Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 TPH2 [2] Tryptophan metabolism, Serotonergic synapse D09973 Telotristat [1] 97
2 DDC [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D00558 Carbidopa [9] 2, 4, 6, 13, 17, 90, 140, 164, 201
3 DDC [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D03082 Benserazide [1] 6
4 HTR3C [2] Serotonergic synapse, Taste transduction D00283 Clozapine [1] 6
5 HTR3C [2] Serotonergic synapse, Taste transduction D00456 Ondansetron [4] 6, 97, 107, 231
6 HTR3C [2] Serotonergic synapse, Taste transduction D00678 Ondansetron [4] 6, 97, 107, 231
7 HTR3C [2] Serotonergic synapse, Taste transduction D10184 Vortioxetine [1] 6
8 HTR3D [2] Serotonergic synapse, Taste transduction D00283 Clozapine [1] 6
9 HTR3D [2] Serotonergic synapse, Taste transduction D00456 Ondansetron [4] 6, 97, 107, 231
10 HTR3D [2] Serotonergic synapse, Taste transduction D00678 Ondansetron [4] 6, 97, 107, 231
11 HTR3D [2] Serotonergic synapse, Taste transduction D10184 Vortioxetine [1] 6
12 ALOX5 [2] Serotonergic synapse, Toxoplasmosis D00414 Zileuton [3] 85, 160, 164
13 ALOX5 [2] Serotonergic synapse, Toxoplasmosis D01773 Oxatomide [1] 113
14 GABRB1 [1] Serotonergic synapse D00225 Alprazolam [2] 8, 75
15 GABRB1 [1] Serotonergic synapse D00267 Chlordiazepoxide [1] 46
16 GABRB1 [1] Serotonergic synapse D00280 Clonazepam [1] 6
17 GABRB1 [1] Serotonergic synapse D00293 Diazepam [3] 46, 155, 298
18 GABRB1 [1] Serotonergic synapse D00365 Lorazepam [2] 36, 231
19 GABRB1 [1] Serotonergic synapse D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
20 GABRB1 [1] Serotonergic synapse D00549 Propofol [10] 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
21 GABRB1 [1] Serotonergic synapse D00550 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
22 GABRB1 [1] Serotonergic synapse D00693 Chlordiazepoxide [1] 46
23 GABRB1 [1] Serotonergic synapse D00696 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
24 GABRB1 [1] Serotonergic synapse D00697 Flumazenil [5] 6, 13, 17, 18, 206
25 GABRB1 [1] Serotonergic synapse D00706 Zolpidem [3] 5, 6, 46
26 GABRB1 [1] Serotonergic synapse D01253 Clobazam [2] 140, 144
27 GABRB1 [1] Serotonergic synapse D01372 Zopiclone [1] 6
28 GABRB1 [1] Serotonergic synapse D01514 Etizolam [1] 46
29 GABRB1 [1] Serotonergic synapse D02624 Eszopiclone [3] 6, 13, 46
30 GABRB1 [1] Serotonergic synapse D04282 Gaboxadol [2] 201, 206
31 GABRB1 [1] Serotonergic synapse D04300 Ganaxolone [4] 145, 152, 158, 206
32 GABRB1 [1] Serotonergic synapse D05028 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
33 GABRB1 [1] Serotonergic synapse D07784 Delorazepam [3] 6, 46, 97
34 GABRB1 [1] Serotonergic synapse D08690 Zolpidem [3] 5, 6, 46
35 GABRB1 [1] Serotonergic synapse D11149 Brexanolone [1] 205
36 GABRB2 [1] Serotonergic synapse D00225 Alprazolam [2] 8, 75
37 GABRB2 [1] Serotonergic synapse D00267 Chlordiazepoxide [1] 46
38 GABRB2 [1] Serotonergic synapse D00280 Clonazepam [1] 6
39 GABRB2 [1] Serotonergic synapse D00293 Diazepam [3] 46, 155, 298
40 GABRB2 [1] Serotonergic synapse D00365 Lorazepam [2] 36, 231
41 GABRB2 [1] Serotonergic synapse D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
42 GABRB2 [1] Serotonergic synapse D00549 Propofol [10] 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
43 GABRB2 [1] Serotonergic synapse D00550 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
44 GABRB2 [1] Serotonergic synapse D00693 Chlordiazepoxide [1] 46
45 GABRB2 [1] Serotonergic synapse D00696 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
46 GABRB2 [1] Serotonergic synapse D00697 Flumazenil [5] 6, 13, 17, 18, 206
47 GABRB2 [1] Serotonergic synapse D00706 Zolpidem [3] 5, 6, 46
48 GABRB2 [1] Serotonergic synapse D01253 Clobazam [2] 140, 144
49 GABRB2 [1] Serotonergic synapse D01372 Zopiclone [1] 6
50 GABRB2 [1] Serotonergic synapse D01514 Etizolam [1] 46
51 GABRB2 [1] Serotonergic synapse D02624 Eszopiclone [3] 6, 13, 46
52 GABRB2 [1] Serotonergic synapse D04282 Gaboxadol [2] 201, 206
