Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(Pyr1)apelin-13----[1] 86 💬
210 milligram (mg) fampridine-SR (4-aminopyridine, 4-AP)[1] Dalfampridine (4-AP)[1] Dalfampridine 💬 [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬 		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[1] 13 💬
3100 mg AP1189----[2] 46, 222 💬
415 mg fampridine-SR (4-aminopyridine, 4-AP)[1] Dalfampridine (4-AP)[1] Dalfampridine 💬 [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬 		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[1] 13 💬
51500mg mesalazine pellets
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
620 mg fampridine-SR (4-aminopyridine, 4-AP)[1] Dalfampridine (4-AP)[1] Dalfampridine 💬 [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬 		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[1] 13 💬
720 mg sildenafil citrate by mouth
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
8250mg mesalazine pellets
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
93K3A-APC Protein----[1] 2 💬
104-AP[1] Dalfampridine (4-AP)[1] Dalfampridine 💬 [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬 		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[1] 13 💬
115% sildenafil cream
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 50 💬
1250 mg AP1189----[1] 46 💬
13500mg mesalazine pellets
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
146abeta - apomorphine-10,11-diol hydrochloride hemihydrate[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
156aß - apomorphine-10,11-diol hydrochloride hemihydrate[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
16750mg mesalazine pellets
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
1790 mg hydrocortisone acetate suppository with Sephure suppository applicator[3] Acetate,
Hydrocortisone (Apres Peel Soothing Balm),
Hydrocortisone acetate		[2] Hydrocortisone ,
Hydrocortisone acetate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 97 💬
1890 mg idrocortisone acetato in supposta con appli----[1] 97 💬
1990 mg idrocortisone acetato in supposta con applicatore per supposte Sephure----[1] 97 💬
20Access program - sildenafil citrate, Viagra, Revatio
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
21ADSVF application in the right hand----[1] 51 💬
22Allo-APZ2-EB----[1] 36 💬
23Allo-APZ2-OTS----[1] 36 💬
24Any other approved Antiepileptic Drug----[1] 144 💬
25AODG (Apigenin-7-O-glucuronide)[1] Apigenin (Apigenin)---[1] 97 💬
26AP----[4] 2, 6, 13, 299 💬
27AP-101----[1] 2 💬
28AP-CD/LD----[1] 6 💬
29AP-PA02----[1] 299 💬
30AP01----[1] 85 💬
31AP09004----[1] 6 💬
32AP1189----[2] 46, 222 💬
33AP1189, 100 mg----[1] 46 💬
34AP1189, 60 mg----[1] 46 💬
35AP1189, 80 mg----[1] 46 💬
36AP1903----[3] 60, 285, 326 💬
37AP1903 A594----[3] 60, 285, 326 💬
38Apabetalone[1] Apabetalone (Apabetalone)[1] Apabetalone (Apabetalone) 💬 [4] BRD2,
BRD3,
BRD4,
BRDT 💬 		-[1] 86 💬
39Apadamtase alfa[1] Apadamtase alfa (Apadamtase alfa)---[1] 64 💬
40Apademtase alfa----[1] 64 💬
41APCC, aPCC + TXA----[1] 288 💬
42APD334----[5] 93, 96, 97, 98, 269 💬
43APD334 L-arginine[2] Arginine,
L-arginine		[1] Arginine 💬 --[1] 97 💬
44APD371----[1] 96 💬
45APD421----[1] 107 💬
46APD811----[1] 86 💬
47Apelin----[1] 86 💬
48API----[2] 231, 299 💬
49API-AAT----[1] 231 💬
50API-AAT, AD00370, ARC-AAT, API drug Substance----[1] 231 💬
51Apigenin[1] Apigenin (Apigenin)---[2] 6, 97 💬
52Apitegromab[1] Apitegromab (Apitegromab)[1] Apitegromab (Apitegromab) 💬 [1] MSTN 💬 [1] Cytokine-cytokine receptor interaction 💬[1] 3 💬
53Apitox - pure honeybee toxin----[1] 13 💬
54Apixaban[1] Apixaban (Mar-apixaban)[1] Apixaban (Apixaban) 💬 [1] F10 💬 [1] Complement and coagulation cascades 💬[1] 222 💬
55APL-130277----[1] 6 💬
56APL-1401----[1] 97 💬
57APL-2----[5] 2, 61, 62, 66, 222 💬
58APLA12----[1] 46 💬
59Aplindore[1] Aplindore (Aplindore)---[1] 6 💬
60Aplindore MR tablets[1] Aplindore (Aplindore)---[1] 6 💬
61APO-go----[1] 6 💬
62APO-go®----[1] 6 💬
63APO-P001----[1] 2 💬
64APOKINON----[1] 6 💬
65APOKYN[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
66Apomor----[1] 6 💬
67Apomorfina[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
