Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 ADA [1] Purine metabolism D11017 Elapegademase [1] 65
2 PDE10A [1] Purine metabolism D00227 Aminophylline [1] 63
3 PDE10A [1] Purine metabolism D00371 Theophylline [2] 236, 299
4 PDE10A [1] Purine metabolism D00718 Flavoxate [1] 226
5 PDE10A [1] Purine metabolism D01712 Theophylline [2] 236, 299
6 PDE10A [1] Purine metabolism D02017 Theophylline [2] 236, 299
7 PDE10A [1] Purine metabolism D05429 Aminophylline [1] 63
8 PDE10A [1] Purine metabolism D06103 Theophylline [2] 236, 299
9 PDE10A [1] Purine metabolism D06104 Theophylline [2] 236, 299
10 PDE10A [1] Purine metabolism D07546 Bucladesine [1] 246
11 PDE10A [1] Purine metabolism D07961 Flavoxate [1] 226
12 PDE7B [1] Purine metabolism D00227 Aminophylline [1] 63
13 PDE7B [1] Purine metabolism D00371 Theophylline [2] 236, 299
14 PDE7B [1] Purine metabolism D00718 Flavoxate [1] 226
15 PDE7B [1] Purine metabolism D01712 Theophylline [2] 236, 299
16 PDE7B [1] Purine metabolism D02017 Theophylline [2] 236, 299
17 PDE7B [1] Purine metabolism D05429 Aminophylline [1] 63
18 PDE7B [1] Purine metabolism D06103 Theophylline [2] 236, 299
19 PDE7B [1] Purine metabolism D06104 Theophylline [2] 236, 299
20 PDE7B [1] Purine metabolism D07546 Bucladesine [1] 246
21 PDE7B [1] Purine metabolism D07961 Flavoxate [1] 226
22 GUCY1A2 [4] Purine metabolism, Vascular smooth muscle contraction, Renin secretion, Salivary secretion D00517 Amyl Nitrite [1] 58
23 GUCY1A2 [4] Purine metabolism, Vascular smooth muscle contraction, Renin secretion, Salivary secretion D09572 Riociguat [6] 51, 84, 86, 88, 225, 299
24 GUCY1A1 [4] Purine metabolism, Vascular smooth muscle contraction, Renin secretion, Salivary secretion D00517 Amyl Nitrite [1] 58
25 GUCY1A1 [4] Purine metabolism, Vascular smooth muscle contraction, Renin secretion, Salivary secretion D09572 Riociguat [6] 51, 84, 86, 88, 225, 299
26 GUCY1B1 [4] Purine metabolism, Vascular smooth muscle contraction, Renin secretion, Salivary secretion D00517 Amyl Nitrite [1] 58
27 GUCY1B1 [4] Purine metabolism, Vascular smooth muscle contraction, Renin secretion, Salivary secretion D09572 Riociguat [6] 51, 84, 86, 88, 225, 299
28 GUCY2C [1] Purine metabolism D09355 Linaclotide [2] 6, 97
29 HPRT1 [1] Purine metabolism D00161 Mercaptopurine [4] 65, 96, 97, 164
30 HPRT1 [1] Purine metabolism D04931 Mercaptopurine [4] 65, 96, 97, 164
31 HPRT1 [1] Purine metabolism D06109 Tioguanine [2] 13, 37
32 HPRT1 [1] Purine metabolism D08603 Tioguanine [2] 13, 37
33 IMPDH1 [1] Purine metabolism D00752 Mycophenolate mofetil [34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
34 IMPDH1 [1] Purine metabolism D01392 Mizoribine [8] 46, 49, 51, 53, 66, 94, 222, 224
35 IMPDH1 [1] Purine metabolism D05094 Mycophenolate mofetil [34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
36 IMPDH1 [1] Purine metabolism D05095 Mycophenolate mofetil [34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
37 IMPDH1 [1] Purine metabolism D05096 Mycophenolic acid [36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
38 IMPDH2 [1] Purine metabolism D00752 Mycophenolate mofetil [34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
39 IMPDH2 [1] Purine metabolism D01392 Mizoribine [8] 46, 49, 51, 53, 66, 94, 222, 224
