| 1 | **Comment**- IMP inhalation solution identical to ventavis inhalation solution, but IMP is in a different volume presentation. Please see covering letter. | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 2 | Aerosolized iloprost (Ventavis) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 3 | Commercial Ventavis® (iloprost) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 4 | Iloprost (Ventavis) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [4]  51 51, 84, 85, 86 💬
 | 
| 5 | Iloprost (5 µg) (Ventavis) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 6 | Iloprost (Ventavis BAYQ6256) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 7 | Iloprost (Ventavis inhaled, BAYQ6256) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 8 | Iloprost (Ventavis, BAYQ 6256) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 9 | Iloprost (Ventavis, BAYQ6256) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 10 | Iloprost (Ventavis®) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 11 | Iloprost Inhalation Solution (Ventavis) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [2]  85 85, 86 💬
 | 
| 12 | Iloprost Injection, for intravenous use (Ventavis) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  51 51 💬
 | 
| 13 | Iloprost low dose (Ventavis) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  51 51 💬
 | 
| 14 | Iloprost PD-15 (Ventavis) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 15 | Iloprost PD-6 (Ventavis) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 16 | ILOPROST SALE DI TROMETAMOLO (Ventavis) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  51 51 💬
 | 
| 17 | Iloprost therapy up to 2 ng/kg x min (Ventavis) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  51 51 💬
 | 
| 18 | ILOPROST TROMETAMOL (Ventavis) | [2]  Iloprost Iloprost (Ventavis), Tromethamine | [2]  Tromethamine 
                
                    Tromethamine
                
            , 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  51 51 💬
 | 
| 19 | Iloprost,(Ventavis, BAYQ6256) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 20 | Inhaled Iloprost (5 µg) (Ventavis) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 21 | Inhaled iloprost (Ventavis, BAYQ6256) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 22 | Lloprost(Ventavis,BAYQ6252, 10 µg/mL) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 23 | Lloprost(Ventavis,BAYQ6252, 20 µg/mL) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 24 | Observational study with patients treated with Tracleer, Ventavis, Veletri, Opsumit and/or Uptravi | [4]  Epoprostenol Epoprostenol, Iloprost (Ventavis), Macitentan, Selexipag | [4]  Epoprostenol 
                
                    Epoprostenol
                
            , 
                
                    Iloprost
                
             (Ventavis), 
                
                    Selexipag
                
            , 
                
                    Macitentan
                
             💬
 | [3]  EDNRA EDNRA, EDNRB, PTGIR 💬
 | [10]  Calcium signaling pathway Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Platelet activation, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬 | [1]  86 86 💬
 | 
| 25 | Ventavis | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 26 | Ventavis (Iloprost, BAYQ6256) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 27 | Ventavis 10 | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 | 
| 28 | Ventavis(Iloprost) | [1]  Iloprost Iloprost (Ventavis) | [1]  Iloprost 
                
                    Iloprost
                
             (Ventavis) 💬
 | [1]  PTGIR PTGIR 💬
 | [3]  Neuroactive ligand-receptor interaction Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬 | [1]  86 86 💬
 |