KEGG DRUG

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No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY	Disease ID
1	Elexacaftor-tezacaftor-ivacaftor exposure	[3] Elexacaftor, Ivacaftor, Tezacaftor	[3] D09916 , D11041 (Name: Tezacaftor), D11507	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299
2	Elexacaftor/tezacaftor/ivacaftor	[3] Elexacaftor, Ivacaftor, Tezacaftor	[3] D09916 , D11041 (Name: Tezacaftor), D11507	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299
3	Ivacaftor or elexacaftor/tezacaftor/ivacaftor	[3] Elexacaftor, Ivacaftor, Tezacaftor	[3] D09916 , D11041 (Name: Tezacaftor), D11507	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299
4	TEZACAFTOR	[1] Tezacaftor	[1] D11041 (Name: Tezacaftor)	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299
5	Tezacaftor (TEZ)	[1] Tezacaftor	[1] D11041 (Name: Tezacaftor)	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299
6	Tezacaftor/Ivacaftor	[2] Ivacaftor, Tezacaftor	[2] D09916 , D11041 (Name: Tezacaftor)	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299
7	Tezacaftor/Ivacaftor + Ivacaftor	[2] Ivacaftor, Tezacaftor	[2] D09916 , D11041 (Name: Tezacaftor)	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299
8	Tezacaftor/Ivacaftor 100mg/150mg	[2] Ivacaftor, Tezacaftor	[2] D09916 , D11041 (Name: Tezacaftor)	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299
9	Tezacaftor/Ivacaftor/100mg/150mg	[2] Ivacaftor, Tezacaftor	[2] D09916 , D11041 (Name: Tezacaftor)	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299
10	Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor	[4] Elexacaftor, Ivacaftor, Lumacaftor, Tezacaftor	[4] D09916 , D10134 , D11041 (Name: Tezacaftor), D11507	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299
11	VX-121/tezacaftor/deutivacaftor	[2] Deutivacaftor, Tezacaftor	[2] D11041 (Name: Tezacaftor), D11423	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299
12	VX-659/Tezacaftor/Ivacaftor	[3] Ivacaftor, Tezacaftor, VX-659	[2] D09916 , D11041 (Name: Tezacaftor)	[1] CFTR 💬	[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬	[1] 299