Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 SLC6A1 [1] Synaptic vesicle cycle D00332 Gabapentin [5] 6, 13, 19, 70, 298
2 SLC6A2 [1] Synaptic vesicle cycle D00228 Amoxapine [1] 46
3 SLC6A2 [1] Synaptic vesicle cycle D00809 Amitriptyline [4] 78, 97, 226, 299
4 SLC6A2 [1] Synaptic vesicle cycle D00812 Desipramine [2] 120, 156
5 SLC6A2 [1] Synaptic vesicle cycle D00814 Doxepin [1] 6
6 SLC6A2 [1] Synaptic vesicle cycle D00816 Nortriptyline [2] 6, 226
7 SLC6A2 [1] Synaptic vesicle cycle D00817 Bupropion [5] 8, 18, 21, 96, 171
8 SLC6A2 [1] Synaptic vesicle cycle D00821 Venlafaxine [3] 6, 13, 46
9 SLC6A2 [1] Synaptic vesicle cycle D01179 Duloxetine [2] 6, 13
10 SLC6A2 [1] Synaptic vesicle cycle D01296 Methylphenidate [7] 6, 13, 34, 84, 113, 179, 206
11 SLC6A2 [1] Synaptic vesicle cycle D02574 Atomoxetine [4] 6, 8, 13, 17
12 SLC6A2 [1] Synaptic vesicle cycle D04999 Methylphenidate [7] 6, 13, 34, 84, 113, 179, 206
13 SLC6A2 [1] Synaptic vesicle cycle D05458 Phentermine [1] 97
14 SLC6A2 [1] Synaptic vesicle cycle D05459 Phentermine [1] 97
15 SLC6A2 [1] Synaptic vesicle cycle D07448 Amitriptyline [4] 78, 97, 226, 299
16 SLC6A2 [1] Synaptic vesicle cycle D07473 Atomoxetine [4] 6, 8, 13, 17
17 SLC6A2 [1] Synaptic vesicle cycle D07591 Bupropion [5] 8, 18, 21, 96, 171
18 SLC6A2 [1] Synaptic vesicle cycle D07791 Desipramine [2] 120, 156
19 SLC6A2 [1] Synaptic vesicle cycle D07875 Doxepin [1] 6
20 SLC6A2 [1] Synaptic vesicle cycle D07880 Duloxetine [2] 6, 13
21 SLC6A2 [1] Synaptic vesicle cycle D07938 Bupropion [5] 8, 18, 21, 96, 171
22 SLC6A2 [1] Synaptic vesicle cycle D08130 Lisdexamfetamine [1] 13
23 SLC6A2 [1] Synaptic vesicle cycle D08222 Milnacipran [2] 46, 49
24 SLC6A2 [1] Synaptic vesicle cycle D08288 Nortriptyline [2] 6, 226
25 SLC6A2 [1] Synaptic vesicle cycle D08670 Venlafaxine [3] 6, 13, 46
26 SLC6A2 [1] Synaptic vesicle cycle D11688 Ampreloxetine [2] 6, 17
27 SLC6A3 [1] Synaptic vesicle cycle D00817 Bupropion [5] 8, 18, 21, 96, 171
28 SLC6A3 [1] Synaptic vesicle cycle D01296 Methylphenidate [7] 6, 13, 34, 84, 113, 179, 206
29 SLC6A3 [1] Synaptic vesicle cycle D03215 Armodafinil [3] 6, 13, 84
30 SLC6A3 [1] Synaptic vesicle cycle D04999 Methylphenidate [7] 6, 13, 34, 84, 113, 179, 206
31 SLC6A3 [1] Synaptic vesicle cycle D05458 Phentermine [1] 97
32 SLC6A3 [1] Synaptic vesicle cycle D05459 Phentermine [1] 97
33 SLC6A3 [1] Synaptic vesicle cycle D07591 Bupropion [5] 8, 18, 21, 96, 171
34 SLC6A3 [1] Synaptic vesicle cycle D07938 Bupropion [5] 8, 18, 21, 96, 171
35 SLC6A3 [1] Synaptic vesicle cycle D08130 Lisdexamfetamine [1] 13
36 SLC6A4 [1] Synaptic vesicle cycle D00228 Amoxapine [1] 46
37 SLC6A4 [1] Synaptic vesicle cycle D00326 Fluoxetine [6] 13, 17, 78, 86, 179, 206