40 IMPDH2 [1] Purine metabolism D05094 Mycophenolate mofetil [34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
41 IMPDH2 [1] Purine metabolism D05095 Mycophenolate mofetil [34] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 85, 93, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300
42 IMPDH2 [1] Purine metabolism D05096 Mycophenolic acid [36] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 49, 51, 53, 60, 61, 62, 65, 66, 84, 85, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300
43 NPR1 [5] Purine metabolism, Vascular smooth muscle contraction, Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion D04051 Erythrityl tetranitrate [1] 46
44 NPR1 [5] Purine metabolism, Vascular smooth muscle contraction, Thermogenesis, Regulation of lipolysis in adipocytes, Renin secretion D05147 Nesiritide [2] 46, 58
45 NPR2 [2] Purine metabolism, Vascular smooth muscle contraction D04051 Erythrityl tetranitrate [1] 46
46 NPR2 [2] Purine metabolism, Vascular smooth muscle contraction D11190 Vosoritide [1] 276
47 PDE11A [1] Purine metabolism D00227 Aminophylline [1] 63
48 PDE11A [1] Purine metabolism D00371 Theophylline [2] 236, 299
49 PDE11A [1] Purine metabolism D00718 Flavoxate [1] 226
50 PDE11A [1] Purine metabolism D01712 Theophylline [2] 236, 299
51 PDE11A [1] Purine metabolism D02017 Theophylline [2] 236, 299
52 PDE11A [1] Purine metabolism D05429 Aminophylline [1] 63
53 PDE11A [1] Purine metabolism D06103 Theophylline [2] 236, 299
54 PDE11A [1] Purine metabolism D06104 Theophylline [2] 236, 299
55 PDE11A [1] Purine metabolism D07546 Bucladesine [1] 246
56 PDE11A [1] Purine metabolism D07961 Flavoxate [1] 226
57 PDE1A [3] Purine metabolism, Taste transduction, Renin secretion D00227 Aminophylline [1] 63
58 PDE1A [3] Purine metabolism, Taste transduction, Renin secretion D00371 Theophylline [2] 236, 299
59 PDE1A [3] Purine metabolism, Taste transduction, Renin secretion D00718 Flavoxate [1] 226
60 PDE1A [3] Purine metabolism, Taste transduction, Renin secretion D01712 Theophylline [2] 236, 299
61 PDE1A [3] Purine metabolism, Taste transduction, Renin secretion D02017 Theophylline [2] 236, 299
62 PDE1A [3] Purine metabolism, Taste transduction, Renin secretion D05429 Aminophylline [1] 63
63 PDE1A [3] Purine metabolism, Taste transduction, Renin secretion D06103 Theophylline [2] 236, 299
64 PDE1A [3] Purine metabolism, Taste transduction, Renin secretion D06104 Theophylline [2] 236, 299
65 PDE1A [3] Purine metabolism, Taste transduction, Renin secretion D07546 Bucladesine [1] 246
66 PDE1A [3] Purine metabolism, Taste transduction, Renin secretion D07961 Flavoxate [1] 226
67 PDE1C [3] Purine metabolism, Taste transduction, Renin secretion D00227 Aminophylline [1] 63
68 PDE1C [3] Purine metabolism, Taste transduction, Renin secretion D00371 Theophylline [2] 236, 299
69 PDE1C [3] Purine metabolism, Taste transduction, Renin secretion D00718 Flavoxate [1] 226
70 PDE1C [3] Purine metabolism, Taste transduction, Renin secretion D01712 Theophylline [2] 236, 299
71 PDE1C [3] Purine metabolism, Taste transduction, Renin secretion D02017 Theophylline [2] 236, 299
72 PDE1C [3] Purine metabolism, Taste transduction, Renin secretion D05429 Aminophylline [1] 63
73 PDE1C [3] Purine metabolism, Taste transduction, Renin secretion D06103 Theophylline [2] 236, 299