53 GABRB2 [1] Serotonergic synapse D04300 Ganaxolone [4] 145, 152, 158, 206
54 GABRB2 [1] Serotonergic synapse D05028 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
55 GABRB2 [1] Serotonergic synapse D07784 Delorazepam [3] 6, 46, 97
56 GABRB2 [1] Serotonergic synapse D08690 Zolpidem [3] 5, 6, 46
57 GABRB2 [1] Serotonergic synapse D11149 Brexanolone [1] 205
58 GABRB3 [1] Serotonergic synapse D00225 Alprazolam [2] 8, 75
59 GABRB3 [1] Serotonergic synapse D00267 Chlordiazepoxide [1] 46
60 GABRB3 [1] Serotonergic synapse D00280 Clonazepam [1] 6
61 GABRB3 [1] Serotonergic synapse D00293 Diazepam [3] 46, 155, 298
62 GABRB3 [1] Serotonergic synapse D00365 Lorazepam [2] 36, 231
63 GABRB3 [1] Serotonergic synapse D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
64 GABRB3 [1] Serotonergic synapse D00549 Propofol [10] 6, 21, 22, 34, 46, 70, 75, 84, 98, 296
65 GABRB3 [1] Serotonergic synapse D00550 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
66 GABRB3 [1] Serotonergic synapse D00693 Chlordiazepoxide [1] 46
67 GABRB3 [1] Serotonergic synapse D00696 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
68 GABRB3 [1] Serotonergic synapse D00697 Flumazenil [5] 6, 13, 17, 18, 206
69 GABRB3 [1] Serotonergic synapse D00706 Zolpidem [3] 5, 6, 46
70 GABRB3 [1] Serotonergic synapse D01253 Clobazam [2] 140, 144
71 GABRB3 [1] Serotonergic synapse D01372 Zopiclone [1] 6
72 GABRB3 [1] Serotonergic synapse D01514 Etizolam [1] 46
73 GABRB3 [1] Serotonergic synapse D02624 Eszopiclone [3] 6, 13, 46
74 GABRB3 [1] Serotonergic synapse D04282 Gaboxadol [2] 201, 206
75 GABRB3 [1] Serotonergic synapse D04300 Ganaxolone [4] 145, 152, 158, 206
76 GABRB3 [1] Serotonergic synapse D05028 Midazolam [12] 2, 3, 6, 13, 21, 46, 70, 96, 97, 231, 272, 298
77 GABRB3 [1] Serotonergic synapse D07784 Delorazepam [3] 6, 46, 97
78 GABRB3 [1] Serotonergic synapse D08690 Zolpidem [3] 5, 6, 46
79 GABRB3 [1] Serotonergic synapse D11149 Brexanolone [1] 205
80 HTR3E [2] Serotonergic synapse, Taste transduction D00283 Clozapine [1] 6
81 HTR3E [2] Serotonergic synapse, Taste transduction D00456 Ondansetron [4] 6, 97, 107, 231
82 HTR3E [2] Serotonergic synapse, Taste transduction D00678 Ondansetron [4] 6, 97, 107, 231
83 HTR3E [2] Serotonergic synapse, Taste transduction D10184 Vortioxetine [1] 6
84 HTR1A [2] Serotonergic synapse, Taste transduction D00702 Buspirone [3] 6, 51, 179
85 HTR1A [2] Serotonergic synapse, Taste transduction D01164 Aripiprazole [2] 6, 206
86 HTR1A [2] Serotonergic synapse, Taste transduction D07593 Buspirone [3] 6, 51, 179
87 HTR1A [2] Serotonergic synapse, Taste transduction D09397 Pardoprunox [1] 6
88 HTR1A [2] Serotonergic synapse, Taste transduction D09997 Cariprazine [1] 21
89 HTR1A [2] Serotonergic synapse, Taste transduction D10184 Vortioxetine [1] 6
90 HTR1B [2] Serotonergic synapse, Taste transduction D00415 Zolmitriptan [1] 6
91 HTR1D [2] Serotonergic synapse, Taste transduction D00415 Zolmitriptan [1] 6
92 HTR2A [1] Serotonergic synapse D00270 Chlorpromazine [1] 254
93 HTR2A [1] Serotonergic synapse D00274 Cisapride [1] 13
94 HTR2A [1] Serotonergic synapse D00283 Clozapine [1] 6
95 HTR2A [1] Serotonergic synapse D00426 Risperidone [5] 8, 156, 179, 187, 206
96 HTR2A [1] Serotonergic synapse D00454 Olanzapine [2] 2, 8
97 HTR2A [1] Serotonergic synapse D00458 Quetiapine [2] 6, 13
98 HTR2A [1] Serotonergic synapse D00789 Chlorpromazine [1] 254
99 HTR2A [1] Serotonergic synapse D00820 Trazodone [1] 2
100 HTR2A [1] Serotonergic synapse D01164 Aripiprazole [2] 6, 206
101 HTR2A [1] Serotonergic synapse D02092 Cisapride [1] 13
102 HTR2A [1] Serotonergic synapse D03274 Chlorpromazine [1] 254
103 HTR2A [1] Serotonergic synapse D04034 Chlorpromazine [1] 254
104 HTR2A [1] Serotonergic synapse D06623 Olanzapine [2] 2, 8
105 HTR2A [1] Serotonergic synapse D07945 Fenfluramine [4] 140, 144, 145, 149
106 HTR2A [1] Serotonergic synapse D08456 Quetiapine [2] 6, 13
107 HTR2A [1] Serotonergic synapse D08626 Trazodone [1] 2
