Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(Pyr1)apelin-13----[1] 86
210 milligram (mg) fampridine-SR (4-aminopyridine, 4-AP)[1] Dalfampridine (Synonym: 4-AP)[1] D04127 [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[1] 13
3100 mg AP1189----[2] 46, 222
415 mg fampridine-SR (4-aminopyridine, 4-AP)[1] Dalfampridine (Synonym: 4-AP)[1] D04127 [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[1] 13
51500mg mesalazine pellets
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
620 mg fampridine-SR (4-aminopyridine, 4-AP)[1] Dalfampridine (Synonym: 4-AP)[1] D04127 [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[1] 13
720 mg sildenafil citrate by mouth
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
8250mg mesalazine pellets
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
93K3A-APC Protein----[1] 2
104-AP[1] Dalfampridine (Synonym: 4-AP)[1] D04127 [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[1] 13
115% sildenafil cream
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 50
1250 mg AP1189----[1] 46
13500mg mesalazine pellets
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
146abeta - apomorphine-10,11-diol hydrochloride hemihydrate[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
156aß - apomorphine-10,11-diol hydrochloride hemihydrate[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
16750mg mesalazine pellets
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
1790 mg hydrocortisone acetate suppository with Sephure suppository applicator[3] Acetate,
Hydrocortisone (Synonym: Apres Peel Soothing Balm),
Hydrocortisone acetate		[2] D00088 ,
D00165 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
1890 mg idrocortisone acetato in supposta con appli----[1] 97
1990 mg idrocortisone acetato in supposta con applicatore per supposte Sephure----[1] 97
20Access program - sildenafil citrate, Viagra, Revatio
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
21ADSVF application in the right hand----[1] 51
22Allo-APZ2-EB----[1] 36
23Allo-APZ2-OTS----[1] 36
24Any other approved Antiepileptic Drug----[1] 144
25AODG (Apigenin-7-O-glucuronide)[1] Apigenin---[1] 97
26AP----[4] 2, 6, 13, 299
27AP-101----[1] 2
28AP-CD/LD----[1] 6
29AP-PA02----[1] 299
30AP01----[1] 85
31AP09004----[1] 6
32AP1189----[2] 46, 222
33AP1189, 100 mg----[1] 46
34AP1189, 60 mg----[1] 46
35AP1189, 80 mg----[1] 46
36AP1903----[3] 60, 285, 326
37AP1903 A594----[3] 60, 285, 326
38Apabetalone[1] Apabetalone[1] D11131 (Name: Apabetalone)[4] BRD2,
BRD3,
BRD4,
BRDT 💬		-[1] 86
39Apadamtase alfa[1] Apadamtase alfa---[1] 64
40Apademtase alfa----[1] 64
41APCC, aPCC + TXA----[1] 288
42APD334----[5] 93, 96, 97, 98, 269
43APD334 L-arginine[1] Arginine[1] D02982 --[1] 97
44APD371----[1] 96
45APD421----[1] 107
46APD811----[1] 86
47Apelin----[1] 86
48API----[2] 231, 299
49API-AAT----[1] 231
50API-AAT, AD00370, ARC-AAT, API drug Substance----[1] 231
51Apigenin[1] Apigenin---[2] 6, 97
52Apitegromab[1] Apitegromab[1] D11797 (Name: Apitegromab)[1] MSTN 💬[1] Cytokine-cytokine receptor interaction 💬[1] 3
53Apitox - pure honeybee toxin----[1] 13
54Apixaban[1] Apixaban[1] D03213 (Name: Apixaban)[1] F10 💬[1] Complement and coagulation cascades 💬[1] 222
55APL-130277----[1] 6
56APL-1401----[1] 97
57APL-2----[5] 2, 61, 62, 66, 222
58APLA12----[1] 46
59Aplindore[1] Aplindore---[1] 6
60Aplindore MR tablets[1] Aplindore---[1] 6
61APO-go----[1] 6
62APO-go®----[1] 6
63APO-P001----[1] 2
64APOKINON----[1] 6
65APOKYN[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
66Apomor----[1] 6
67Apomorfina[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
68APOMORFINA CLORIDRATO[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
69Apomorp----[1] 6
70Apomorphine[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[3] 5, 6, 7
71Apomorphine 0.25% (2.5mg/ml)[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
72Apomorphine HCl injection[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