68APOMORFINA CLORIDRATO[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
69Apomorp----[1] 6 💬
70Apomorphine[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 5, 6, 7 💬
71Apomorphine 0.25% (2.5mg/ml)[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
72Apomorphine HCl injection[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
73APOMORPHINE HYDROCHLORIDE[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
74Apomorphine hydrochloride 1.8mg inhalation powder, pre-dispensed[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
75Apomorphine hydrochloride 2.8mg inhalation powder, pre-dispensed[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
76Apomorphine hydrochloride 4.0 mg inhalation powder, pre-dispensed[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
77Apomorphine hydrochloride 5.8 mg inhalation powder, pre-dispensed[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
78APOMORPHINE HYDROCHLORIDE HEMIHYDRATE[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
79Apomorphine Hydrocloride[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
80Apomorphine Hydrocloride Hemihydrate[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
81Apomorphine infusion[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
82Apomorphine Injectable Solution[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
83Apomorphine Nasal Powder[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
84APORON----[1] 6 💬
85ApoTamox 10mg----[1] 111 💬
86Application of Adalimumab[1] Adalimumab[1] Adalimumab 💬 [1] TNF 💬 [67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 96 💬
87Apply VEREGEN ® 10 % on a randomized area and the moisturizing cream of the other side[1] Sinecatechins[1] Sinecatechins 💬 --[1] 160 💬
88Apraclonidine[1] Apraclonidine (Apraclonidine Ophthalmic)[1] Apraclonidine (Apraclonidine) 💬 [3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 11 💬
89Apraclonidine Hcl 0.5% Oph Soln[1] Apraclonidine (Apraclonidine Ophthalmic)[1] Apraclonidine (Apraclonidine) 💬 [3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 11 💬
90Apratastat[1] Apratastat (Apratastat)[1] Apratastat (Apratastat) 💬 [2] ADAM17,
MMP13 💬 		[7] Alzheimer disease, Coronavirus disease - COVID-19, Epithelial cell signaling in Helicobacter pylori infection, IL-17 signaling pathway, Notch signaling pathway, Parathyroid hormone synthesis, secretion and action, Relaxin signaling pathway 💬[1] 46 💬
91Apremilast[1] Apremilast (Teva-apremilast)[1] Apremilast (Apremilast) 💬 [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬 		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[7] 46, 50, 56, 97, 107, 162, 271 💬
92Apremilast (CC-10004)[1] Apremilast (Teva-apremilast)[1] Apremilast (Apremilast) 💬 [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬 		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[1] 56 💬
93Apremilast 10 mg[1] Apremilast (Teva-apremilast)[1] Apremilast (Apremilast) 💬 [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬 		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[2] 56, 107 💬
94Apremilast 20 mg[1] Apremilast (Teva-apremilast)[1] Apremilast (Apremilast) 💬 [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬 		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[3] 46, 56, 107 💬
95Apremilast 30 mg[1] Apremilast (Teva-apremilast)[1] Apremilast (Apremilast) 💬 [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬 		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[3] 46, 56, 107 💬
96Apremilast 30mg[1] Apremilast (Teva-apremilast)[1] Apremilast (Apremilast) 💬 [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬 		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[1] 50 💬
97Apremilast tablet 20 mg[1] Apremilast (Teva-apremilast)[1] Apremilast (Apremilast) 💬 [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬 		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[1] 271 💬
98Apremilast tablet 30 mg BID[1] Apremilast (Teva-apremilast)[1] Apremilast (Apremilast) 💬 [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬 		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[1] 271 💬
99APRINOX----[1] 67 💬