108 HTR2A [1] Serotonergic synapse D09645 Nelotanserin [1] 6
109 HTR2A [1] Serotonergic synapse D09997 Cariprazine [1] 21
110 HTR2B [1] Serotonergic synapse D00270 Chlorpromazine [1] 254
111 HTR2B [1] Serotonergic synapse D00454 Olanzapine [2] 2, 8
112 HTR2B [1] Serotonergic synapse D00789 Chlorpromazine [1] 254
113 HTR2B [1] Serotonergic synapse D00820 Trazodone [1] 2
114 HTR2B [1] Serotonergic synapse D03274 Chlorpromazine [1] 254
115 HTR2B [1] Serotonergic synapse D04034 Chlorpromazine [1] 254
116 HTR2B [1] Serotonergic synapse D06623 Olanzapine [2] 2, 8
117 HTR2B [1] Serotonergic synapse D07945 Fenfluramine [4] 140, 144, 145, 149
118 HTR2B [1] Serotonergic synapse D08626 Trazodone [1] 2
119 HTR2C [1] Serotonergic synapse D00270 Chlorpromazine [1] 254
120 HTR2C [1] Serotonergic synapse D00283 Clozapine [1] 6
121 HTR2C [1] Serotonergic synapse D00454 Olanzapine [2] 2, 8
122 HTR2C [1] Serotonergic synapse D00789 Chlorpromazine [1] 254
123 HTR2C [1] Serotonergic synapse D00820 Trazodone [1] 2
124 HTR2C [1] Serotonergic synapse D02578 Agomelatine [1] 6
125 HTR2C [1] Serotonergic synapse D03274 Chlorpromazine [1] 254
126 HTR2C [1] Serotonergic synapse D04034 Chlorpromazine [1] 254
127 HTR2C [1] Serotonergic synapse D06623 Olanzapine [2] 2, 8
128 HTR2C [1] Serotonergic synapse D07945 Fenfluramine [4] 140, 144, 145, 149
129 HTR2C [1] Serotonergic synapse D08626 Trazodone [1] 2
130 HTR3A [2] Serotonergic synapse, Taste transduction D00274 Cisapride [1] 13
131 HTR3A [2] Serotonergic synapse, Taste transduction D00283 Clozapine [1] 6
132 HTR3A [2] Serotonergic synapse, Taste transduction D00456 Ondansetron [4] 6, 97, 107, 231
133 HTR3A [2] Serotonergic synapse, Taste transduction D00678 Ondansetron [4] 6, 97, 107, 231
134 HTR3A [2] Serotonergic synapse, Taste transduction D02092 Cisapride [1] 13
135 HTR3A [2] Serotonergic synapse, Taste transduction D10184 Vortioxetine [1] 6
136 HTR4 [1] Serotonergic synapse D00274 Cisapride [1] 13
137 HTR4 [1] Serotonergic synapse D02092 Cisapride [1] 13
138 HTR4 [1] Serotonergic synapse D08236 Mosapride [1] 96
139 HTR4 [1] Serotonergic synapse D09205 Prucalopride [3] 13, 51, 96
140 HTR4 [1] Serotonergic synapse D09693 Velusetrag [1] 99
141 HTR6 [1] Serotonergic synapse D00454 Olanzapine [2] 2, 8
142 HTR6 [1] Serotonergic synapse D06623 Olanzapine [2] 2, 8
143 KCND2 [1] Serotonergic synapse D04127 Dalfampridine [5] 3, 4, 6, 13, 14
144 KCND2 [1] Serotonergic synapse D10228 Amifampridine [3] 3, 11, 12
145 KCNJ3 [1] Serotonergic synapse D00636 Amiodarone [2] 28, 127
146 KCNJ3 [1] Serotonergic synapse D02910 Amiodarone [2] 28, 127
147 KCNJ5 [1] Serotonergic synapse D00636 Amiodarone [2] 28, 127
148 KCNJ5 [1] Serotonergic synapse D02910 Amiodarone [2] 28, 127
149 MAOA [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D00505 Phenelzine [1] 6
150 MAOA [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D02561 Moclobemide [1] 6
151 MAOA [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D02579 Iproniazid [1] 6
152 MAOA [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D05458 Phentermine [1] 97
153 MAOA [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D05459 Phentermine [1] 97
154 MAOA [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D08349 Phenelzine [1] 6
155 MAOB [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D00505 Phenelzine [1] 6
156 MAOB [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D00785 Selegiline [1] 6
157 MAOB [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D02562 Rasagiline [7] 2, 5, 6, 13, 17, 58, 66
158 MAOB [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D02579 Iproniazid [1] 6
159 MAOB [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D03731 Selegiline [1] 6
160 MAOB [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D05458 Phentermine [1] 97
161 MAOB [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D05459 Phentermine [1] 97
162 MAOB [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D08349 Phenelzine [1] 6