74 PDE1C [3] Purine metabolism, Taste transduction, Renin secretion D06104 Theophylline [2] 236, 299
75 PDE1C [3] Purine metabolism, Taste transduction, Renin secretion D07546 Bucladesine [1] 246
76 PDE1C [3] Purine metabolism, Taste transduction, Renin secretion D07961 Flavoxate [1] 226
77 PDE2A [1] Purine metabolism D00227 Aminophylline [1] 63
78 PDE2A [1] Purine metabolism D00371 Theophylline [2] 236, 299
79 PDE2A [1] Purine metabolism D00528 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
80 PDE2A [1] Purine metabolism D00718 Flavoxate [1] 226
81 PDE2A [1] Purine metabolism D01453 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
82 PDE2A [1] Purine metabolism D01712 Theophylline [2] 236, 299
83 PDE2A [1] Purine metabolism D02017 Theophylline [2] 236, 299
84 PDE2A [1] Purine metabolism D05429 Aminophylline [1] 63
85 PDE2A [1] Purine metabolism D06103 Theophylline [2] 236, 299
86 PDE2A [1] Purine metabolism D06104 Theophylline [2] 236, 299
87 PDE2A [1] Purine metabolism D07546 Bucladesine [1] 246
88 PDE2A [1] Purine metabolism D07961 Flavoxate [1] 226
89 PDE3A [2] Purine metabolism, Renin secretion D00227 Aminophylline [1] 63
90 PDE3A [2] Purine metabolism, Renin secretion D00371 Theophylline [2] 236, 299
91 PDE3A [2] Purine metabolism, Renin secretion D00417 Milrinone [1] 294
92 PDE3A [2] Purine metabolism, Renin secretion D00528 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
93 PDE3A [2] Purine metabolism, Renin secretion D00718 Flavoxate [1] 226
94 PDE3A [2] Purine metabolism, Renin secretion D01385 Ibudilast [2] 2, 13
95 PDE3A [2] Purine metabolism, Renin secretion D01453 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
96 PDE3A [2] Purine metabolism, Renin secretion D01712 Theophylline [2] 236, 299
97 PDE3A [2] Purine metabolism, Renin secretion D01896 Cilostazol [3] 51, 70, 124
98 PDE3A [2] Purine metabolism, Renin secretion D02017 Theophylline [2] 236, 299
99 PDE3A [2] Purine metabolism, Renin secretion D02085 Milrinone [1] 294
100 PDE3A [2] Purine metabolism, Renin secretion D04720 Levosimendan [1] 2
101 PDE3A [2] Purine metabolism, Renin secretion D05429 Aminophylline [1] 63
102 PDE3A [2] Purine metabolism, Renin secretion D06103 Theophylline [2] 236, 299
103 PDE3A [2] Purine metabolism, Renin secretion D06104 Theophylline [2] 236, 299
104 PDE3A [2] Purine metabolism, Renin secretion D07546 Bucladesine [1] 246
105 PDE3A [2] Purine metabolism, Renin secretion D07961 Flavoxate [1] 226
106 PDE3B [3] Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion D00227 Aminophylline [1] 63
107 PDE3B [3] Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion D00371 Theophylline [2] 236, 299
108 PDE3B [3] Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion D00417 Milrinone [1] 294
109 PDE3B [3] Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion D00528 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
110 PDE3B [3] Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion D00718 Flavoxate [1] 226
111 PDE3B [3] Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion D01385 Ibudilast [2] 2, 13
112 PDE3B [3] Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion D01453 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
113 PDE3B [3] Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion D01712 Theophylline [2] 236, 299
