Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Conventional Glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone)[7] Acetate,
Cortisone,
Cortisone acetate,
Dexamethasone,
Hydrocortisone,
Prednisolone,
Prednisone		[6] D00088 ,
D00292 ,
D00472 ,
D00473 ,
D00973 ,
D07749 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 81
2Cyclophosphamide followed by methotrexate (azathioprine) + glucocorticoids or methotrexate (azathioprine) + glucocorticoids[3] Azathioprine,
Cyclophosphamide,
Methotrexate		[4] D00142 ,
D00238 ,
D00287 ,
D07760 		[2] DHFR,
DHFR2 💬		[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate 💬[1] 44
3Cyclosporin A+Glucocorticoids[1] Cyclosporine[1] D00184 [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[2] 60, 62
4GlucoCorticoid----[2] 46, 228
5Glucocorticoid (GC)----[2] 43, 44
6Glucocorticoid (prednisone or prednisolone)[2] Prednisolone,
Prednisone		[2] D00472 ,
D00473 		[1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 84
7Glucocorticoid + cytoxan----[1] 222
8Glucocorticoid + tacrolimus[1] Tacrolimus[2] D00107 ,
D08556 		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[1] 222
9Glucocorticoid Agent----[1] 46
10Glucocorticoid combined with cyclophosphamide induction + maintenance[1] Cyclophosphamide[2] D00287 ,
D07760 		--[1] 222
11Glucocorticoid Treatment----[1] 41
12Glucocorticoids----[8] 40, 41, 43, 44, 60, 62, 75, 300
13Glucocorticoids (GC)----[2] 43, 44
14Glucocorticoids (permitted,not necessary)----[1] 46
15Glucocorticoids - Reduced Dose----[2] 43, 44
16Glucocorticoids - Standard Dose----[2] 43, 44
17Glucocorticoids [Reduced Dose]----[2] 43, 44
18Glucocorticoids [Standard Dose]----[2] 43, 44
19Gusperimus + glucocorticoids[1] Gusperimus[1] D08032 --[1] 44
20Levamisole+cyclosporin A+Glucocorticoids[2] Cyclosporine,
Levamisole		[2] D00184 ,
D08114 		[5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[2] 60, 62
21Methylprednisolone (or other glucocorticoid)[1] Methylprednisolone[1] D00407 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 43
22Standard glucocorticoid therapy----[1] 81
23Tocilizumab + Glucocorticoids (GCs)[1] Tocilizumab[1] D02596 [1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[1] 41
24Ursodeoxycholic acid+Low Dose Glucocorticoid(Methylprednisolone)[2] Methylprednisolone,
Ursodeoxycholic acid		[2] D00407 ,
D00734 		[2] NR1H4,
NR3C1 💬		[2] Bile secretion, Neuroactive ligand-receptor interaction 💬[1] 93