100Apriso 0.375G ER CAP----[1] 97 💬
101APRISO 375 mg extended-release capsules[1] Manganese citrate---[1] 97 💬
102AProArt----[1] 65 💬
103Aprotinin[1] Aprotinin (Aprotinin bovine)[1] Aprotinin (Aprotinin) 💬 --[1] 28 💬
104Aprovel[1] Irbesartan (Aprovel)[1] Irbesartan 💬 [1] AGTR1 💬 [16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 167 💬
105Aprovel (150 mg)[1] Irbesartan (Aprovel)[1] Irbesartan 💬 [1] AGTR1 💬 [16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 222 💬
106Aprovel 150 mg Tablets[1] Irbesartan (Aprovel)[1] Irbesartan 💬 [1] AGTR1 💬 [16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 222 💬
107APT-1011----[1] 98 💬
108APT-1011 - 3 mg----[1] 98 💬
109APT-1011 3 mg HS----[1] 98 💬
110APVO210----[1] 97 💬
111Autologous apoptotic cells injection----[1] 46 💬
112Autologous CD34+ HSCs transduced ex vivo with CD11B LV encoding human IDS tagged with ApoEII----[1] 19 💬
113Azathioprine OR Mesalazine
(Apriso)		[2] Azathioprine (Apo-azathioprine),
Mesalazine (Apriso)		[2] Azathioprine ,
Mesalamine (Apriso) 💬 		--[1] 96 💬
114Bosentan and Sildenafil
(Aphrodil)		[2] Bosentan (Apo-bosentan),
Sildenafil (Apo-sildenafil)		[3] Bosentan ,
Bosentan ,
Sildenafil (Aphrodil) 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
115BPR277 ointment (controlled application)----[1] 160 💬
116Brimonidine Tartrate Posterior Segment Drug Delivery System (Brimo PS DDS) Applicator System[1] Brimonidine (Apo-brimonidine-timop)[1] Brimonidine 💬 [3] ADRA2A,
ADRA2B,
ADRA2C 💬 		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 90 💬
117Cabotegravir
(APRETUDE)		[1] Cabotegravir (Apretude)[1] Cabotegravir (APRETUDE) 💬 --[1] 256 💬
118Cabotegravir (CAB) tablet
(APRETUDE)		[1] Cabotegravir (Apretude)[1] Cabotegravir (APRETUDE) 💬 --[1] 256 💬
119Cabotegravir - Injectable Suspension (CAB LA)
(APRETUDE)		[1] Cabotegravir (Apretude)[1] Cabotegravir (APRETUDE) 💬 --[1] 256 💬
120Canakinumab (WHO approval pending)[1] Canakinumab[1] Canakinumab 💬 [1] IL1B 💬 [44] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection 💬[1] 106 💬
121Cannabidiol Oral Solution, is known as Epidyolex 100 mg/mL oral solution and is the approved name in the EU. Epidiolex (cannabidiol) oral solution is the approved name in the US.[1] Cannabidiol[1] Cannabidiol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 158 💬
122Captopril
(Apopril)		[1] Captopril (Apo-capto Tab 100mg)[1] Captopril (Apopril) 💬 [1] ACE 💬 [6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[2] 17, 86 💬
123CBD - Oral Solution, is known as Epidiolex, and is the approved name in the USA.[1] Cannabidiol[1] Cannabidiol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[2] 140, 144 💬
124CBD - Oral Solution, is known as Epidyolex, and is the approved name[1] Cannabidiol[1] Cannabidiol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 156 💬
125CBD - Solution Orale, conosciuto come Epidiolex, questo è il nome approvato negli Stati Uniti[1] Cannabidiol[1] Cannabidiol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 156 💬
126CBD Oral solution, is known as Epidyolex and is the approved name in the EU[1] Cannabidiol[1] Cannabidiol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 156 💬
127CBD soluzione orale nota come Epidyolex e con tale nome è stato approvato in UE[1] Cannabidiol[1] Cannabidiol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 156 💬
128CBD-Oral Solution, is known as Epidiolex, and is the approved name in the USA.[1] Cannabidiol[1] Cannabidiol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 158 💬
129Continuous Apomorphine infusion[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
130Conventional treatment (glucocoticoid, immunosupressive drugs and/or mesalazine)
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[2] 96, 97 💬
131Corticosteroids (Aprednislon)----[1] 63 💬
132CR002 Liquid API[1] CR002---[1] 299 💬
133Crocin and Apigenin[2] Apigenin (Apigenin),
Crocin		---[1] 6 💬
134D.3.2 Product code where applicable13:----[1] 193 💬
135Delayed and extended release mesalazine
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
136Dopaminergic Agonist + Apomorphine[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