163 MAOB [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D08469 Rasagiline [7] 2, 5, 6, 13, 17, 58, 66
164 MAOB [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D10158 Safinamide [2] 6, 17
165 MAOB [3] Tyrosine metabolism, Tryptophan metabolism, Serotonergic synapse D10829 Rasagiline [7] 2, 5, 6, 13, 17, 58, 66
166 MAP2K1 [11] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Thyroid hormone signaling pathway, Yersinia infection, Thyroid cancer D09666 Selumetinib [1] 34
167 MAP2K1 [11] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Thyroid hormone signaling pathway, Yersinia infection, Thyroid cancer D10175 Trametinib [4] 2, 34, 279, 280
168 MAP2K1 [11] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Thyroid hormone signaling pathway, Yersinia infection, Thyroid cancer D10405 Cobimetinib [1] 280
169 MAP2K1 [11] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Serotonergic synapse, Thyroid hormone signaling pathway, Yersinia infection, Thyroid cancer D10604 Binimetinib [1] 34
170 PTGS1 [1] Serotonergic synapse D00109 Acetylsalicylic acid [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251
171 PTGS1 [1] Serotonergic synapse D00118 Naproxen [4] 13, 46, 107, 271
172 PTGS1 [1] Serotonergic synapse D00120 Sulindac [1] 206
173 PTGS1 [1] Serotonergic synapse D00126 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299
174 PTGS1 [1] Serotonergic synapse D00132 Ketoprofen [1] 46
175 PTGS1 [1] Serotonergic synapse D00141 Indomethacin [3] 225, 271, 298
176 PTGS1 [1] Serotonergic synapse D00217 Acetaminophen [18] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
177 PTGS1 [1] Serotonergic synapse D00330 Flurbiprofen [3] 13, 21, 46
178 PTGS1 [1] Serotonergic synapse D00428 Salsalate [1] 5
179 PTGS1 [1] Serotonergic synapse D00813 Ketorolac [2] 70, 226
180 PTGS1 [1] Serotonergic synapse D00903 Diclofenac [5] 13, 34, 46, 78, 271
181 PTGS1 [1] Serotonergic synapse D00904 Diclofenac [5] 13, 34, 46, 78, 271
182 PTGS1 [1] Serotonergic synapse D01122 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299
183 PTGS1 [1] Serotonergic synapse D01183 Tolfenamic acid [1] 5
184 PTGS1 [1] Serotonergic synapse D01475 Flurbiprofen [3] 13, 21, 46
185 PTGS1 [1] Serotonergic synapse D01545 Aceclofenac [1] 46
186 PTGS1 [1] Serotonergic synapse D01565 Indomethacin [3] 225, 271, 298
187 PTGS1 [1] Serotonergic synapse D02110 Indomethacin [3] 225, 271, 298
188 PTGS1 [1] Serotonergic synapse D02290 Flurbiprofen [3] 13, 21, 46
189 PTGS1 [1] Serotonergic synapse D04490 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299
190 PTGS1 [1] Serotonergic synapse D06606 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299
191 PTGS1 [1] Serotonergic synapse D07816 Diclofenac [5] 13, 34, 46, 78, 271
192 PTGS1 [1] Serotonergic synapse D08104 Ketorolac [2] 70, 226
193 PTGS1 [1] Serotonergic synapse D08149 Loxoprofen [2] 46, 271
194 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D00109 Acetylsalicylic acid [15] 13, 22, 34, 46, 49, 51, 58, 86, 96, 97, 113, 158, 210, 231, 251
195 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D00118 Naproxen [4] 13, 46, 107, 271
196 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D00120 Sulindac [1] 206
197 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D00126 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299
198 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D00130 Diflunisal [1] 28
199 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D00132 Ketoprofen [1] 46
200 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D00141 Indomethacin [3] 225, 271, 298
201 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D00217 Acetaminophen [18] 3, 6, 11, 13, 34, 35, 46, 49, 51, 70, 86, 96, 222, 231, 256, 271, 300, 337
202 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D00315 Etodolac [1] 46
203 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D00330 Flurbiprofen [3] 13, 21, 46
204 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D00428 Salsalate [1] 5