73APOMORPHINE HYDROCHLORIDE[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
74Apomorphine hydrochloride 1.8mg inhalation powder, pre-dispensed[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
75Apomorphine hydrochloride 2.8mg inhalation powder, pre-dispensed[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
76Apomorphine hydrochloride 4.0 mg inhalation powder, pre-dispensed[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
77Apomorphine hydrochloride 5.8 mg inhalation powder, pre-dispensed[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
78APOMORPHINE HYDROCHLORIDE HEMIHYDRATE[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
79Apomorphine Hydrocloride[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
80Apomorphine Hydrocloride Hemihydrate[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
81Apomorphine infusion[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
82Apomorphine Injectable Solution[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
83Apomorphine Nasal Powder[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
84APORON----[1] 6
85ApoTamox 10mg----[1] 111
86Application of Adalimumab[1] Adalimumab[1] D02597 [1] TNF 💬[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 96
87Apply VEREGEN ® 10 % on a randomized area and the moisturizing cream of the other side[1] Sinecatechins[1] D08997 --[1] 160
88Apraclonidine[1] Apraclonidine[1] D07461 (Name: Apraclonidine)[3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 11
89Apraclonidine Hcl 0.5% Oph Soln[1] Apraclonidine[1] D07461 (Name: Apraclonidine)[3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 11
90Apratastat[1] Apratastat[1] D08859 (Name: Apratastat)[2] ADAM17,
MMP13 💬		[7] Alzheimer disease, Coronavirus disease - COVID-19, Epithelial cell signaling in Helicobacter pylori infection, IL-17 signaling pathway, Notch signaling pathway, Parathyroid hormone synthesis, secretion and action, Relaxin signaling pathway 💬[1] 46
91Apremilast[1] Apremilast[1] D08860 (Name: Apremilast)[4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[7] 46, 50, 56, 97, 107, 162, 271
92Apremilast (CC-10004)[1] Apremilast[1] D08860 (Name: Apremilast)[4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[1] 56
93Apremilast 10 mg[1] Apremilast[1] D08860 (Name: Apremilast)[4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[2] 56, 107
94Apremilast 20 mg[1] Apremilast[1] D08860 (Name: Apremilast)[4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[3] 46, 56, 107
95Apremilast 30 mg[1] Apremilast[1] D08860 (Name: Apremilast)[4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[3] 46, 56, 107
96Apremilast 30mg[1] Apremilast[1] D08860 (Name: Apremilast)[4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[1] 50
97Apremilast tablet 20 mg[1] Apremilast[1] D08860 (Name: Apremilast)[4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[1] 271
98Apremilast tablet 30 mg BID[1] Apremilast[1] D08860 (Name: Apremilast)[4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[1] 271
99APRINOX----[1] 67
100Apriso 0.375G ER CAP----[1] 97
101APRISO 375 mg extended-release capsules[1] Manganese citrate---[1] 97
102AProArt----[1] 65
103Aprotinin[1] Aprotinin[1] D02971 (Name: Aprotinin)--[1] 28
104Aprovel[1] Irbesartan (Synonym: Apo-irbesartan)[1] D00523 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 167
105Aprovel (150 mg)[1] Irbesartan (Synonym: Apo-irbesartan)[1] D00523 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 222
106Aprovel 150 mg Tablets[1] Irbesartan (Synonym: Apo-irbesartan)[1] D00523 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 222
107APT-1011----[1] 98
108APT-1011 - 3 mg----[1] 98
109APT-1011 3 mg HS----[1] 98
110APVO210----[1] 97
111Autologous apoptotic cells injection----[1] 46
112Autologous CD34+ HSCs transduced ex vivo with CD11B LV encoding human IDS tagged with ApoEII----[1] 19
113Azathioprine OR Mesalazine
(Synonym: Apriso (TN))		[2] Azathioprine (Synonym: Apo-azathioprine),
Mesalazine (Synonym: Apriso)		[2] D00238 ,