137Duo-Therapy with Sildenafil + Bosentan
(Aphrodil)		[2] Bosentan (Apo-bosentan),
Sildenafil (Apo-sildenafil)		[3] Bosentan ,
Bosentan ,
Sildenafil (Aphrodil) 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
138EB-101 Surgical application of RDEB wounds----[1] 36 💬
139Epidyolex and is the approved name in the EU[1] Cannabidiol[1] Cannabidiol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 156 💬
140ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)
(Aphrodil)		[4] Bosentan (Apo-bosentan),
Macitentan,
Sildenafil (Apo-sildenafil),
Tadalafil (Apo-tadalafil Pah)		[5] Bosentan ,
Tadalafil ,
Bosentan ,
Sildenafil (Aphrodil),
Macitentan 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
141EU-approved RoActemra[1] Tocilizumab[1] Tocilizumab 💬 [1] IL6R 💬 [12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46 💬
142EUR-1008 (APT-1008)----[1] 299 💬
143EUR-1008 (APT-1008) High Dose----[1] 298 💬
144EUR-1008 (APT-1008) Low Dose----[1] 298 💬
145Ex-vivo approach concerning 25 patients----[2] 102, 299 💬
146Firategrast (USAN approved name)[1] Firategrast[1] Firategrast 💬 [1] ITGA4 💬 [14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection 💬[1] 13 💬
147G04BE03- Sildenafil - sildenafil (citrato)
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
148Group 3: ustekinumab approximately 6 mg/kg[1] Ustekinumab[1] Ustekinumab 💬 [3] IL12A,
IL12B,
IL23A 💬 		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[1] 96 💬
149Hydrokortison APL kapsel 2,5 mg----[1] 83 💬
150In-vitro approach concerning 25 patients----[2] 102, 299 💬
151Injection of apomorphine[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
152Interferon beta-1a (current approved manufacturing process invloving FBS)[2] Human interferon beta,
Interferon beta-1a		[1] Interferon beta-1a 💬 [2] IFNAR1,
IFNAR2 💬 		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[1] 13 💬
153Investigators Choice of Approved AED----[1] 144 💬
154Investigators choice of approved AEDs----[1] 144 💬
155Irbesartan tablets (Approved in the USA. Reference listed drug Avapro) NDC # 43547-0374-03[1] Irbesartan (Aprovel)[1] Irbesartan 💬 [1] AGTR1 💬 [16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 66, 222 💬
156Irbesartan tablets (NDC# 31722-729-30 approved in the United states)[1] Irbesartan (Aprovel)[1] Irbesartan 💬 [1] AGTR1 💬 [16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 222 💬
157Irbesartan tablets (NDC# 43547-0374-03 and NDC 43547-374-09, approved in the USA) Generic tablets distributed by Solco Healthcare US, LLC[1] Irbesartan (Aprovel)[1] Irbesartan 💬 [1] AGTR1 💬 [16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 222 💬
158IV Apomorphine[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
159Kamada-API----[1] 231 💬
160Lithium Apogepha[2] Lithium carbonate (Apo-lithium Carbonate),
Lithium citrate		[2] Lithium carbonate ,
Lithium citrate 💬 		--[1] 2 💬
161Locally approved intravenous contrast medium for contrast enhanced magnetic resonance imaging (MRI)----[1] 13 💬
162Mesalazine
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[3] 46, 96, 97 💬
163Mesalazine (3,600 mg)
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
164Mesalazine (Asacol®)
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
165Mesalazine (Mesalamine)
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 96 💬
166Mesalazine - TID 1000 mg
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
167Mesalazine - TID 2x 500 mg
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
168Mesalazine 1000 mg gastro-resistant tablets
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
169Mesalazine 250Mg
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
170Mesalazine 250Mg Tablet and nitazoxanide 500Mg Oral Tablet
(Apriso)		[2] Mesalazine (Apriso),
Nitazoxanide		[2] Mesalamine (Apriso),
Nitazoxanide 💬 		--[1] 97 💬
171Mesalazine 4G Enema
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
172Mesalazine 500 mg gastro-resistant tablets (Salofa
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
173Mesalazine 500 mg gastro-resistant tablets (Salofalk® 500 mg)
