Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Bosentan[1] Bosentan[2] D01227 (Name: Bosentan),
D07538 (Name: Bosentan)		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
2Bosentan (Tracleer)[1] Bosentan[2] D01227 (Name: Bosentan),
D07538 (Name: Bosentan)		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51
3Bosentan 125 mg[1] Bosentan[2] D01227 (Name: Bosentan),
D07538 (Name: Bosentan)		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51
4Bosentan 62.5 mg[1] Bosentan[2] D01227 (Name: Bosentan),
D07538 (Name: Bosentan)		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51
5Bosentan administration[1] Bosentan[2] D01227 (Name: Bosentan),
D07538 (Name: Bosentan)		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
6Bosentan and Sildenafil[2] Bosentan,
Sildenafil		[3] D01227 (Name: Bosentan),
D07538 (Name: Bosentan),
D08514 		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
7Bosentan group[1] Bosentan[2] D01227 (Name: Bosentan),
D07538 (Name: Bosentan)		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51
8BOSENTAN MONOHIDRATO[1] Bosentan[2] D01227 (Name: Bosentan),
D07538 (Name: Bosentan)		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
9Bosentan monohydrat[1] Bosentan[2] D01227 (Name: Bosentan),
D07538 (Name: Bosentan)		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
10BOSENTAN MONOHYDRATE[1] Bosentan[2] D01227 (Name: Bosentan),
D07538 (Name: Bosentan)		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 51, 84, 86, 88
11BOSENTAN MYLAN[1] Bosentan[2] D01227 (Name: Bosentan),
D07538 (Name: Bosentan)		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 41
12Bosentan, Ambrisentan[2] Ambrisentan,
Bosentan		[3] D01227 (Name: Bosentan),
D07077 ,
D07538 (Name: Bosentan)		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
13Duo-Therapy with Sildenafil + Bosentan[2] Bosentan,
Sildenafil		[3] D01227 (Name: Bosentan),
D07538 (Name: Bosentan),
D08514 		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
14ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)[4] Bosentan,
Macitentan,
Sildenafil,
Tadalafil		[5] D01227 (Name: Bosentan),
D02008 ,
D07538 (Name: Bosentan),
D08514 ,
D10135 		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
15Sildenafil 20mg and Bosentan 62.5mg[2] Bosentan,
Sildenafil		[3] D01227 (Name: Bosentan),
D07538 (Name: Bosentan),
D08514 		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 51, 86
16Sildenafil singly or in association with Bosentan[2] Bosentan,
Sildenafil		[3] D01227 (Name: Bosentan),
D07538 (Name: Bosentan),
D08514 		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86