114 PDE3B [3] Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion D01896 Cilostazol [3] 51, 70, 124
115 PDE3B [3] Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion D02017 Theophylline [2] 236, 299
116 PDE3B [3] Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion D02085 Milrinone [1] 294
117 PDE3B [3] Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion D04720 Levosimendan [1] 2
118 PDE3B [3] Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion D05429 Aminophylline [1] 63
119 PDE3B [3] Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion D06103 Theophylline [2] 236, 299
120 PDE3B [3] Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion D06104 Theophylline [2] 236, 299
121 PDE3B [3] Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion D07546 Bucladesine [1] 246
122 PDE3B [3] Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion D07961 Flavoxate [1] 226
123 PDE4A [1] Purine metabolism D00227 Aminophylline [1] 63
124 PDE4A [1] Purine metabolism D00302 Dipyridamole [6] 46, 49, 51, 66, 96, 224
125 PDE4A [1] Purine metabolism D00371 Theophylline [2] 236, 299
126 PDE4A [1] Purine metabolism D00528 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
127 PDE4A [1] Purine metabolism D00718 Flavoxate [1] 226
128 PDE4A [1] Purine metabolism D01385 Ibudilast [2] 2, 13
129 PDE4A [1] Purine metabolism D01453 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
130 PDE4A [1] Purine metabolism D01712 Theophylline [2] 236, 299
131 PDE4A [1] Purine metabolism D01783 Rolipram [2] 8, 13
132 PDE4A [1] Purine metabolism D02017 Theophylline [2] 236, 299
133 PDE4A [1] Purine metabolism D05429 Aminophylline [1] 63
134 PDE4A [1] Purine metabolism D05744 Roflumilast [2] 84, 299
135 PDE4A [1] Purine metabolism D06103 Theophylline [2] 236, 299
136 PDE4A [1] Purine metabolism D06104 Theophylline [2] 236, 299
137 PDE4A [1] Purine metabolism D07546 Bucladesine [1] 246
138 PDE4A [1] Purine metabolism D07961 Flavoxate [1] 226
139 PDE4A [1] Purine metabolism D08860 Apremilast [7] 46, 50, 56, 97, 107, 162, 271
140 PDE4B [1] Purine metabolism D00227 Aminophylline [1] 63
141 PDE4B [1] Purine metabolism D00371 Theophylline [2] 236, 299
142 PDE4B [1] Purine metabolism D00528 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
143 PDE4B [1] Purine metabolism D00718 Flavoxate [1] 226
144 PDE4B [1] Purine metabolism D01385 Ibudilast [2] 2, 13
145 PDE4B [1] Purine metabolism D01453 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
146 PDE4B [1] Purine metabolism D01712 Theophylline [2] 236, 299
147 PDE4B [1] Purine metabolism D01783 Rolipram [2] 8, 13
148 PDE4B [1] Purine metabolism D02017 Theophylline [2] 236, 299
149 PDE4B [1] Purine metabolism D05429 Aminophylline [1] 63
150 PDE4B [1] Purine metabolism D05744 Roflumilast [2] 84, 299
151 PDE4B [1] Purine metabolism D06103 Theophylline [2] 236, 299
152 PDE4B [1] Purine metabolism D06104 Theophylline [2] 236, 299
153 PDE4B [1] Purine metabolism D07546 Bucladesine [1] 246
154 PDE4B [1] Purine metabolism D07961 Flavoxate [1] 226
155 PDE4B [1] Purine metabolism D08860 Apremilast [7] 46, 50, 56, 97, 107, 162, 271
156 PDE4C [1] Purine metabolism D00227 Aminophylline [1] 63
157 PDE4C [1] Purine metabolism D00371 Theophylline [2] 236, 299
158 PDE4C [1] Purine metabolism D00528 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
