| 1 | Amitriptyline, fluoxetine and tramadol alone (control group) | [3] AmitriptylineAmitriptyline, Fluoxetine,
 Tramadol
 | [6] D00326D00326
                
             (Name: Fluoxetine), D00809
                
            ,
 D00823
                
             (Name: Fluoxetine hydrochloride),
 D01355
                
            ,
 D07448
                
            ,
 D08623
 | [3] OPRM1OPRM1, SLC6A2,
 SLC6A4 💬
 | [5] Estrogen signaling pathwayEstrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬 | [1] 7878 | 
| 2 | FLUOXETINE | [1] FluoxetineFluoxetine | [2] D00326D00326
                
             (Name: Fluoxetine), D00823
                
             (Name: Fluoxetine hydrochloride)
 | [1] SLC6A4SLC6A4 💬 | [2] Serotonergic synapseSerotonergic synapse, Synaptic vesicle cycle 💬 | [4] 1313, 17, 78, 86 | 
| 3 | FLUOXETINE HYDROCHLORIDE | [1] FluoxetineFluoxetine | [2] D00326D00326
                
             (Name: Fluoxetine), D00823
                
             (Name: Fluoxetine hydrochloride)
 | [1] SLC6A4SLC6A4 💬 | [2] Serotonergic synapseSerotonergic synapse, Synaptic vesicle cycle 💬 | [1] 1313 | 
| 4 | Sc recombinant growth hormone + amitriptyline, fluoxetine and tramadol (treated group) | [4] AmitriptylineAmitriptyline, Fluoxetine,
 Somatotropin,
 Tramadol
 | [7] D00326D00326
                
             (Name: Fluoxetine), D00809
                
            ,
 D00823
                
             (Name: Fluoxetine hydrochloride),
 D01355
                
            ,
 D02691
                
            ,
 D07448
                
            ,
 D08623
 | [4] GHRGHR, OPRM1,
 SLC6A2,
 SLC6A4 💬
 | [9] Cytokine-cytokine receptor interactionCytokine-cytokine receptor interaction, Estrogen signaling pathway, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Serotonergic synapse, Synaptic vesicle cycle 💬 | [1] 7878 |