Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 MAPK14 [12] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
2 MAPK14 [12] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
3 FGFR1 [2] Signaling pathways regulating pluripotency of stem cells, Thermogenesis D10481 Nintedanib [5] 51, 85, 89, 227, 228
4 FGFR1 [2] Signaling pathways regulating pluripotency of stem cells, Thermogenesis D11589 Infigratinib [1] 276
5 FGFR3 [1] Signaling pathways regulating pluripotency of stem cells D10481 Nintedanib [5] 51, 85, 89, 227, 228
6 FGFR3 [1] Signaling pathways regulating pluripotency of stem cells D11589 Infigratinib [1] 276
7 FGFR2 [1] Signaling pathways regulating pluripotency of stem cells D05338 Palifermin [5] 13, 36, 38, 39, 65
8 FGFR2 [1] Signaling pathways regulating pluripotency of stem cells D10481 Nintedanib [5] 51, 85, 89, 227, 228
9 FGFR2 [1] Signaling pathways regulating pluripotency of stem cells D11589 Infigratinib [1] 276
10 IGF1R [2] Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer D03297 Mecasermin [6] 65, 78, 96, 168, 265, 299
11 IGF1R [2] Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer D04870 Mecasermin [6] 65, 78, 96, 168, 265, 299
12 IGF1R [2] Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer D09680 Teprotumumab [1] 51
13 IGF1R [2] Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer D09925 Linsitinib [1] 232
14 JAK1 [6] Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis D09959 Ruxolitinib [1] 228
15 JAK1 [6] Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis D09970 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
16 JAK1 [6] Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis D10308 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325
17 JAK1 [6] Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis D10653 Peficitinib [1] 46
18 JAK1 [6] Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis D10871 Filgotinib [6] 46, 53, 96, 97, 222, 271
19 JAK1 [6] Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis D10944 Itacitinib [5] 46, 51, 60, 97, 228
20 JAK1 [6] Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis D10994 Upadacitinib [8] 40, 41, 46, 49, 96, 97, 107, 271
21 JAK2 [5] Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis D09959 Ruxolitinib [1] 228
22 JAK2 [5] Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis D09970 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
23 JAK2 [5] Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis D10308 Baricitinib [13] 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 268, 269, 325
24 JAK2 [5] Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis D10653 Peficitinib [1] 46
25 JAK3 [4] Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral carcinogenesis D09970 Tofacitinib [15] 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 256, 271
26 JAK3 [4] Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral carcinogenesis D10653 Peficitinib [1] 46
27 PIK3CA [12] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis, Small cell lung cancer D11158 Leniolisib [2] 53, 65
28 PIK3CB [12] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis, Small cell lung cancer D11158 Leniolisib [2] 53, 65
29 PIK3CD [12] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis, Small cell lung cancer D11158 Leniolisib [2] 53, 65
30 PIK3CD [12] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Spinocerebellar ataxia, Yersinia infection, Viral carcinogenesis, Small cell lung cancer D11437 Parsaclisib [3] 35, 53, 61
31 MAPK11 [12] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
32 MAPK11 [12] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
33 MAPK13 [12] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
34 MAPK13 [12] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
35 MAP2K1 [10] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Yersinia infection, Thyroid cancer D09666 Selumetinib [1] 34
36 MAP2K1 [10] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Yersinia infection, Thyroid cancer D10175 Trametinib [4] 2, 34, 279, 280
37 MAP2K1 [10] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Yersinia infection, Thyroid cancer D10405 Cobimetinib [1] 280
38 MAP2K1 [10] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Yersinia infection, Thyroid cancer D10604 Binimetinib [1] 34
39 MAP2K2 [9] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Thyroid hormone signaling pathway, Yersinia infection, Thyroid cancer D09666 Selumetinib [1] 34
40 MAP2K2 [9] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Thyroid hormone signaling pathway, Yersinia infection, Thyroid cancer D10175 Trametinib [4] 2, 34, 279, 280
41 MAP2K2 [9] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Thyroid hormone signaling pathway, Yersinia infection, Thyroid cancer D10405 Cobimetinib [1] 280
42 MAP2K2 [9] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, T cell receptor signaling pathway, Thyroid hormone signaling pathway, Yersinia infection, Thyroid cancer D10604 Binimetinib [1] 34
43 RAF1 [7] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Thyroid hormone signaling pathway, Tuberculosis D06272 Sorafenib [2] 34, 86
44 RAF1 [7] Sphingolipid signaling pathway, Vascular smooth muscle contraction, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, T cell receptor signaling pathway, Thyroid hormone signaling pathway, Tuberculosis D08524 Sorafenib [2] 34, 86
45 MAPK12 [12] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D09639 Losmapimod [2] 113, 222
46 MAPK12 [12] Sphingolipid signaling pathway, VEGF signaling pathway, Signaling pathways regulating pluripotency of stem cells, Toll-like receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, Thermogenesis, Yersinia infection, Toxoplasmosis, Tuberculosis D10959 Neflamapimod [1] 8
47 BMPR2 [2] TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells D03779 Dibotermin alfa [1] 34
48 ACVR2A [2] TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells D09670 Sotatercept [2] 86, 284
49 ACVR2A [2] TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells D10620 Bimagrumab [1] 15
50 ACVR2B [2] TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells D10620 Bimagrumab [1] 15