D00377 (Name: Apriso (TN))		--[1] 96
114Bosentan and Sildenafil
(Synonym: Aphrodil (TN))		[2] Bosentan (Synonym: Apo-bosentan),
Sildenafil (Synonym: Apo-sildenafil)		[3] D01227 ,
D07538 ,
D08514 (Name: Aphrodil (TN))		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
115BPR277 ointment (controlled application)----[1] 160
116Brimonidine Tartrate Posterior Segment Drug Delivery System (Brimo PS DDS) Applicator System[1] Brimonidine (Synonym: Apo-brimonidine-timop)[1] D07540 [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[1] 90
117Cabotegravir
(Synonym: APRETUDE)		[1] Cabotegravir (Synonym: Apretude)[1] D10548 (Name: APRETUDE)--[1] 256
118Cabotegravir (CAB) tablet
(Synonym: APRETUDE)		[1] Cabotegravir (Synonym: Apretude)[1] D10548 (Name: APRETUDE)--[1] 256
119Cabotegravir - Injectable Suspension (CAB LA)
(Synonym: APRETUDE)		[1] Cabotegravir (Synonym: Apretude)[1] D10548 (Name: APRETUDE)--[1] 256
120Canakinumab (WHO approval pending)[1] Canakinumab[1] D09315 [1] IL1B 💬[44] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection 💬[1] 106
121Cannabidiol Oral Solution, is known as Epidyolex 100 mg/mL oral solution and is the approved name in the EU. Epidiolex (cannabidiol) oral solution is the approved name in the US.[1] Cannabidiol[1] D10915 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 158
122Captopril
(Synonym: Apopril (TN))		[1] Captopril (Synonym: Apo-capto Tab 100mg)[1] D00251 (Name: Apopril (TN))[1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[2] 17, 86
123CBD - Oral Solution, is known as Epidiolex, and is the approved name in the USA.[1] Cannabidiol[1] D10915 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[2] 140, 144
124CBD - Oral Solution, is known as Epidyolex, and is the approved name[1] Cannabidiol[1] D10915 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 156
125CBD - Solution Orale, conosciuto come Epidiolex, questo è il nome approvato negli Stati Uniti[1] Cannabidiol[1] D10915 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 156
126CBD Oral solution, is known as Epidyolex and is the approved name in the EU[1] Cannabidiol[1] D10915 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 156
127CBD soluzione orale nota come Epidyolex e con tale nome è stato approvato in UE[1] Cannabidiol[1] D10915 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 156
128CBD-Oral Solution, is known as Epidiolex, and is the approved name in the USA.[1] Cannabidiol[1] D10915 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 158
129Continuous Apomorphine infusion[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
130Conventional treatment (glucocoticoid, immunosupressive drugs and/or mesalazine)
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[2] 96, 97
131Corticosteroids (Aprednislon)----[1] 63
132CR002 Liquid API[1] CR002---[1] 299
133Crocin and Apigenin[2] Apigenin,
Crocin		---[1] 6
134D.3.2 Product code where applicable13:----[1] 193
135Delayed and extended release mesalazine
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
136Dopaminergic Agonist + Apomorphine[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
137Duo-Therapy with Sildenafil + Bosentan
(Synonym: Aphrodil (TN))		[2] Bosentan (Synonym: Apo-bosentan),
Sildenafil (Synonym: Apo-sildenafil)		[3] D01227 ,
D07538 ,
D08514 (Name: Aphrodil (TN))		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
138EB-101 Surgical application of RDEB wounds----[1] 36
139Epidyolex and is the approved name in the EU[1] Cannabidiol[1] D10915 [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[1] 156
140ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)
(Synonym: Aphrodil (TN))		[4] Bosentan (Synonym: Apo-bosentan),
Macitentan,
Sildenafil (Synonym: Apo-sildenafil),
Tadalafil (Synonym: Apo-tadalafil)		[5] D01227 ,
D02008 ,
D07538 ,
D08514 (Name: Aphrodil (TN)),
D10135 		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
141EU-approved RoActemra[1] Tocilizumab[1] D02596 [1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 46