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
174Mesalazine EC 500 mg
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 96 💬
175Mesalazine Enema
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
176Mesalazine liquid enema
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
177Mesalazine slow-release granules
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
178Mesalazine Sustained-Release Tablets
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 96 💬
179Mesalazine tablet
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
180Mesalazine tablets
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 96 💬
181Mesalazine with hydrocortisone sodium succinate
(Apriso)		[2] Hydrocortisone (Apres Peel Soothing Balm),
Mesalazine (Apriso)		[2] Hydrocortisone ,
Mesalamine (Apriso) 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[1] 97 💬
182Mesalazine, Tripterygium glycosides
(Apriso)		[2] Mesalazine (Apriso),
Tripterygium wilfordii whole		[1] Mesalamine (Apriso) 💬 --[1] 96 💬
183MMX mesalamine/ mesalazine
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
184MMX Mesalamine/Mesalazine
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
185MMX Mesalamine/Mesalazine (High Dose)
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
186MMX Mesalamine/Mesalazine (Low Dose)
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
187Mono-Therapy with Sildenafil
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
188Non applicabile----[4] 13, 49, 51, 256 💬
189Non applicable----[2] 10, 19 💬
190Oral sildenafil
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
191Overencapsulated mesalazine tablets
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
192Part 1 Levulan surface application----[1] 34 💬
193Part 1 Levulan surface application twice----[1] 34 💬
194Part 1 Levulan surface application twice with microneedling----[1] 34 💬
195Patients' existing non-steroidal anti-inflammatory drug (NSAID) at approved doses----[1] 46 💬
196Pegcetacoplan (APL-2)[1] Pegcetacoplan[1] Pegcetacoplan 💬 [1] C3 💬 [17] Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagosome, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬[3] 2, 61, 62 💬
197Pharmacologic approaches to glycemic treatment----[1] 298 💬
198Primary Cervical Dystonia (Trihexyphenidyl)
(Apo-trihex)		[1] Trihexyphenidyl (Aparkane Tab 2mg)[1] Trihexyphenidyl (Apo-trihex) 💬 [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 6 💬
199Recombinant Human Angiotensin-converting enzyme 2 (ACE2), APN01[2] Alunacedase alfa,
Angiotensin II		[2] Angiotensin II ,
Angiotensin II 💬 		[2] AGTR1,
AGTR2 💬 		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
200Recombinant Human Apolipoprotein----[1] 79 💬
201Recombinant Human Apolipoprotein A-I----[1] 79 💬
202Recombinant Human Apolipoprotein A-I/Phospholipids Complex[1] Omega-3 fatty acids---[1] 79 💬
203Recombinant human apolipoprotein a1----[1] 79 💬
204Riociguat granules 0.3% for oral application[1] Riociguat[1] Riociguat 💬 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬 		[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86 💬
205S.c. apomorphine[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
206Sildenafil
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
207Sildenafil (50 mg)
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 85 💬
208Sildenafil (Acute-1 hour)
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 299 💬
209Sildenafil (as citrate)
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
210Sildenafil (REVATIO)
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
211Sildenafil (Revatio) 20 mg TID
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
212Sildenafil (Subchronic-4 weeks)
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 299 💬
213Sildenafil 20 mg tablets
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 278 💬
214Sildenafil 20mg
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[2] 51, 86 💬
215Sildenafil 20mg and Bosentan 62.5mg
(Aphrodil)		[2] Bosentan (Apo-bosentan),
Sildenafil (Apo-sildenafil)		[3] Bosentan ,
Bosentan ,
Sildenafil (Aphrodil) 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 51, 86 💬
