Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1ACE Inhibitor or Angiotensin receptor antagonist[1] Angiotensin II (isoleucine5-angiotensin II)[2] Angiotensin II (Angiotensin II),
Angiotensin II (Angiotensin II, Angiotensin II) 💬 		[2] AGTR1,
AGTR2 💬 		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 66 💬
2Angiotensin[1] Angiotensin II (isoleucine5-angiotensin II)[2] Angiotensin II (Angiotensin II),
Angiotensin II (Angiotensin II, Angiotensin II) 💬 		[2] AGTR1,
AGTR2 💬 		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[7] 17, 19, 46, 66, 86, 222, 224 💬
3Angiotensin blockade[1] Angiotensin II (isoleucine5-angiotensin II)[2] Angiotensin II (Angiotensin II),
Angiotensin II (Angiotensin II, Angiotensin II) 💬 		[2] AGTR1,
AGTR2 💬 		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 66 💬
4Angiotensin II[1] Angiotensin II (isoleucine5-angiotensin II)[2] Angiotensin II (Angiotensin II),
Angiotensin II (Angiotensin II, Angiotensin II) 💬 		[2] AGTR1,
AGTR2 💬 		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 66, 222 💬
5Angiotensin receptor blockers[1] Angiotensin II (isoleucine5-angiotensin II)[2] Angiotensin II (Angiotensin II),
Angiotensin II (Angiotensin II, Angiotensin II) 💬 		[2] AGTR1,
AGTR2 💬 		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 46 💬
6Angiotensin-(1-7)[1] Angiotensin II (isoleucine5-angiotensin II)[2] Angiotensin II (Angiotensin II),
Angiotensin II (Angiotensin II, Angiotensin II) 💬 		[2] AGTR1,
AGTR2 💬 		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 17 💬
7Angiotensin-converting enzyme (ACE) inhibitor[1] Angiotensin II (isoleucine5-angiotensin II)[2] Angiotensin II (Angiotensin II),
Angiotensin II (Angiotensin II, Angiotensin II) 💬 		[2] AGTR1,
AGTR2 💬 		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 224 💬
8Angiotensin-converting enzyme inhibitor(ACEI)[1] Angiotensin II (isoleucine5-angiotensin II)[2] Angiotensin II (Angiotensin II),
Angiotensin II (Angiotensin II, Angiotensin II) 💬 		[2] AGTR1,
AGTR2 💬 		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 224 💬
9Enalapril and other angiotensin converting enzyme inhibitors[2] Angiotensin II (isoleucine5-angiotensin II),
Enalapril		[3] Angiotensin II (Angiotensin II),
Angiotensin II (Angiotensin II, Angiotensin II),
Enalapril 💬 		[3] ACE,
AGTR1,
AGTR2 💬 		[18] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 19 💬
10Losartan and other angiotensin receptor blockers[2] Angiotensin II (isoleucine5-angiotensin II),
Losartan		[3] Angiotensin II (Angiotensin II),
Angiotensin II (Angiotensin II, Angiotensin II),
Losartan 💬 		[2] AGTR1,
AGTR2 💬 		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 19 💬
11Recombinant Human Angiotensin-Converting Enzyme 2[2] Alunacedase alfa (Recombinant Human Angiotensin-Converting Enzyme 2),
Angiotensin II (isoleucine5-angiotensin II)		[2] Angiotensin II (Angiotensin II),
Angiotensin II (Angiotensin II, Angiotensin II) 💬 		[2] AGTR1,
AGTR2 💬 		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
12Recombinant Human Angiotensin-converting enzyme 2 (ACE2), APN01[2] Alunacedase alfa (Recombinant Human Angiotensin-Converting Enzyme 2),
Angiotensin II (isoleucine5-angiotensin II)		[2] Angiotensin II (Angiotensin II),
Angiotensin II (Angiotensin II, Angiotensin II) 💬 		[2] AGTR1,
AGTR2 💬 		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
13Renin Angiotensin system (RAS) blockade or Inhibitors of sodium glucose transporter 2 (SGLT2i)[2] Angiotensin II (isoleucine5-angiotensin II),
Dextrose, unspecified form		[2] Angiotensin II (Angiotensin II),
Angiotensin II (Angiotensin II, Angiotensin II) 💬 		[2] AGTR1,
AGTR2 💬 		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 66 💬
14Symptomatic treatment (Converting Enzyme inhibitor, Angiotensin II, Anti-renin, Aldosterone antagonist diuretic, Beta blocker, Calcium inhibitor, statin)[3] Aldosterone,
Angiotensin II (isoleucine5-angiotensin II),
Calcium		[3] Angiotensin II (Angiotensin II),
Angiotensin II (Angiotensin II, Angiotensin II),
Aldosterone 💬 		[3] AGTR1,
AGTR2,
NR3C2 💬 		[17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 222 💬