Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Bosentan
(Tracleer)		[1] Bosentan (Tracleer)[2] Bosentan (Tracleer),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
2Bosentan (Tracleer)[1] Bosentan (Tracleer)[2] Bosentan (Tracleer),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51 💬
3Bosentan 125 mg
(Tracleer)		[1] Bosentan (Tracleer)[2] Bosentan (Tracleer),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51 💬
4Bosentan 62.5 mg
(Tracleer)		[1] Bosentan (Tracleer)[2] Bosentan (Tracleer),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51 💬
5Bosentan administration
(Tracleer)		[1] Bosentan (Tracleer)[2] Bosentan (Tracleer),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
6Bosentan and Sildenafil
(Tracleer)		[2] Bosentan (Tracleer),
Sildenafil		[3] Bosentan (Tracleer),
Bosentan ,
Sildenafil 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
7Bosentan group
(Tracleer)		[1] Bosentan (Tracleer)[2] Bosentan (Tracleer),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51 💬
8BOSENTAN MONOHIDRATO
(Tracleer)		[1] Bosentan (Tracleer)[2] Bosentan (Tracleer),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
9Bosentan monohydrat
(Tracleer)		[1] Bosentan (Tracleer)[2] Bosentan (Tracleer),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
10BOSENTAN MONOHYDRATE
(Tracleer)		[1] Bosentan (Tracleer)[2] Bosentan (Tracleer),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 51, 84, 86, 88 💬
11BOSENTAN MYLAN
(Tracleer)		[1] Bosentan (Tracleer)[2] Bosentan (Tracleer),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 41 💬
12Bosentan, Ambrisentan
(Tracleer)		[2] Ambrisentan,
Bosentan (Tracleer)		[3] Bosentan (Tracleer),
Ambrisentan ,
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
13Duo-Therapy with Sildenafil + Bosentan
(Tracleer)		[2] Bosentan (Tracleer),
Sildenafil		[3] Bosentan (Tracleer),
Bosentan ,
Sildenafil 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
14ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)
(Tracleer)		[4] Bosentan (Tracleer),
Macitentan,
Sildenafil,
Tadalafil		[5] Bosentan (Tracleer),
Tadalafil ,
Bosentan ,
Sildenafil ,
Macitentan 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
15Observational study with patients treated with Tracleer, Ventavis, Veletri, Opsumit and/or Uptravi[4] Epoprostenol,
Iloprost,
Macitentan,
Selexipag		[4] Epoprostenol ,
Iloprost ,
Selexipag ,
Macitentan 💬 		[3] EDNRA,
EDNRB,
PTGIR 💬 		[10] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Platelet activation, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
16Sildenafil 20mg and Bosentan 62.5mg
(Tracleer)		[2] Bosentan (Tracleer),
Sildenafil		[3] Bosentan (Tracleer),
Bosentan ,
Sildenafil 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 51, 86 💬
17Sildenafil singly or in association with Bosentan
(Tracleer)		[2] Bosentan (Tracleer),
Sildenafil		[3] Bosentan (Tracleer),
Bosentan ,
Sildenafil 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
18Tracleer[1] Bosentan (Tracleer)[2] Bosentan (Tracleer),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 13, 51, 84, 85, 86, 88, 210, 211 💬
19TRACLEER 125MG 56CPR RIV.[1] Bosentan (Tracleer)[2] Bosentan (Tracleer),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 88 💬
20TRACLEER 62,5 mg comprimidos recubiertos con película[1] Bosentan (Tracleer)[2] Bosentan (Tracleer),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
21TRACLEER 62,5MG 56CPR RIV.[1] Bosentan (Tracleer)[2] Bosentan (Tracleer),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
22TRACLEER*125MG 56CPR RIV.[1] Bosentan (Tracleer)[2] Bosentan (Tracleer),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 51, 86 💬
23TRACLEER*56CPR RIV 125MG[1] Bosentan (Tracleer)[2] Bosentan (Tracleer),
Bosentan 💬 		[2] EDNRA,
EDNRB 💬 		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 86, 88 💬
24Tracleer®----[1] 86 💬