Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 CDK4 [2] Tight junction, Viral carcinogenesis D10688 Abemaciclib [1] 34
2 CFTR [2] Tight junction, Vibrio cholerae infection D09916 Ivacaftor [1] 299
3 CFTR [2] Tight junction, Vibrio cholerae infection D10134 Lumacaftor [1] 299
4 CFTR [2] Tight junction, Vibrio cholerae infection D11041 Tezacaftor [1] 299
5 CFTR [2] Tight junction, Vibrio cholerae infection D11423 Deutivacaftor [1] 299
6 CFTR [2] Tight junction, Vibrio cholerae infection D11507 Elexacaftor [1] 299
7 CFTR [2] Tight junction, Vibrio cholerae infection D11724 Galicaftor [1] 299
8 ERBB2 [1] Tight junction D04024 Lapatinib [3] 34, 74, 75
9 ERBB2 [1] Tight junction D08108 Lapatinib [3] 34, 74, 75
10 ERBB2 [1] Tight junction D11772 Tesevatinib [1] 67
11 MAP3K5 [2] Tight junction, TNF signaling pathway D10988 Selonsertib [1] 86
12 PRKAA1 [1] Tight junction D00944 Metformin [24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
13 PRKAA1 [1] Tight junction D04966 Metformin [24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
14 PRKAA2 [1] Tight junction D00944 Metformin [24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
15 PRKAA2 [1] Tight junction D04966 Metformin [24] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
16 PRKCE [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D09671 Sotrastaurin [1] 97
17 ROCK1 [3] Vascular smooth muscle contraction, Tight junction, Yersinia infection D07941 Fasudil [4] 2, 5, 7, 51
18 SRC [5] VEGF signaling pathway, Tight junction, Yersinia infection, Tuberculosis, Viral carcinogenesis D03252 Bosutinib [2] 2, 67
19 SRC [5] VEGF signaling pathway, Tight junction, Yersinia infection, Tuberculosis, Viral carcinogenesis D03658 Dasatinib [2] 51, 85
20 SRC [5] VEGF signaling pathway, Tight junction, Yersinia infection, Tuberculosis, Viral carcinogenesis D06414 Dasatinib [2] 51, 85
21 SRC [5] VEGF signaling pathway, Tight junction, Yersinia infection, Tuberculosis, Viral carcinogenesis D09664 Saracatinib [3] 6, 89, 272
22 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D00349 Isradipine [1] 6
23 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D00437 Nifedipine [2] 50, 81
24 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
25 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D00615 Amlodipine [4] 13, 51, 67, 298
26 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D00616 Diltiazem [3] 51, 58, 86
27 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D00617 Nicardipine [2] 70, 86
28 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D00619 Verapamil [3] 96, 140, 167
29 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D01173 Cilnidipine [1] 67
30 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D01908 Nilvadipine [1] 90
31 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D02356 Verapamil [3] 96, 140, 167
32 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D02914 Amlodipine [4] 13, 51, 67, 298
33 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D03830 Diltiazem [3] 51, 58, 86
34 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D05442 Perhexiline [2] 58, 272
35 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D07450 Amlodipine [4] 13, 51, 67, 298
36 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D07845 Diltiazem [3] 51, 58, 86
37 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D08270 Nicardipine [2] 70, 86
38 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D08340 Perhexiline [2] 58, 272
39 CACNA1D [3] Vascular smooth muscle contraction, Tight junction, Type II diabetes mellitus D08441 Propiverine [1] 226
40 ROCK2 [4] Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Yersinia infection D07941 Fasudil [4] 2, 5, 7, 51
41 ROCK2 [4] Vascular smooth muscle contraction, Wnt signaling pathway, Tight junction, Yersinia infection D11815 Belumosudil [1] 51