Drug Description in Trials / DrugBank / KEGG DRUG

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No.

Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

1

[1] Abacavir 💬

-

-

[4] 2, 135, 265, 325 💬

2

[1] Baricitinib

[1] Baricitinib 💬

[2] JAK1,
JAK2 💬

[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬

[13] 2, 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
41	Giant cell arteritis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
50	Dermatomyositis
51	Scleroderma
53	Sjogren syndrome
93	Primary biliary cholangitis
107	Juvenile idiopathic arthritis
162	Pemphigoid
265	Lipodystrophy
269	Pyogenic arthritis
325	Hereditary autoinflammatory syndrome

3

[1] Emtricitabine

[1] Emtricitabine 💬

-

-

[4] 25, 93, 265, 325 💬

4

[1] Lamivudine 💬

-

-

[7] 2, 26, 42, 46, 135, 265, 325 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
26	HTLV-1-associated myelopathy
42	Polyarteritis nodosa
46	Malignant rheumatoid arthritis
135	Aicardi syndrome
265	Lipodystrophy
325	Hereditary autoinflammatory syndrome

5

-

-

-

-

[6] 46, 49, 50, 93, 107, 325 💬

6

Reverse transcriptase inhibitors: Zidovudine, Lamivudine, Abacavir

[3] Abacavir,
Lamivudine,
Zidovudine

[3] Lamivudine ,
Zidovudine ,
Abacavir 💬

-

-

[1] 325 💬

7

[2] Tenofovir,
Tenofovir disoproxil

[1] Tenofovir 💬

-

-

[6] 2, 13, 25, 93, 265, 325 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
13	Multiple sclerosis/Neuromyelitis optica
25	Progressive multifocal leukoencephalopathy
93	Primary biliary cholangitis
265	Lipodystrophy
325	Hereditary autoinflammatory syndrome

8

Tenofovir (TDF) and Emtricitabine (FTC)

[2] Emtricitabine,
Tenofovir

[2] Emtricitabine ,
Tenofovir 💬

-

-

[1] 325 💬

9

-

-

-

-

[3] 2, 127, 325 💬

10

[1] Zidovudine 💬

-

-

[6] 25, 26, 135, 265, 325, 331 💬

Disease ID	Name
25	Progressive multifocal leukoencephalopathy
26	HTLV-1-associated myelopathy
135	Aicardi syndrome
265	Lipodystrophy
325	Hereditary autoinflammatory syndrome
331	Idiopathic multicentric castleman disease