205 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D00567 Celecoxib [10] 2, 3, 34, 46, 70, 89, 107, 161, 171, 271
206 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D00568 Rofecoxib [1] 46
207 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D00813 Ketorolac [2] 70, 226
208 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D00903 Diclofenac [5] 13, 34, 46, 78, 271
209 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D00904 Diclofenac [5] 13, 34, 46, 78, 271
210 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D00969 Meloxicam [4] 46, 49, 271, 296
211 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D01049 Nimesulide [1] 46
212 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D01122 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299
213 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D01183 Tolfenamic acid [1] 5
214 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D01475 Flurbiprofen [3] 13, 21, 46
215 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D01545 Aceclofenac [1] 46
216 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D01565 Indomethacin [3] 225, 271, 298
217 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D02110 Indomethacin [3] 225, 271, 298
218 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D02290 Flurbiprofen [3] 13, 21, 46
219 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D02709 Valdecoxib [1] 46
220 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D03710 Etoricoxib [2] 46, 271
221 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D03714 Lumiracoxib [1] 46
222 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D03716 Parecoxib [2] 46, 271
223 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D04490 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299
224 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D06606 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299
225 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D07816 Diclofenac [5] 13, 34, 46, 78, 271
226 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D08104 Ketorolac [2] 70, 226
227 PTGS2 [4] VEGF signaling pathway, TNF signaling pathway, Serotonergic synapse, Small cell lung cancer D08149 Loxoprofen [2] 46, 271
228 RAF1 [8] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Thyroid hormone signaling pathway, Tuberculosis D06272 Sorafenib [2] 34, 86
229 RAF1 [8] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Serotonergic synapse, Thyroid hormone signaling pathway, Tuberculosis D08524 Sorafenib [2] 34, 86
230 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D00228 Amoxapine [1] 46
231 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D00326 Fluoxetine [6] 13, 17, 78, 86, 179, 206
232 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D00809 Amitriptyline [4] 78, 97, 226, 299
233 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D00812 Desipramine [2] 120, 156
234 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D00814 Doxepin [1] 6
235 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D00816 Nortriptyline [2] 6, 226
236 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D00820 Trazodone [1] 2
237 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D00821 Venlafaxine [3] 6, 13, 46
238 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D00822 Citalopram [7] 6, 8, 13, 18, 46, 98, 127
239 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D00823 Fluoxetine [6] 13, 17, 78, 86, 179, 206
240 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D00825 Sertraline [2] 6, 206
241 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D01179 Duloxetine [2] 6, 13
242 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D02260 Paroxetine [4] 6, 13, 46, 85
243 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D02360 Sertraline [2] 6, 206
244 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D02362 Paroxetine [4] 6, 13, 46, 85
245 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D02567 Escitalopram [3] 2, 6, 13
