Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 MTOR [1] Type II diabetes mellitus D00753 Sirolimus [41] 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
2 MTOR [1] Type II diabetes mellitus D02714 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277
3 MTOR [1] Type II diabetes mellitus D06068 Temsirolimus [4] 13, 34, 89, 331
4 INSR [1] Type II diabetes mellitus D00085 Insulin human [2] 96, 156
5 INSR [1] Type II diabetes mellitus D03230 Insulin human [2] 96, 156
6 INSR [1] Type II diabetes mellitus D03250 Insulin glargine [1] 299
7 INSR [1] Type II diabetes mellitus D04539 Insulin detemir [1] 299
8 KCNJ11 [1] Type II diabetes mellitus D00294 Diazoxide [2] 13, 193
9 KCNJ11 [1] Type II diabetes mellitus D00418 Minoxidil [1] 179
10 KCNJ11 [1] Type II diabetes mellitus D00594 Repaglinide [3] 6, 21, 299
11 KCNJ11 [1] Type II diabetes mellitus D00636 Amiodarone [2] 28, 127
12 KCNJ11 [1] Type II diabetes mellitus D02910 Amiodarone [2] 28, 127
13 PIK3CA [4] VEGF signaling pathway, Type II diabetes mellitus, Yersinia infection, Viral carcinogenesis D11158 Leniolisib [2] 53, 65
14 PIK3CB [4] VEGF signaling pathway, Type II diabetes mellitus, Yersinia infection, Viral carcinogenesis D11158 Leniolisib [2] 53, 65
15 PIK3CD [4] VEGF signaling pathway, Type II diabetes mellitus, Yersinia infection, Viral carcinogenesis D11158 Leniolisib [2] 53, 65
16 PIK3CD [4] VEGF signaling pathway, Type II diabetes mellitus, Yersinia infection, Viral carcinogenesis D11437 Parsaclisib [3] 35, 53, 61
17 PRKCD [2] Vascular smooth muscle contraction, Type II diabetes mellitus D09671 Sotrastaurin [1] 97
18 PRKCE [2] Vascular smooth muscle contraction, Type II diabetes mellitus D09671 Sotrastaurin [1] 97
19 ABCC8 [1] Type II diabetes mellitus D00294 Diazoxide [2] 13, 193
20 ABCC8 [1] Type II diabetes mellitus D00418 Minoxidil [1] 179
21 ABCC8 [1] Type II diabetes mellitus D00594 Repaglinide [3] 6, 21, 299
22 TNF [3] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Yersinia infection D00742 Etanercept [17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
23 TNF [3] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Yersinia infection D00754 Thalidomide [20] 2, 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331
24 TNF [3] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Yersinia infection D01583 Pirfenidone [11] 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228
25 TNF [3] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Yersinia infection D02597 Adalimumab [18] 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 151, 160, 164, 222, 226, 269, 270, 271
26 TNF [3] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Yersinia infection D02598 Infliximab [27] 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
27 TNF [3] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Yersinia infection D03441 Certolizumab pegol [8] 37, 46, 49, 96, 97, 107, 226, 271
28 TNF [3] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Yersinia infection D04358 Golimumab [8] 46, 56, 84, 96, 97, 107, 270, 271
29 TNF [3] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Yersinia infection D04687 Lenalidomide [8] 16, 26, 28, 34, 49, 284, 300, 331
30 TNF [3] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Yersinia infection D05393 Pegsunercept [1] 46
31 TNF [3] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Yersinia infection D08976 Pomalidomide [6] 28, 34, 51, 85, 227, 331
32 TNF [3] Viral protein interaction with cytokine and cytokine receptor, Type II diabetes mellitus, Yersinia infection D09944 Ozoralizumab [1] 46
33 CACNA1B [1] Type II diabetes mellitus D01173 Cilnidipine [1] 67
34 CACNA1C [2] Vascular smooth muscle contraction, Type II diabetes mellitus D00349 Isradipine [1] 6
35 CACNA1C [2] Vascular smooth muscle contraction, Type II diabetes mellitus D00437 Nifedipine [2] 50, 81
36 CACNA1C [2] Vascular smooth muscle contraction, Type II diabetes mellitus D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