142EUR-1008 (APT-1008)----[1] 299
143EUR-1008 (APT-1008) High Dose----[1] 298
144EUR-1008 (APT-1008) Low Dose----[1] 298
145Ex-vivo approach concerning 25 patients----[2] 102, 299
146Firategrast (USAN approved name)[1] Firategrast[1] D06590 [1] ITGA4 💬[14] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Yersinia infection 💬[1] 13
147G04BE03- Sildenafil - sildenafil (citrato)
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
148Group 3: ustekinumab approximately 6 mg/kg[1] Ustekinumab[1] D09214 [3] IL12A,
IL12B,
IL23A 💬		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[1] 96
149Hydrokortison APL kapsel 2,5 mg----[1] 83
150In-vitro approach concerning 25 patients----[2] 102, 299
151Injection of apomorphine[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
152Interferon beta-1a (current approved manufacturing process invloving FBS)[2] Human interferon beta,
Interferon beta-1a		[1] D04554 [2] IFNAR1,
IFNAR2 💬		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[1] 13
153Investigators Choice of Approved AED----[1] 144
154Investigators choice of approved AEDs----[1] 144
155Irbesartan tablets (Approved in the USA. Reference listed drug Avapro) NDC # 43547-0374-03[1] Irbesartan (Synonym: Apo-irbesartan)[1] D00523 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 66, 222
156Irbesartan tablets (NDC# 31722-729-30 approved in the United states)[1] Irbesartan (Synonym: Apo-irbesartan)[1] D00523 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 222
157Irbesartan tablets (NDC# 43547-0374-03 and NDC 43547-374-09, approved in the USA) Generic tablets distributed by Solco Healthcare US, LLC[1] Irbesartan (Synonym: Apo-irbesartan)[1] D00523 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 222
158IV Apomorphine[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
159Kamada-API----[1] 231
160Lithium Apogepha[1] Lithium citrate[1] D04749 --[1] 2
161Locally approved intravenous contrast medium for contrast enhanced magnetic resonance imaging (MRI)----[1] 13
162Mesalazine
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[3] 46, 96, 97
163Mesalazine (3,600 mg)
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
164Mesalazine (Asacol®)
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
165Mesalazine (Mesalamine)
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 96
166Mesalazine - TID 1000 mg
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
167Mesalazine - TID 2x 500 mg
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
168Mesalazine 1000 mg gastro-resistant tablets
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
169Mesalazine 250Mg
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
170Mesalazine 250Mg Tablet and nitazoxanide 500Mg Oral Tablet
(Synonym: Apriso (TN))		[2] Mesalazine (Synonym: Apriso),
Nitazoxanide		[2] D00377 (Name: Apriso (TN)),
D02486 		--[1] 97
171Mesalazine 4G Enema
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
172Mesalazine 500 mg gastro-resistant tablets (Salofa
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
173Mesalazine 500 mg gastro-resistant tablets (Salofalk® 500 mg)
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
174Mesalazine EC 500 mg
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 96
175Mesalazine Enema
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
176Mesalazine liquid enema
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
177Mesalazine slow-release granules
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
178Mesalazine Sustained-Release Tablets
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 96
179Mesalazine tablet
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
180Mesalazine tablets
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 96
181Mesalazine with hydrocortisone sodium succinate
(Synonym: Apriso (TN))		[2] Hydrocortisone (Synonym: Apres Peel Soothing Balm),
Mesalazine (Synonym: Apriso)		[2] D00088 ,