246 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D05374 Paroxetine [4] 6, 13, 46, 85
247 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D05375 Paroxetine [4] 6, 13, 46, 85
248 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D05458 Phentermine [1] 97
249 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D05459 Phentermine [1] 97
250 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D07448 Amitriptyline [4] 78, 97, 226, 299
251 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D07704 Citalopram [7] 6, 8, 13, 18, 46, 98, 127
252 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D07704 Escitalopram [3] 2, 6, 13
253 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D07791 Desipramine [2] 120, 156
254 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D07875 Doxepin [1] 6
255 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D07880 Duloxetine [2] 6, 13
256 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D07913 Escitalopram [3] 2, 6, 13
257 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D07945 Fenfluramine [4] 140, 144, 145, 149
258 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D08222 Milnacipran [2] 46, 49
259 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D08288 Nortriptyline [2] 6, 226
260 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D08626 Trazodone [1] 2
261 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D08670 Venlafaxine [3] 6, 13, 46
262 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D10184 Vortioxetine [1] 6
263 SLC6A4 [2] Synaptic vesicle cycle, Serotonergic synapse D11688 Ampreloxetine [2] 6, 17
264 SLC18A2 [2] Synaptic vesicle cycle, Serotonergic synapse D08575 Tetrabenazine [1] 8
265 SLC18A2 [2] Synaptic vesicle cycle, Serotonergic synapse D10675 Valbenazine [1] 8
266 SLC18A2 [2] Synaptic vesicle cycle, Serotonergic synapse D10701 Deutetrabenazine [1] 8
267 BRAF [3] Vascular smooth muscle contraction, Serotonergic synapse, Thyroid cancer D06272 Sorafenib [2] 34, 86
268 BRAF [3] Vascular smooth muscle contraction, Serotonergic synapse, Thyroid cancer D08524 Sorafenib [2] 34, 86
269 BRAF [3] Vascular smooth muscle contraction, Serotonergic synapse, Thyroid cancer D10064 Dabrafenib [1] 34
270 TPH1 [2] Tryptophan metabolism, Serotonergic synapse D09973 Telotristat [1] 97
271 CACNA1B [3] Synaptic vesicle cycle, Serotonergic synapse, Type II diabetes mellitus D01173 Cilnidipine [1] 67
272 CACNA1C [4] Vascular smooth muscle contraction, Serotonergic synapse, Taste transduction, Type II diabetes mellitus D00349 Isradipine [1] 6
273 CACNA1C [4] Vascular smooth muscle contraction, Serotonergic synapse, Taste transduction, Type II diabetes mellitus D00437 Nifedipine [2] 50, 81
274 CACNA1C [4] Vascular smooth muscle contraction, Serotonergic synapse, Taste transduction, Type II diabetes mellitus D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
275 CACNA1C [4] Vascular smooth muscle contraction, Serotonergic synapse, Taste transduction, Type II diabetes mellitus D00615 Amlodipine [4] 13, 51, 67, 298
276 CACNA1C [4] Vascular smooth muscle contraction, Serotonergic synapse, Taste transduction, Type II diabetes mellitus D00616 Diltiazem [3] 51, 58, 86
277 CACNA1C [4] Vascular smooth muscle contraction, Serotonergic synapse, Taste transduction, Type II diabetes mellitus D00617 Nicardipine [2] 70, 86
278 CACNA1C [4] Vascular smooth muscle contraction, Serotonergic synapse, Taste transduction, Type II diabetes mellitus D00619 Verapamil [3] 96, 140, 167
279 CACNA1C [4] Vascular smooth muscle contraction, Serotonergic synapse, Taste transduction, Type II diabetes mellitus D01173 Cilnidipine [1] 67
280 CACNA1C [4] Vascular smooth muscle contraction, Serotonergic synapse, Taste transduction, Type II diabetes mellitus D01908 Nilvadipine [1] 90
281 CACNA1C [4] Vascular smooth muscle contraction, Serotonergic synapse, Taste transduction, Type II diabetes mellitus D02356 Verapamil [3] 96, 140, 167
