Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Acetate[1] Acetate---[41] 1, 2, 6, 10, 13, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 171, 206, 222, 224, 225, 227, 235, 251, 265, 288, 298, 299 💬
2Acetazolamide[1] Acetazolamide[1] Acetazolamide 💬 [13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬 		[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[6] 13, 90, 115, 155, 225, 230 💬
3Acetazolamide Sandoz 250[1] Acetazolamide[1] Acetazolamide 💬 [13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬 		[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[1] 225 💬
4Adempas[1] Riociguat[1] Riociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[5] 51, 86, 88, 225, 299 💬
5Amiloride[1] Amiloride[1] Amiloride 💬 [3] SCNN1A,
SCNN1B,
SCNN1G 💬 		[2] Aldosterone-regulated sodium reabsorption, Taste transduction 💬[4] 13, 67, 225, 299 💬
6Anhydrous Amiloride Hydrochloride[1] Amiloride[1] Amiloride 💬 [3] SCNN1A,
SCNN1B,
SCNN1G 💬 		[2] Aldosterone-regulated sodium reabsorption, Taste transduction 💬[1] 225 💬
7Atorvastatin[1] Atorvastatin[1] Atorvastatin 💬 [1] HMGCR 💬 [4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
8Calcitonin----[1] 225 💬
9CALCITONIN (SALMON)[1] Salmon, unspecified---[1] 225 💬
10Chlorothiazide[1] Chlorothiazide[1] Chlorothiazide 💬 [1] SLC12A3 💬 -[1] 225 💬
11Confortid----[1] 225 💬
12Desmopressin[1] Desmopressin[1] Desmopressin 💬 [2] AVPR2,
F8 💬 		[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[5] 6, 64, 72, 225, 288 💬
13DESMOPRESSIN ACETATE TRIHYDRATE[2] Acetate,
Desmopressin		[1] Desmopressin 💬 [2] AVPR2,
F8 💬 		[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 225 💬
14Desmopressine[1] Desmopressin[1] Desmopressin 💬 [2] AVPR2,
F8 💬 		[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[2] 225, 288 💬
15Desmopressine nasal spray 10 mg/ml, flacon 60 doses[1] Desmopressin[1] Desmopressin 💬 [2] AVPR2,
F8 💬 		[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[1] 225 💬
16Esidrix[1] Hydrochlorothiazide[1] Hydrochlorothiazide 💬 [1] SLC12A3 💬 -[1] 225 💬
17FLUCONAZOLE[1] Fluconazole[1] Fluconazole 💬 --[2] 96, 225 💬
18Hydrochloorthiazide----[1] 225 💬
19HYDROCHLOROTHIAZIDE[1] Hydrochlorothiazide[1] Hydrochlorothiazide 💬 [1] SLC12A3 💬 -[4] 13, 67, 225, 235 💬
20Hydrochlorothiazide/amiloride[2] Amiloride,
Hydrochlorothiazide		[2] Hydrochlorothiazide ,
Amiloride 💬 		[4] SCNN1A,
SCNN1B,
SCNN1G,
SLC12A3 💬 		[2] Aldosterone-regulated sodium reabsorption, Taste transduction 💬[1] 225 💬
21INDOMETACIN[1] Indomethacin[1] Indomethacin 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 225 💬
22Indomethacin[1] Indomethacin[1] Indomethacin 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 225, 271, 298 💬
23Losec[1] Omeprazole[1] Omeprazole 💬 [2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[3] 46, 225, 294 💬
24Magnesium[1] Magnesium---[15] 6, 11, 46, 64, 70, 93, 97, 166, 225, 235, 284, 291, 296, 297, 298 💬
25Metformin[1] Metformin[1] Metformin 💬 [2] PRKAA1,
PRKAA2 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[25] 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
26Miacalcic----[1] 225 💬
27Midamor[1] Amiloride[1] Amiloride 💬 [3] SCNN1A,
SCNN1B,
SCNN1G 💬 		[2] Aldosterone-regulated sodium reabsorption, Taste transduction 💬[1] 225 💬
28Omeprazole[1] Omeprazole[1] Omeprazole 💬 [2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
29OMEPRAZOLE MAGNESIUM[2] Magnesium,
Omeprazole		[1] Omeprazole 💬 [2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[1] 225 💬
30PB----[2] 67, 225 💬
31RIOCIGUAT[1] Riociguat[1] Riociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[6] 51, 84, 86, 88, 225, 299 💬
32Salmon[1] Salmon, unspecified---[3] 96, 97, 225 💬
33Sevoflurane[1] Sevoflurane[1] Sevoflurane 💬 --[7] 6, 21, 22, 34, 98, 225, 296 💬
34Sildenafil[1] Sildenafil[1] Sildenafil 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
35Sildenafil citrate[1] Sildenafil[1] Sildenafil 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[4] 51, 85, 86, 225 💬
36Spirix----[1] 225 💬
37Spironolactone[1] Spironolactone[1] Spironolactone 💬 [1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption 💬[8] 46, 58, 67, 86, 113, 210, 218, 225 💬
38SUB21605----[1] 225 💬
39TOLVAPTAN[1] Tolvaptan[1] Tolvaptan 💬 [1] AVPR2 💬 [3] Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[4] 67, 72, 86, 225 💬
40VIAGRA[1] Sildenafil[1] Sildenafil 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[3] 86, 96, 225 💬