		[3] D00248 ,
D00287 ,
D07760 		--[2] 65, 284
17Busulfan, Fludarabine, ATG, TLI[2] Busulfan,
Fludarabine		[3] D00248 ,
D01907 ,
D07966 		[1] RRM1 💬[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬[2] 65, 284
18Campath, Fludarabine, Cyclophosphamide[2] Cyclophosphamide,
Fludarabine		[4] D00287 ,
D01907 ,
D07760 ,
D07966 		[1] RRM1 💬[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬[2] 65, 284
19CD3/CD19 depleted leukocytes----[1] 284
20CD34 Stem Cell Selection Therapy----[3] 60, 65, 284
21CD45RA depleted leukocytes----[1] 284
22Cyclophosphamide[1] Cyclophosphamide[2] D00287 ,
D07760 		--[45] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331
23Cyclophosphamide Dose Level 1[1] Cyclophosphamide[2] D00287 ,
D07760 		--[2] 65, 284
24Cyclophosphamide Dose Level 2[1] Cyclophosphamide[2] D00287 ,
D07760 		--[2] 65, 284
25Cyclophosphamide Dose Level 3[1] Cyclophosphamide[2] D00287 ,
D07760 		--[2] 65, 284
26Cyclophosphamide Dose Level 4[1] Cyclophosphamide[2] D00287 ,
D07760 		--[2] 65, 284
27Cyclosporine[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[37] 11, 19, 20, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 107, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302
28DACLIZUMAB[1] Daclizumab[1] D03639 [1] IL2RA 💬[11] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[8] 13, 56, 60, 65, 97, 107, 283, 284
29Deferasirox[1] Deferasirox[1] D03669 --[3] 254, 284, 286
30Deferitazole[1] Deferitazole[1] D10388 --[1] 284
31Deferoxamine[1] Deferoxamine[2] D01186 ,
D03670 		--[2] 284, 286
32Desferal[1] Deferoxamine[2] D01186 ,
D03670 		--[2] 284, 286
33DFO----[3] 46, 284, 286
34ELTROMBOPAG[1] Eltrombopag---[5] 60, 63, 65, 284, 285
35Enriched Hematopoetic Stem Cell Infusion----[3] 13, 19, 284
36Exjade[1] Deferasirox[1] D03669 --[3] 254, 284, 286
37FBS0701----[1] 284
38FBS0701 CAPSULE----[1] 284
39FBS0701/SSP004184----[1] 284
40Filgrastim[1] Filgrastim[1] D03235 [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[28] 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331
41Fludarabine[1] Fludarabine[2] D01907 ,
D07966 		[1] RRM1 💬[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬[18] 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326
42Fludarabine monophosphate[1] Fludarabine[2] D01907 ,
D07966 		[1] RRM1 💬[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬[3] 65, 284, 326
43Fludarabine phosphate[2] Fludarabine,
Phosphate ion		[2] D01907 ,
D07966 		[1] RRM1 💬[5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism 💬[12] 28, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286
44G-CSF[1] Filgrastim[1] D03235 [1] CSF3R 💬[5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[16] 2, 6, 11, 13, 16, 47, 49, 51, 60, 62, 65, 85, 96, 284, 285, 331
45Human Placental Derived Stem Cell----[4] 19, 20, 60, 284
46Hydroxide[1] Hydroxide ion---[5] 11, 46, 96, 97, 284
47Hydroxyurea[1] Hydroxyurea[1] D00341 [1] RRM2 💬[6] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[8] 3, 13, 19, 20, 65, 85, 86, 284
48ICL670----[3] 60, 284, 286
49Iron[1] Iron---[6] 18, 96, 97, 238, 254, 284
50IRON CHELATING AGENTS----[1] 284
51L-leucine[1] Leucine[1] D00030 --[1] 284
52Lenalidomide[1] Lenalidomide[1] D04687 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[8] 16, 26, 28, 34, 49, 284, 300, 331
53Leucine[1] Leucine[1] D00030 --[11] 5, 6, 7, 19, 65, 96, 97, 127, 283, 284, 299
54Leukapheresis----[5] 49, 51, 96, 284, 285
55Magnesium[1] Magnesium---[19] 3, 6, 11, 13, 15, 46, 64, 70, 93, 97, 166, 225, 235, 256, 284, 291, 296, 297, 298
56Magnesium hydroxide[3] Hydroxide ion,
Magnesium,
Magnesium hydroxide		[1] D00731 --[1] 284
57Melphalan[1] Melphalan[1] D00369 --[15] 11, 13, 14, 19, 20, 28, 60, 62, 65, 96, 164, 234, 284, 285, 299
58Mesenchymal Stromal Cells[1] Human Umbilical Cord Mesenchymal Stem Cells---[10] 2, 36, 49, 51, 60, 96, 97, 107, 274, 284
59Methotrexate[1] Methotrexate[2] D00142 ,
D02115 		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[38] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331