282 CACNA1C [4] Vascular smooth muscle contraction, Serotonergic synapse, Taste transduction, Type II diabetes mellitus D02914 Amlodipine [4] 13, 51, 67, 298
283 CACNA1C [4] Vascular smooth muscle contraction, Serotonergic synapse, Taste transduction, Type II diabetes mellitus D03830 Diltiazem [3] 51, 58, 86
284 CACNA1C [4] Vascular smooth muscle contraction, Serotonergic synapse, Taste transduction, Type II diabetes mellitus D05442 Perhexiline [2] 58, 272
285 CACNA1C [4] Vascular smooth muscle contraction, Serotonergic synapse, Taste transduction, Type II diabetes mellitus D07450 Amlodipine [4] 13, 51, 67, 298
286 CACNA1C [4] Vascular smooth muscle contraction, Serotonergic synapse, Taste transduction, Type II diabetes mellitus D07845 Diltiazem [3] 51, 58, 86
287 CACNA1C [4] Vascular smooth muscle contraction, Serotonergic synapse, Taste transduction, Type II diabetes mellitus D08270 Nicardipine [2] 70, 86
288 CACNA1C [4] Vascular smooth muscle contraction, Serotonergic synapse, Taste transduction, Type II diabetes mellitus D08340 Perhexiline [2] 58, 272
289 CACNA1C [4] Vascular smooth muscle contraction, Serotonergic synapse, Taste transduction, Type II diabetes mellitus D08441 Propiverine [1] 226
290 CACNA1D [4] Vascular smooth muscle contraction, Tight junction, Serotonergic synapse, Type II diabetes mellitus D00349 Isradipine [1] 6
291 CACNA1D [4] Vascular smooth muscle contraction, Tight junction, Serotonergic synapse, Type II diabetes mellitus D00437 Nifedipine [2] 50, 81
292 CACNA1D [4] Vascular smooth muscle contraction, Tight junction, Serotonergic synapse, Type II diabetes mellitus D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
293 CACNA1D [4] Vascular smooth muscle contraction, Tight junction, Serotonergic synapse, Type II diabetes mellitus D00615 Amlodipine [4] 13, 51, 67, 298
294 CACNA1D [4] Vascular smooth muscle contraction, Tight junction, Serotonergic synapse, Type II diabetes mellitus D00616 Diltiazem [3] 51, 58, 86
295 CACNA1D [4] Vascular smooth muscle contraction, Tight junction, Serotonergic synapse, Type II diabetes mellitus D00617 Nicardipine [2] 70, 86
296 CACNA1D [4] Vascular smooth muscle contraction, Tight junction, Serotonergic synapse, Type II diabetes mellitus D00619 Verapamil [3] 96, 140, 167
297 CACNA1D [4] Vascular smooth muscle contraction, Tight junction, Serotonergic synapse, Type II diabetes mellitus D01173 Cilnidipine [1] 67
298 CACNA1D [4] Vascular smooth muscle contraction, Tight junction, Serotonergic synapse, Type II diabetes mellitus D01908 Nilvadipine [1] 90
299 CACNA1D [4] Vascular smooth muscle contraction, Tight junction, Serotonergic synapse, Type II diabetes mellitus D02356 Verapamil [3] 96, 140, 167
300 CACNA1D [4] Vascular smooth muscle contraction, Tight junction, Serotonergic synapse, Type II diabetes mellitus D02914 Amlodipine [4] 13, 51, 67, 298
301 CACNA1D [4] Vascular smooth muscle contraction, Tight junction, Serotonergic synapse, Type II diabetes mellitus D03830 Diltiazem [3] 51, 58, 86
302 CACNA1D [4] Vascular smooth muscle contraction, Tight junction, Serotonergic synapse, Type II diabetes mellitus D05442 Perhexiline [2] 58, 272
303 CACNA1D [4] Vascular smooth muscle contraction, Tight junction, Serotonergic synapse, Type II diabetes mellitus D07450 Amlodipine [4] 13, 51, 67, 298
304 CACNA1D [4] Vascular smooth muscle contraction, Tight junction, Serotonergic synapse, Type II diabetes mellitus D07845 Diltiazem [3] 51, 58, 86
305 CACNA1D [4] Vascular smooth muscle contraction, Tight junction, Serotonergic synapse, Type II diabetes mellitus D08270 Nicardipine [2] 70, 86
306 CACNA1D [4] Vascular smooth muscle contraction, Tight junction, Serotonergic synapse, Type II diabetes mellitus D08340 Perhexiline [2] 58, 272
307 CACNA1D [4] Vascular smooth muscle contraction, Tight junction, Serotonergic synapse, Type II diabetes mellitus D08441 Propiverine [1] 226
308 CACNA1F [2] Vascular smooth muscle contraction, Serotonergic synapse D00349 Isradipine [1] 6
309 CACNA1F [2] Vascular smooth muscle contraction, Serotonergic synapse D00437 Nifedipine [2] 50, 81