38 SLC6A4 [1] Synaptic vesicle cycle D00809 Amitriptyline [4] 78, 97, 226, 299
39 SLC6A4 [1] Synaptic vesicle cycle D00812 Desipramine [2] 120, 156
40 SLC6A4 [1] Synaptic vesicle cycle D00814 Doxepin [1] 6
41 SLC6A4 [1] Synaptic vesicle cycle D00816 Nortriptyline [2] 6, 226
42 SLC6A4 [1] Synaptic vesicle cycle D00820 Trazodone [1] 2
43 SLC6A4 [1] Synaptic vesicle cycle D00821 Venlafaxine [3] 6, 13, 46
44 SLC6A4 [1] Synaptic vesicle cycle D00822 Citalopram [7] 6, 8, 13, 18, 46, 98, 127
45 SLC6A4 [1] Synaptic vesicle cycle D00823 Fluoxetine [6] 13, 17, 78, 86, 179, 206
46 SLC6A4 [1] Synaptic vesicle cycle D00825 Sertraline [2] 6, 206
47 SLC6A4 [1] Synaptic vesicle cycle D01179 Duloxetine [2] 6, 13
48 SLC6A4 [1] Synaptic vesicle cycle D02260 Paroxetine [4] 6, 13, 46, 85
49 SLC6A4 [1] Synaptic vesicle cycle D02360 Sertraline [2] 6, 206
50 SLC6A4 [1] Synaptic vesicle cycle D02362 Paroxetine [4] 6, 13, 46, 85
51 SLC6A4 [1] Synaptic vesicle cycle D02567 Escitalopram [3] 2, 6, 13
52 SLC6A4 [1] Synaptic vesicle cycle D05374 Paroxetine [4] 6, 13, 46, 85
53 SLC6A4 [1] Synaptic vesicle cycle D05375 Paroxetine [4] 6, 13, 46, 85
54 SLC6A4 [1] Synaptic vesicle cycle D05458 Phentermine [1] 97
55 SLC6A4 [1] Synaptic vesicle cycle D05459 Phentermine [1] 97
56 SLC6A4 [1] Synaptic vesicle cycle D07448 Amitriptyline [4] 78, 97, 226, 299
57 SLC6A4 [1] Synaptic vesicle cycle D07704 Citalopram [7] 6, 8, 13, 18, 46, 98, 127
58 SLC6A4 [1] Synaptic vesicle cycle D07704 Escitalopram [3] 2, 6, 13
59 SLC6A4 [1] Synaptic vesicle cycle D07791 Desipramine [2] 120, 156
60 SLC6A4 [1] Synaptic vesicle cycle D07875 Doxepin [1] 6
61 SLC6A4 [1] Synaptic vesicle cycle D07880 Duloxetine [2] 6, 13
62 SLC6A4 [1] Synaptic vesicle cycle D07913 Escitalopram [3] 2, 6, 13
63 SLC6A4 [1] Synaptic vesicle cycle D07945 Fenfluramine [4] 140, 144, 145, 149
64 SLC6A4 [1] Synaptic vesicle cycle D08222 Milnacipran [2] 46, 49
65 SLC6A4 [1] Synaptic vesicle cycle D08288 Nortriptyline [2] 6, 226
66 SLC6A4 [1] Synaptic vesicle cycle D08626 Trazodone [1] 2
67 SLC6A4 [1] Synaptic vesicle cycle D08670 Venlafaxine [3] 6, 13, 46
68 SLC6A4 [1] Synaptic vesicle cycle D10184 Vortioxetine [1] 6
69 SLC6A4 [1] Synaptic vesicle cycle D11688 Ampreloxetine [2] 6, 17
70 SLC18A2 [1] Synaptic vesicle cycle D08575 Tetrabenazine [1] 8
71 SLC18A2 [1] Synaptic vesicle cycle D10675 Valbenazine [1] 8
72 SLC18A2 [1] Synaptic vesicle cycle D10701 Deutetrabenazine [1] 8
73 SNAP25 [1] Synaptic vesicle cycle D00783 Botulinum toxin type A [13] 2, 5, 6, 7, 13, 15, 17, 36, 51, 70, 113, 149, 226
74 SNAP25 [1] Synaptic vesicle cycle D02735 Botulinum toxin type B [4] 2, 6, 13, 51
75 CACNA1B [2] Synaptic vesicle cycle, Type II diabetes mellitus D01173 Cilnidipine [1] 67