60Methylprednisolone[1] Methylprednisolone[6] D00407 ,
D00751 ,
D00979 ,
D05000 ,
D05001 ,
D05002 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 86, 93, 95, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300
61Mycophenolate[1] Mycophenolic acid[1] D05096 [2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
62Mycophenolate mofetil[2] Mycophenolate mofetil,
Mycophenolic acid		[4] D00752 ,
D05094 ,
D05095 ,
D05096 		[2] IMPDH1,
IMPDH2 💬		[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism 💬[34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
63Myeloablative Preparative Regimen----[3] 62, 65, 284
64Other: Laboratory Biomarker Analysis----[21] 11, 13, 14, 26, 28, 34, 49, 51, 60, 62, 65, 89, 96, 97, 205, 232, 283, 284, 285, 298, 331
65Peripheral Blood Stem Cell Transplantation----[12] 11, 13, 14, 28, 51, 60, 62, 65, 283, 284, 285, 286
66Phosphate[1] Phosphate ion---[33] 2, 3, 6, 11, 12, 13, 15, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 238, 256, 276, 283, 284, 285, 286, 299
67Prednisone[1] Prednisone[1] D00473 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[48] 2, 6, 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 127, 162, 164, 205, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331
68Radiation therapy----[3] 13, 284, 285
69Radiation: radiation therapy----[5] 34, 60, 65, 284, 285
70Radiation: Total Body Irradiation----[7] 36, 49, 51, 60, 65, 283, 284
71Radiation: total-body irradiation----[9] 28, 51, 60, 62, 65, 96, 283, 284, 285
72Reduced Intensity Preparative Regimen----[3] 62, 65, 284
73Reduced Toxicity Ablative Regimen----[3] 62, 65, 284
74Rimiducid[1] Rimiducid[1] D11195 [1] CASP9 💬[35] Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platinum drug resistance, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬[6] 19, 60, 65, 284, 285, 326
75Rituximab[1] Rituximab[1] D02994 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[49] 6, 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 127, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
76Rivogenlecleucel----[6] 19, 60, 65, 284, 285, 326
77SOTATERCEPT[1] Sotatercept[1] D09670 [1] ACVR2A 💬[4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[2] 86, 284
78Sotatercept with prednisone boost[2] Prednisone,
Sotatercept		[2] D00473 ,
D09670 		[2] ACVR2A,
NR3C1 💬		[5] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Neuroactive ligand-receptor interaction, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[1] 284
79SSP-004184 100 mg----[1] 284
80SSP-004184 100 mg Capsule----[1] 284
81SSP-004184 250 mg----[1] 284
82SSP-004184 250 mg Capsule----[1] 284
83SSP-004184 375 mg----[1] 284
84SSP-004184 375 mg Capsule----[1] 284
85SSP-004184 50 mg----[1] 284
86SSP-004184 50 mg Capsule----[1] 284
87SSP-004184 500 mg----[1] 284
88SSP-004184 500 mg Capsule----[1] 284
89SSP-004184AQ 100 mg----[1] 284
90SSP-004184AQ 100 mg Capsule----[1] 284
91SSP-004184AQ 200 mg----[1] 284
92SSP-004184AQ 200 mg Capsule----[1] 284
93SSP-004184AQ 250 mg----[1] 284
94SSP-004184AQ 250 mg Capsule----[1] 284
95SSP-004184AQ 375 mg----[1] 284
96SSP-004184AQ 375 mg Capsule----[1] 284
97SSP-004184AQ 50 mg----[1] 284
98SSP-004184AQ 50 mg Capsule----[1] 284
99Stem Cell Infusion----[5] 28, 60, 65, 284, 285
100Stem Cell Transplant----[6] 19, 20, 60, 65, 164, 284
101Tacrolimus[1] Tacrolimus[2] D00107 ,
D08556 		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
102Thiotepa[1] Thiotepa[1] D00583 --[12] 13, 19, 20, 28, 51, 60, 65, 85, 96, 164, 284, 285
103Thiotepa--escalated dose[1] Thiotepa[1] D00583 --[4] 19, 20, 65, 284
104Thiotepa--single daily dose[1] Thiotepa[1] D00583 --[4] 19, 20, 65, 284
105Total lymphoid irradiation----[3] 65, 284, 326
106Trifluoperazine[1] Trifluoperazine[3] D00799 ,
D01448 ,
D08636 		[1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 283, 284
107Umbilical Cord Blood Transplantation----[5] 60, 65, 284, 285, 326