Drug Description in Trials / DrugBank / KEGG DRUG

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No.

Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

1

Encapsulated Simvastatin tablets

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[1] 13 💬

2

Ezetimibe+Simvastatin Drug Combination

[2] Ezetimibe (Ezetimibe and Simvastatin),
Simvastatin (Simvastatin Tablets)

[2] Simvastatin (Simvastatin),
Ezetimibe 💬

[2] HMGCR,
NPC1L1 💬

[5] AMPK signaling pathway, Bile secretion, Fat digestion and absorption, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[1] 49 💬

3

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[21] 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬

Disease ID	Name
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
15	Inclusion body myositis
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
66	IgA nephropathy
79	Homozygous familial hypercholesterolemia
86	Pulmonary arterial hypertension
89	Lymphangioleiomyomatosis
94	Primary sclerosing cholangitis
158	Tuberous sclerosis
160	Congenital ichthyosis
162	Pemphigoid
195	Noonan syndrome
265	Lipodystrophy
288	Autoimmune acquired coagulation factor deficiency
298	Hereditary pancreatitis
299	Cystic fibrosis
310	Congenital anomalies syndrome

4

Simvastatin 20 mg

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[1] 46 💬

5

Simvastatin 20mg/5ml Oral Suspension

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[1] 34 💬

6

Simvastatin 40 mg

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[1] 86 💬

7

Simvastatin 40 mg film-coated tablets

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[1] 13 💬

8

Simvastatin 40 mg tablets

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[1] 86 💬

9

Simvastatin 40mg

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[1] 94 💬

10

Simvastatin Alternova

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[1] 13 💬

11

Simvastatin in relapsing remitting multiple sclerosis

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[1] 13 💬

12

Simvastatin Susp.

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[1] 310 💬

13

Simvastatin treatment for 28 days

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[1] 299 💬

14

Simvastatin-ratiopharm

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[1] 162 💬

15

Simvastatin-ratiopharm®

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[1] 162 💬

16

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[1] 13 💬

17

Simvastatina Sandoz 40 mg comprimidos recubiertos con película EFG

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[1] 13 💬

18

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[3] 6, 13, 288 💬

19

Simvastatine Sandoz 40 mg filmomhulde tabletten

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[1] 13 💬

20

Simvastatine Sandoz 40mg deelbare filmomhulde tabletten

[1] Simvastatin (Simvastatin Tablets)

[1] Simvastatin (Simvastatin) 💬

[1] HMGCR 💬

[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬

[1] 13 💬