D00377 (Name: Apriso (TN))		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
182Mesalazine, Tripterygium glycosides
(Synonym: Apriso (TN))		[2] Mesalazine (Synonym: Apriso),
Tripterygium wilfordii whole		[1] D00377 (Name: Apriso (TN))--[1] 96
183MMX mesalamine/ mesalazine
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
184MMX Mesalamine/Mesalazine
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
185MMX Mesalamine/Mesalazine (High Dose)
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
186MMX Mesalamine/Mesalazine (Low Dose)
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
187Mono-Therapy with Sildenafil
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
188Non applicabile----[4] 13, 49, 51, 256
189Non applicable----[2] 10, 19
190Oral sildenafil
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
191Overencapsulated mesalazine tablets
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
192Part 1 Levulan surface application----[1] 34
193Part 1 Levulan surface application twice----[1] 34
194Part 1 Levulan surface application twice with microneedling----[1] 34
195Patients' existing non-steroidal anti-inflammatory drug (NSAID) at approved doses----[1] 46
196Pegcetacoplan (APL-2)[1] Pegcetacoplan[1] D11613 [1] C3 💬[17] Alcoholic liver disease, Chagas disease, Complement and coagulation cascades, Coronavirus disease - COVID-19, Herpes simplex virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Phagosome, Shigellosis, Staphylococcus aureus infection, Systemic lupus erythematosus, Tuberculosis, Viral carcinogenesis 💬[3] 2, 61, 62
197Pharmacologic approaches to glycemic treatment----[1] 298
198Primary Cervical Dystonia (Trihexyphenidyl)
(Synonym: Apo-trihex (TN))		[1] Trihexyphenidyl (Synonym: Aparkane Tab 2mg)[1] D08638 (Name: Apo-trihex (TN))[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 6
199Recombinant Human Angiotensin-converting enzyme 2 (ACE2), APN01[2] Alunacedase alfa,
Angiotensin II		[2] D00150 ,
D02014 		[2] AGTR1,
AGTR2 💬		[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86
200Recombinant Human Apolipoprotein----[1] 79
201Recombinant Human Apolipoprotein A-I----[1] 79
202Recombinant Human Apolipoprotein A-I/Phospholipids Complex[1] Omega-3 fatty acids---[1] 79
203Recombinant human apolipoprotein a1----[1] 79
204Riociguat granules 0.3% for oral application[1] Riociguat[1] D09572 [3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬		[11] Circadian entrainment, Gap junction, Long-term depression, Metabolic pathways, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 86
205S.c. apomorphine[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
206Sildenafil
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301
207Sildenafil (50 mg)
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 85
208Sildenafil (Acute-1 hour)
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 299
209Sildenafil (as citrate)
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
210Sildenafil (REVATIO)
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
211Sildenafil (Revatio) 20 mg TID
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
212Sildenafil (Subchronic-4 weeks)
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 299
213Sildenafil 20 mg tablets
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 278
214Sildenafil 20mg
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[2] 51, 86
215Sildenafil 20mg and Bosentan 62.5mg
(Synonym: Aphrodil (TN))		[2] Bosentan (Synonym: Apo-bosentan),
Sildenafil (Synonym: Apo-sildenafil)		[3] D01227 ,
D07538 ,
D08514 (Name: Aphrodil (TN))		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 51, 86
216Sildenafil 40mg oral capsule
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 299
217Sildenafil and Losartan
(Synonym: Aphrodil (TN))		[2] Losartan (Synonym: Apo-losartan/hctz),
Sildenafil (Synonym: Apo-sildenafil)		[2] D08146 ,
D08514 (Name: Aphrodil (TN))		[2] AGTR1,
PDE5A 💬		[18] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Purine metabolism, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 85
