| 1 | Amitriptyline, fluoxetine and tramadol alone (control group) | [3]  Amitriptyline Amitriptyline, Fluoxetine (Nra-fluoxetine), Tramadol | [3]  Fluoxetine 
                
                    Fluoxetine
                
             (Fluoxetine, Fluoxetine), 
                
                    Amitriptyline
                
            , 
                
                    Tramadol
                
             💬
 | [3]  OPRM1 OPRM1, SLC6A2, SLC6A4 💬
 | [5]  Estrogen signaling pathway Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬 | [1]  78 78 💬
 | 
| 2 | FLUOXETINE | [1]  Fluoxetine Fluoxetine (Nra-fluoxetine) | [1]  Fluoxetine 
                
                    Fluoxetine
                
             (Fluoxetine, Fluoxetine) 💬
 | [1]  SLC6A4 SLC6A4 💬
 | [2]  Serotonergic synapse Serotonergic synapse, Synaptic vesicle cycle 💬 | [4]  13 13, 17, 78, 86 💬
 | 
| 3 | FLUOXETINE HYDROCHLORIDE | [1]  Fluoxetine Fluoxetine (Nra-fluoxetine) | [1]  Fluoxetine 
                
                    Fluoxetine
                
             (Fluoxetine, Fluoxetine) 💬
 | [1]  SLC6A4 SLC6A4 💬
 | [2]  Serotonergic synapse Serotonergic synapse, Synaptic vesicle cycle 💬 | [1]  13 13 💬
 | 
| 4 | Sc recombinant growth hormone + amitriptyline, fluoxetine and tramadol (treated group) | [4]  Amitriptyline Amitriptyline, Fluoxetine (Nra-fluoxetine), Somatotropin, Tramadol | [3]  Fluoxetine 
                
                    Fluoxetine
                
             (Fluoxetine, Fluoxetine), 
                
                    Amitriptyline
                
            , 
                
                    Tramadol
                
             💬
 | [3]  OPRM1 OPRM1, SLC6A2, SLC6A4 💬
 | [5]  Estrogen signaling pathway Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬 | [1]  78 78 💬
 |