Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Acthar high dose (80 U)[1] Corticotropin[1] D00146 [1] MC2R 💬[5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 49
2Administration of a high dose of desipramine[1] Desipramine[1] D07791 [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[1] 156
3Ambrisentan - high dose[1] Ambrisentan[1] D07077 [1] EDNRA 💬[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
4AXO-AAV-GM2 High Dose----[1] 19
5BI 655064 high dose----[1] 46
6BIIL 284 BS high dose----[1] 46
7BIIL 284 BS, high dose----[1] 299
8BIIL 284 BS, high dose, adult patients----[1] 299
9BIIL 284 BS, high dose, pediatric patients----[1] 299
10BIRB 796 BS, high dose----[1] 46
11BLI-1300 high dose----[1] 96
12Brazikumab high dose[1] Brazikumab[1] D10912 [1] IL23A 💬[9] C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬[1] 96
13CHF10067 high dose----[1] 85
14Clobazam High Dose[1] Clobazam[1] D01253 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 144
15CPL500036 - high dose----[1] 6
16CVT-301 High Dose----[1] 6
17DNS-7801 (high dose)----[1] 6
18Elamipretide (high dose)[1] Elamipretide[1] D10925 --[1] 21
19Enpatoran high dose----[1] 49
20EUR-1008 (APT-1008) High Dose----[1] 298
21Fentanyl (High Dose)[1] Fentanyl[1] D00320 [1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 215
22GTX-102 high dose fast Period 1 and Period 2[1] GTX-102---[1] 65
23High dose----[1] 97
24High dose AFFITOPE® PD03A + Adjuvant----[1] 6
25High dose ANAVEX2-73----[1] 6
26High Dose Aspirin (1300 mg/day)[1] Acetylsalicylic acid[1] D00109 [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 13
27High dose BIBF 1120 twice daily----[1] 85
28High Dose Budesonide[1] Budesonide[1] D00246 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 97
29High dose budesonide suspension[1] Budesonide[1] D00246 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 98
30High dose budesonide tablet[1] Budesonide[1] D00246 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 98
31High dose Dexamethasone pulses[1] Dexamethasone[1] D00292 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 63
32High dose lactulose[1] Lactulose[1] D00352 --[1] 291
33High dose levodopa[1] Levodopa[1] D00059 [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
34High Dose LX2006----[1] 18
35High Dose Mesenchymal Stem Cells (MSCs)----[1] 49
36High Dose MT-1303----[1] 97
37High Dose MYOBLOC[1] Botulinum toxin type B[1] D02735 [1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[1] 13
38High dose of BIIL 284 BS tablets----[1] 46
39High dose of budesonide[1] Budesonide[1] D00246 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 299
40High dose ORTD-1----[1] 46
41High dose TSO----[1] 96
42High dose vehicle control----[1] 46
43High Dose-VIS649----[1] 66
44High doses of Thiamine y Biotin[2] Biotin,
Thiamine		[2] D00029 ,
D08580 		--[1] 8
45HMPL-004 high dose----[1] 97
46IgPro20 (high dose)----[1] 14
47Imsidolimab high dose[1] Imsidolimab[1] D11892 [1] IL1RL2 💬[1] Cytokine-cytokine receptor interaction 💬[1] 37
48KPS-0373, High dose----[1] 18
49KW-6356 High Dose[1] KW-6356---[1] 6
50LiRIS low dose and LiRIS high dose----[1] 226
51LX3305 high dose----[1] 46
52M5049 high dose----[2] 49, 50
53MEDI7183 high dose----[1] 97
54MMX Mesalamine/Mesalazine (High Dose)[1] Mesalazine[1] D00377 --[1] 97
55MT-1303 High dose----[1] 49
56MT-7117 High Dose----[1] 254
57MultiStem high dose[1] MultiStem---[1] 97
58OCU400 High Dose----[1] 90
59Orelabrutinib (High Dose)[1] Orelabrutinib[1] D12160 [1] BTK 💬[7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[1] 49
60Part 2 Adult Alogabat High Dose (aged 15-17)----[1] 201
61PF-06649751 high dose (15 mg QD)[1] Tavapadon[1] D11431 [2] DRD1,
DRD5 💬		[10] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬[1] 6
62PHA-022121 high dose----[1] 65
63PXT3003 High Dose----[1] 10
64Ravicti high dose[1] Glycerol phenylbutyrate[1] D10127 --[1] 299
65SA001 High dose----[1] 53
66SC0062 high dose----[1] 66
67SEN0014196 (High Dose)----[1] 8
68TAS5315 high dose----[1] 46
69Vitamin D3 - high dose[1] Cholecalciferol[1] D00188 [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[1] 6
70YRA-1909 high dose----[1] 46