216Sildenafil 40mg oral capsule
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 299 💬
217Sildenafil and Losartan
(Aphrodil)		[2] Losartan (Apo-losartan),
Sildenafil (Apo-sildenafil)		[2] Losartan ,
Sildenafil (Aphrodil) 💬 		[2] AGTR1,
PDE5A 💬 		[18] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Purine metabolism, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 85 💬
218Sildenafil by injection
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 210 💬
219SILDENAFIL CITRATE
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[4] 51, 85, 86, 225 💬
220Sildenafil citrate (UK-92,480)
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
221Sildenafil Filmtabletten
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
222Sildenafil Oral Suspension
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 294 💬
223Sildenafil singly or in association with Bosentan
(Aphrodil)		[2] Bosentan (Apo-bosentan),
Sildenafil (Apo-sildenafil)		[3] Bosentan ,
Bosentan ,
Sildenafil (Aphrodil) 💬 		[3] EDNRA,
EDNRB,
PDE5A 💬 		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
224Sildenafil therapy
(Aphrodil)		[1] Sildenafil (Apo-sildenafil)[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 51 💬
225Sitaxsentan and Sildenafil
(Aphrodil)		[2] Sildenafil (Apo-sildenafil),
Sitaxentan		[2] Sitaxentan ,
Sildenafil (Aphrodil) 💬 		[2] EDNRA,
PDE5A 💬 		[9] Calcium signaling pathway, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
226Sodium tanshinone IIA sulfonate diluted with 5% glucose solution,20mg sildenafil citrate by mouth
(Aphrodil)		[2] Dextrose, unspecified form,
Sildenafil (Apo-sildenafil)		[1] Sildenafil (Aphrodil) 💬 [1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86 💬
227SPD476 (mesalazine)
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
228SPD476 is a polymeric matrix formulation that displays both delayed- and extended-release of mesalazine
(Apriso)		[1] Mesalazine (Apriso)[1] Mesalamine (Apriso) 💬 --[1] 97 💬
229Spironolactone captopril carvedilol
(Apopril)		[3] Captopril (Apo-capto Tab 100mg),
Carvedilol (Apo-carvedilol),
Spironolactone (Apo-spirozide Tab)		[3] Captopril (Apopril),
Carvedilol ,
Spironolactone 💬 		[7] ACE,
ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2,
NR3C2 💬 		[19] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Chagas disease, Chemical carcinogenesis - receptor activation, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dilated cardiomyopathy, Gap junction, Hypertrophic cardiomyopathy, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Renin-angiotensin system, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86 💬
230Subcutaneous apomorphine[1] Apomorphine (Apomorphine Hydrocloride)[1] Apomorphine (Apomorphine) 💬 [2] DRD1,
DRD2 💬 		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6 💬
231Tadalafil and Sildenafil
(Aphrodil)		[2] Sildenafil (Apo-sildenafil),
Tadalafil (Apo-tadalafil Pah)		[2] Tadalafil ,
Sildenafil (Aphrodil) 💬 		[1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 113 💬
232Tezepelumab via APFS[1] Tezepelumab[1] Tezepelumab 💬 [1] TSLP 💬 [2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[1] 98 💬
233Tipranavir
(Aptivus)		[1] Tipranavir (Aptivus)[1] Tipranavir (Aptivus) 💬 --[1] 265 💬
234Trifluoperazine
(Apo-trifluoperazine)		[1] Trifluoperazine[2] Trifluoperazine maleate ,
Trifluoperazine (Apo-trifluoperazine) 💬 		[1] DRD2 💬 [8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 283, 284 💬
235Trihexyphenidyl
(Apo-trihex)		[1] Trihexyphenidyl (Aparkane Tab 2mg)[1] Trihexyphenidyl (Apo-trihex) 💬 [5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 5, 6 💬
236Ustekinumab (approximately 6 mg/kg)[1] Ustekinumab[1] Ustekinumab 💬 [3] IL12A,
IL12B,
IL23A 💬 		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[1] 49 💬
237Ustekinumab approximately 6 mg/kg (IV)[1] Ustekinumab[1] Ustekinumab 💬 [3] IL12A,
IL12B,
IL23A 💬 		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[1] 96 💬
238VOLANESORSEN SODIUM, ApoC-III Antisense Oligonucleotide[1] Volanesorsen[1] Volanesorsen 💬 [1] APOC3 💬 [2] Cholesterol metabolism, PPAR signaling pathway 💬[1] 265 💬