159 PDE4C [1] Purine metabolism D00718 Flavoxate [1] 226
160 PDE4C [1] Purine metabolism D01385 Ibudilast [2] 2, 13
161 PDE4C [1] Purine metabolism D01453 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
162 PDE4C [1] Purine metabolism D01712 Theophylline [2] 236, 299
163 PDE4C [1] Purine metabolism D01783 Rolipram [2] 8, 13
164 PDE4C [1] Purine metabolism D02017 Theophylline [2] 236, 299
165 PDE4C [1] Purine metabolism D05429 Aminophylline [1] 63
166 PDE4C [1] Purine metabolism D05744 Roflumilast [2] 84, 299
167 PDE4C [1] Purine metabolism D06103 Theophylline [2] 236, 299
168 PDE4C [1] Purine metabolism D06104 Theophylline [2] 236, 299
169 PDE4C [1] Purine metabolism D07546 Bucladesine [1] 246
170 PDE4C [1] Purine metabolism D07961 Flavoxate [1] 226
171 PDE4C [1] Purine metabolism D08860 Apremilast [7] 46, 50, 56, 97, 107, 162, 271
172 PDE4D [1] Purine metabolism D00227 Aminophylline [1] 63
173 PDE4D [1] Purine metabolism D00371 Theophylline [2] 236, 299
174 PDE4D [1] Purine metabolism D00528 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
175 PDE4D [1] Purine metabolism D00718 Flavoxate [1] 226
176 PDE4D [1] Purine metabolism D01385 Ibudilast [2] 2, 13
177 PDE4D [1] Purine metabolism D01453 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
178 PDE4D [1] Purine metabolism D01712 Theophylline [2] 236, 299
179 PDE4D [1] Purine metabolism D01783 Rolipram [2] 8, 13
180 PDE4D [1] Purine metabolism D02017 Theophylline [2] 236, 299
181 PDE4D [1] Purine metabolism D05429 Aminophylline [1] 63
182 PDE4D [1] Purine metabolism D05744 Roflumilast [2] 84, 299
183 PDE4D [1] Purine metabolism D06103 Theophylline [2] 236, 299
184 PDE4D [1] Purine metabolism D06104 Theophylline [2] 236, 299
185 PDE4D [1] Purine metabolism D07546 Bucladesine [1] 246
186 PDE4D [1] Purine metabolism D07961 Flavoxate [1] 226
187 PDE4D [1] Purine metabolism D08860 Apremilast [7] 46, 50, 56, 97, 107, 162, 271
188 PDE7A [1] Purine metabolism D00227 Aminophylline [1] 63
189 PDE7A [1] Purine metabolism D00371 Theophylline [2] 236, 299
190 PDE7A [1] Purine metabolism D00718 Flavoxate [1] 226
191 PDE7A [1] Purine metabolism D01712 Theophylline [2] 236, 299
192 PDE7A [1] Purine metabolism D02017 Theophylline [2] 236, 299
193 PDE7A [1] Purine metabolism D05429 Aminophylline [1] 63
194 PDE7A [1] Purine metabolism D06103 Theophylline [2] 236, 299
195 PDE7A [1] Purine metabolism D06104 Theophylline [2] 236, 299
196 PDE7A [1] Purine metabolism D07546 Bucladesine [1] 246
197 PDE7A [1] Purine metabolism D07961 Flavoxate [1] 226
198 PDE8A [1] Purine metabolism D00227 Aminophylline [1] 63
199 PDE8A [1] Purine metabolism D00371 Theophylline [2] 236, 299
200 PDE8A [1] Purine metabolism D00718 Flavoxate [1] 226
201 PDE8A [1] Purine metabolism D01712 Theophylline [2] 236, 299
202 PDE8A [1] Purine metabolism D02017 Theophylline [2] 236, 299
203 PDE8A [1] Purine metabolism D05429 Aminophylline [1] 63
204 PDE8A [1] Purine metabolism D06103 Theophylline [2] 236, 299
205 PDE8A [1] Purine metabolism D06104 Theophylline [2] 236, 299
206 PDE8A [1] Purine metabolism D07546 Bucladesine [1] 246
207 PDE8A [1] Purine metabolism D07961 Flavoxate [1] 226
208 PDE1B [3] Purine metabolism, Taste transduction, Renin secretion D00227 Aminophylline [1] 63
