Drug Description in Trials / DrugBank / KEGG DRUG

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No.

Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

1

Blinded CDCA 250 mg TID

[1] Chenodeoxycholic acid

[1] Chenodiol 💬

[1] NR1H4 💬

[1] Bile secretion 💬

[1] 263 💬

2

-

-

-

-

[2] 46, 263 💬

3

[1] Chenodeoxycholic acid

[1] Chenodiol 💬

[1] NR1H4 💬

[1] Bile secretion 💬

[1] 263 💬

4

CDCA Weight-Based Dose TID

[1] Chenodeoxycholic acid

[1] Chenodiol 💬

[1] NR1H4 💬

[1] Bile secretion 💬

[1] 263 💬

5

Chenodeoxycholic acid

[1] Chenodeoxycholic acid

[1] Chenodiol 💬

[1] NR1H4 💬

[1] Bile secretion 💬

[4] 20, 96, 234, 263 💬

6

-

-

-

-

[1] 263 💬

7

[1] Lovastatin 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬

Disease ID	Name
6	Parkinson disease
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
79	Homozygous familial hypercholesterolemia
156	Rett syndrome
160	Congenital ichthyosis
195	Noonan syndrome
206	Fragile X syndrome
263	Cerebrotendinous xanthomatosis
280	Huge arteriovenous malformation with cervicofacial or limb lesion
310	Congenital anomalies syndrome

8

Mutation Analysis

-

-

-

-

[1] 263 💬

9

Open-Label CDCA 250 mg TID

[1] Chenodeoxycholic acid

[1] Chenodiol 💬

[1] NR1H4 💬

[1] Bile secretion 💬

[1] 263 💬

10

Rescue Medication CDCA 250 mg TID

[1] Chenodeoxycholic acid

[1] Chenodiol 💬

[1] NR1H4 💬

[1] Bile secretion 💬

[1] 263 💬