37 CACNA1C [2] Vascular smooth muscle contraction, Type II diabetes mellitus D00615 Amlodipine [4] 13, 51, 67, 298
38 CACNA1C [2] Vascular smooth muscle contraction, Type II diabetes mellitus D00616 Diltiazem [3] 51, 58, 86
39 CACNA1C [2] Vascular smooth muscle contraction, Type II diabetes mellitus D00617 Nicardipine [2] 70, 86
40 CACNA1C [2] Vascular smooth muscle contraction, Type II diabetes mellitus D00619 Verapamil [3] 96, 140, 167
41 CACNA1C [2] Vascular smooth muscle contraction, Type II diabetes mellitus D01173 Cilnidipine [1] 67
42 CACNA1C [2] Vascular smooth muscle contraction, Type II diabetes mellitus D01908 Nilvadipine [1] 90
43 CACNA1C [2] Vascular smooth muscle contraction, Type II diabetes mellitus D02356 Verapamil [3] 96, 140, 167
44 CACNA1C [2] Vascular smooth muscle contraction, Type II diabetes mellitus D02914 Amlodipine [4] 13, 51, 67, 298
45 CACNA1C [2] Vascular smooth muscle contraction, Type II diabetes mellitus D03830 Diltiazem [3] 51, 58, 86
46 CACNA1C [2] Vascular smooth muscle contraction, Type II diabetes mellitus D05442 Perhexiline [2] 58, 272
47 CACNA1C [2] Vascular smooth muscle contraction, Type II diabetes mellitus D07450 Amlodipine [4] 13, 51, 67, 298
48 CACNA1C [2] Vascular smooth muscle contraction, Type II diabetes mellitus D07845 Diltiazem [3] 51, 58, 86
49 CACNA1C [2] Vascular smooth muscle contraction, Type II diabetes mellitus D08270 Nicardipine [2] 70, 86
50 CACNA1C [2] Vascular smooth muscle contraction, Type II diabetes mellitus D08340 Perhexiline [2] 58, 272
51 CACNA1C [2] Vascular smooth muscle contraction, Type II diabetes mellitus D08441 Propiverine [1] 226
52 CACNA1D [2] Vascular smooth muscle contraction, Type II diabetes mellitus D00349 Isradipine [1] 6
53 CACNA1D [2] Vascular smooth muscle contraction, Type II diabetes mellitus D00437 Nifedipine [2] 50, 81
54 CACNA1D [2] Vascular smooth muscle contraction, Type II diabetes mellitus D00537 Topiramate [6] 6, 97, 140, 144, 156, 193
55 CACNA1D [2] Vascular smooth muscle contraction, Type II diabetes mellitus D00615 Amlodipine [4] 13, 51, 67, 298
56 CACNA1D [2] Vascular smooth muscle contraction, Type II diabetes mellitus D00616 Diltiazem [3] 51, 58, 86
57 CACNA1D [2] Vascular smooth muscle contraction, Type II diabetes mellitus D00617 Nicardipine [2] 70, 86
58 CACNA1D [2] Vascular smooth muscle contraction, Type II diabetes mellitus D00619 Verapamil [3] 96, 140, 167
59 CACNA1D [2] Vascular smooth muscle contraction, Type II diabetes mellitus D01173 Cilnidipine [1] 67
60 CACNA1D [2] Vascular smooth muscle contraction, Type II diabetes mellitus D01908 Nilvadipine [1] 90
61 CACNA1D [2] Vascular smooth muscle contraction, Type II diabetes mellitus D02356 Verapamil [3] 96, 140, 167
62 CACNA1D [2] Vascular smooth muscle contraction, Type II diabetes mellitus D02914 Amlodipine [4] 13, 51, 67, 298
63 CACNA1D [2] Vascular smooth muscle contraction, Type II diabetes mellitus D03830 Diltiazem [3] 51, 58, 86
64 CACNA1D [2] Vascular smooth muscle contraction, Type II diabetes mellitus D05442 Perhexiline [2] 58, 272
65 CACNA1D [2] Vascular smooth muscle contraction, Type II diabetes mellitus D07450 Amlodipine [4] 13, 51, 67, 298
66 CACNA1D [2] Vascular smooth muscle contraction, Type II diabetes mellitus D07845 Diltiazem [3] 51, 58, 86
67 CACNA1D [2] Vascular smooth muscle contraction, Type II diabetes mellitus D08270 Nicardipine [2] 70, 86
68 CACNA1D [2] Vascular smooth muscle contraction, Type II diabetes mellitus D08340 Perhexiline [2] 58, 272
69 CACNA1D [2] Vascular smooth muscle contraction, Type II diabetes mellitus D08441 Propiverine [1] 226
70 CACNA1G [1] Type II diabetes mellitus D00399 Valproic acid [17] 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
71 CACNA1G [1] Type II diabetes mellitus D00538 Zonisamide [1] 6
72 CACNA1G [1] Type II diabetes mellitus D01303 Flunarizine [4] 58, 86, 149, 215
73 CACNA1G [1] Type II diabetes mellitus D07971 Flunarizine [4] 58, 86, 149, 215