209 PDE1B [3] Purine metabolism, Taste transduction, Renin secretion D00371 Theophylline [2] 236, 299
210 PDE1B [3] Purine metabolism, Taste transduction, Renin secretion D00528 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
211 PDE1B [3] Purine metabolism, Taste transduction, Renin secretion D00718 Flavoxate [1] 226
212 PDE1B [3] Purine metabolism, Taste transduction, Renin secretion D01453 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
213 PDE1B [3] Purine metabolism, Taste transduction, Renin secretion D01712 Theophylline [2] 236, 299
214 PDE1B [3] Purine metabolism, Taste transduction, Renin secretion D02017 Theophylline [2] 236, 299
215 PDE1B [3] Purine metabolism, Taste transduction, Renin secretion D05429 Aminophylline [1] 63
216 PDE1B [3] Purine metabolism, Taste transduction, Renin secretion D06103 Theophylline [2] 236, 299
217 PDE1B [3] Purine metabolism, Taste transduction, Renin secretion D06104 Theophylline [2] 236, 299
218 PDE1B [3] Purine metabolism, Taste transduction, Renin secretion D07546 Bucladesine [1] 246
219 PDE1B [3] Purine metabolism, Taste transduction, Renin secretion D07961 Flavoxate [1] 226
220 RRM1 [2] Purine metabolism, Pyrimidine metabolism D01370 Cladribine [3] 11, 13, 94
221 RRM1 [2] Purine metabolism, Pyrimidine metabolism D01907 Fludarabine [19] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326
222 RRM1 [2] Purine metabolism, Pyrimidine metabolism D03546 Clofarabine [9] 19, 20, 40, 46, 49, 60, 96, 234, 326
223 RRM1 [2] Purine metabolism, Pyrimidine metabolism D07966 Fludarabine [19] 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 286, 326
224 RRM2 [2] Purine metabolism, Pyrimidine metabolism D00341 Hydroxyurea [8] 3, 13, 19, 20, 65, 85, 86, 284
225 XDH [1] Purine metabolism D00224 Allopurinol [6] 6, 46, 57, 66, 96, 97
226 XDH [1] Purine metabolism D01206 Febuxostat [3] 2, 6, 13
227 PDE8B [1] Purine metabolism D00227 Aminophylline [1] 63
228 PDE8B [1] Purine metabolism D00371 Theophylline [2] 236, 299
229 PDE8B [1] Purine metabolism D00718 Flavoxate [1] 226
230 PDE8B [1] Purine metabolism D01712 Theophylline [2] 236, 299
231 PDE8B [1] Purine metabolism D02017 Theophylline [2] 236, 299
232 PDE8B [1] Purine metabolism D05429 Aminophylline [1] 63
233 PDE8B [1] Purine metabolism D06103 Theophylline [2] 236, 299
234 PDE8B [1] Purine metabolism D06104 Theophylline [2] 236, 299
235 PDE8B [1] Purine metabolism D07546 Bucladesine [1] 246
236 PDE8B [1] Purine metabolism D07961 Flavoxate [1] 226
237 PDE5A [1] Purine metabolism D00302 Dipyridamole [6] 46, 49, 51, 66, 96, 224
238 PDE5A [1] Purine metabolism D00528 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
239 PDE5A [1] Purine metabolism D01453 Caffeine [9] 2, 6, 13, 21, 46, 78, 96, 97, 265
240 PDE5A [1] Purine metabolism D02008 Tadalafil [7] 6, 51, 75, 84, 86, 113, 210
241 PDE5A [1] Purine metabolism D02229 Sildenafil [17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
242 PDE5A [1] Purine metabolism D02731 Vardenafil [3] 13, 86, 299
243 PDE5A [1] Purine metabolism D03260 Vardenafil [3] 13, 86, 299
244 PDE5A [1] Purine metabolism D08514 Sildenafil [17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
245 PDE5A [1] Purine metabolism D08668 Vardenafil [3] 13, 86, 299
246 PDE5A [1] Purine metabolism D10027 Udenafil [2] 86, 210