218Sildenafil by injection
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 210
219Sildenafil citrate
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[4] 51, 85, 86, 225
220Sildenafil citrate (UK-92,480)
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
221Sildenafil Filmtabletten
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
222Sildenafil Oral Suspension
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 294
223Sildenafil singly or in association with Bosentan
(Synonym: Aphrodil (TN))		[2] Bosentan (Synonym: Apo-bosentan),
Sildenafil (Synonym: Apo-sildenafil)		[3] D01227 ,
D07538 ,
D08514 (Name: Aphrodil (TN))		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
224Sildenafil therapy
(Synonym: Aphrodil (TN))		[1] Sildenafil (Synonym: Apo-sildenafil)[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 51
225Sitaxsentan and Sildenafil
(Synonym: Aphrodil (TN))		[2] Sildenafil (Synonym: Apo-sildenafil),
Sitaxentan		[2] D07171 ,
D08514 (Name: Aphrodil (TN))		[2] EDNRA,
PDE5A 💬		[9] Calcium signaling pathway, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
226Sodium tanshinone IIA sulfonate diluted with 5% glucose solution,20mg sildenafil citrate by mouth
(Synonym: Aphrodil (TN))		[2] Dextrose, unspecified form,
Sildenafil (Synonym: Apo-sildenafil)		[1] D08514 (Name: Aphrodil (TN))[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 86
227SPD476 (mesalazine)
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
228SPD476 is a polymeric matrix formulation that displays both delayed- and extended-release of mesalazine
(Synonym: Apriso (TN))		[1] Mesalazine (Synonym: Apriso)[1] D00377 (Name: Apriso (TN))--[1] 97
229Spironolactone captopril carvedilol
(Synonym: Apopril (TN))		[3] Captopril (Synonym: Apo-capto Tab 100mg),
Carvedilol (Synonym: Apo-carvedilol),
Spironolactone (Synonym: Apo-spirozide Tab)		[3] D00251 (Name: Apopril (TN)),
D00255 ,
D00443 		[7] ACE,
ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
ADRB2,
NR3C2 💬		[19] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone-regulated sodium reabsorption, Calcium signaling pathway, Chagas disease, Chemical carcinogenesis - receptor activation, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dilated cardiomyopathy, Gap junction, Hypertrophic cardiomyopathy, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Renin-angiotensin system, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
230Subcutaneous apomorphine[1] Apomorphine[1] D07460 (Name: Apomorphine)[2] DRD1,
DRD2 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
231Tadalafil and Sildenafil
(Synonym: Aphrodil (TN))		[2] Sildenafil (Synonym: Apo-sildenafil),
Tadalafil (Synonym: Apo-tadalafil)		[2] D02008 ,
D08514 (Name: Aphrodil (TN))		[1] PDE5A 💬[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway 💬[1] 113
232Tezepelumab via APFS[1] Tezepelumab[1] D11771 [1] TSLP 💬[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[1] 98
233Tipranavir
(Synonym: Aptivus (TN))		[1] Tipranavir (Synonym: Aptivus)[1] D08605 (Name: Aptivus (TN))--[1] 265
234Trifluoperazine
(Synonym: Apo-trifluoperazine (TN))		[1] Trifluoperazine[2] D01448 ,
D08636 (Name: Apo-trifluoperazine (TN))		[1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 283, 284
235Trihexyphenidyl
(Synonym: Apo-trihex (TN))		[1] Trihexyphenidyl (Synonym: Aparkane Tab 2mg)[1] D08638 (Name: Apo-trihex (TN))[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 5, 6
236Ustekinumab (approximately 6 mg/kg)[1] Ustekinumab[1] D09214 [3] IL12A,
IL12B,
IL23A 💬		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[1] 49
237Ustekinumab approximately 6 mg/kg (IV)[1] Ustekinumab[1] D09214 [3] IL12A,
IL12B,
IL23A 💬		[28] African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus 💬[1] 96
238VOLANESORSEN SODIUM, ApoC-III Antisense Oligonucleotide[1] Volanesorsen[1] D11648 [1] APOC3 💬[2] Cholesterol metabolism, PPAR signaling pathway 💬[1] 265