| 1 | Alkaline Phosphatase | [1]  Alkaline Phosphatase Alkaline Phosphatase | - | - | - | [4]  46 46, 93, 97, 172 💬
 | 
| 2 | ALXN1850 | - | - | - | - | [1]  172 172 💬
 | 
| 3 | Asfotas Alfa | - | - | - | - | [1]  172 172 💬
 | 
| 4 | ASFOTASE ALFA | [1]  Asfotase alfa Asfotase alfa | [1]  Asfotase alfa 
                
                    Asfotase alfa
                
             💬
 | [1]  ALPL ALPL 💬
 | [4]  Biosynthesis of cofactors Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, Thiamine metabolism 💬 | [1]  172 172 💬
 | 
| 5 | Asfotase Alfa (ALXN1215) | [1]  Asfotase alfa Asfotase alfa | [1]  Asfotase alfa 
                
                    Asfotase alfa
                
             💬
 | [1]  ALPL ALPL 💬
 | [4]  Biosynthesis of cofactors Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, Thiamine metabolism 💬 | [1]  172 172 💬
 | 
| 6 | BPS804 | - | - | - | - | [2]  172 172, 274 💬
 | 
| 7 | Cyclophosphamide | [1]  Cyclophosphamide Cyclophosphamide | [2]  Cyclophosphamide 
                
                    Cyclophosphamide
                
            , 
                
                    Cyclophosphamide
                
             💬
 | - | - | [44]  11 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331 💬
 | 
| 8 | ENB-0040 | - | - | - | - | [1]  172 172 💬
 | 
| 9 | Fully human IgG2 lambda monoclonal antibody | - | - | - | - | [1]  172 172 💬
 | 
| 10 | Human Recombinant Tissue Non-Specific Alkaline Phosphatase Fusion Protein | [1]  Alkaline Phosphatase Alkaline Phosphatase | - | - | - | [1]  172 172 💬
 | 
| 11 | Methotrexate | [1]  Methotrexate Methotrexate | [1]  Methotrexate 
                
                    Methotrexate
                
             💬
 | [2]  DHFR DHFR, DHFR2 💬
 | [5]  Antifolate resistance Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬 | [38]  11 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 283, 284, 285, 286, 326, 331 💬
 | 
| 12 | Retrospective Case Only | - | - | - | - | [1]  172 172 💬
 | 
| 13 | Strensiq | [1]  Asfotase alfa Asfotase alfa | [1]  Asfotase alfa 
                
                    Asfotase alfa
                
             💬
 | [1]  ALPL ALPL 💬
 | [4]  Biosynthesis of cofactors Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, Thiamine metabolism 💬 | [1]  172 172 💬
 | 
| 14 | Whole genome sequencing | - | - | - | - | [3]  6 6, 79, 172 💬
 |