310 CACNA1F [2] Vascular smooth muscle contraction, Serotonergic synapse D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
311 CACNA1F [2] Vascular smooth muscle contraction, Serotonergic synapse D00615 Amlodipine [4] 13, 51, 67, 298
312 CACNA1F [2] Vascular smooth muscle contraction, Serotonergic synapse D00616 Diltiazem [3] 51, 58, 86
313 CACNA1F [2] Vascular smooth muscle contraction, Serotonergic synapse D00617 Nicardipine [2] 70, 86
314 CACNA1F [2] Vascular smooth muscle contraction, Serotonergic synapse D00619 Verapamil [3] 96, 140, 167
315 CACNA1F [2] Vascular smooth muscle contraction, Serotonergic synapse D01173 Cilnidipine [1] 67
316 CACNA1F [2] Vascular smooth muscle contraction, Serotonergic synapse D01908 Nilvadipine [1] 90
317 CACNA1F [2] Vascular smooth muscle contraction, Serotonergic synapse D02356 Verapamil [3] 96, 140, 167
318 CACNA1F [2] Vascular smooth muscle contraction, Serotonergic synapse D02914 Amlodipine [4] 13, 51, 67, 298
319 CACNA1F [2] Vascular smooth muscle contraction, Serotonergic synapse D03830 Diltiazem [3] 51, 58, 86
320 CACNA1F [2] Vascular smooth muscle contraction, Serotonergic synapse D05442 Perhexiline [2] 58, 272
321 CACNA1F [2] Vascular smooth muscle contraction, Serotonergic synapse D07450 Amlodipine [4] 13, 51, 67, 298
322 CACNA1F [2] Vascular smooth muscle contraction, Serotonergic synapse D07845 Diltiazem [3] 51, 58, 86
323 CACNA1F [2] Vascular smooth muscle contraction, Serotonergic synapse D08270 Nicardipine [2] 70, 86
324 CACNA1F [2] Vascular smooth muscle contraction, Serotonergic synapse D08340 Perhexiline [2] 58, 272
325 CACNA1F [2] Vascular smooth muscle contraction, Serotonergic synapse D08441 Propiverine [1] 226
326 CACNA1S [2] Vascular smooth muscle contraction, Serotonergic synapse D00349 Isradipine [1] 6
327 CACNA1S [2] Vascular smooth muscle contraction, Serotonergic synapse D00437 Nifedipine [2] 50, 81
328 CACNA1S [2] Vascular smooth muscle contraction, Serotonergic synapse D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
329 CACNA1S [2] Vascular smooth muscle contraction, Serotonergic synapse D00615 Amlodipine [4] 13, 51, 67, 298
330 CACNA1S [2] Vascular smooth muscle contraction, Serotonergic synapse D00616 Diltiazem [3] 51, 58, 86
331 CACNA1S [2] Vascular smooth muscle contraction, Serotonergic synapse D00617 Nicardipine [2] 70, 86
332 CACNA1S [2] Vascular smooth muscle contraction, Serotonergic synapse D00619 Verapamil [3] 96, 140, 167
333 CACNA1S [2] Vascular smooth muscle contraction, Serotonergic synapse D01173 Cilnidipine [1] 67
334 CACNA1S [2] Vascular smooth muscle contraction, Serotonergic synapse D01908 Nilvadipine [1] 90
335 CACNA1S [2] Vascular smooth muscle contraction, Serotonergic synapse D02356 Verapamil [3] 96, 140, 167
336 CACNA1S [2] Vascular smooth muscle contraction, Serotonergic synapse D02914 Amlodipine [4] 13, 51, 67, 298
337 CACNA1S [2] Vascular smooth muscle contraction, Serotonergic synapse D03830 Diltiazem [3] 51, 58, 86
338 CACNA1S [2] Vascular smooth muscle contraction, Serotonergic synapse D05442 Perhexiline [2] 58, 272
339 CACNA1S [2] Vascular smooth muscle contraction, Serotonergic synapse D07450 Amlodipine [4] 13, 51, 67, 298
340 CACNA1S [2] Vascular smooth muscle contraction, Serotonergic synapse D07845 Diltiazem [3] 51, 58, 86
341 CACNA1S [2] Vascular smooth muscle contraction, Serotonergic synapse D08270 Nicardipine [2] 70, 86
342 CACNA1S [2] Vascular smooth muscle contraction, Serotonergic synapse D08340 Perhexiline [2] 58, 272
343 CACNA1S [2] Vascular smooth muscle contraction, Serotonergic synapse D08441 Propiverine [1] 226
344 HTR3B [2] Serotonergic synapse, Taste transduction D00283 Clozapine [1] 6
345 HTR3B [2] Serotonergic synapse, Taste transduction D00456 Ondansetron [4] 6, 97, 107, 231
346 HTR3B [2] Serotonergic synapse, Taste transduction D00678 Ondansetron [4] 6, 97, 107, 231
347 HTR3B [2] Serotonergic synapse, Taste transduction D10184 Vortioxetine [1] 6