Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Experimental: Seladelpar / MBX-8025 200 mg[1] Seladelpar[1] D11256 [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[1] 93
2Experimental: Seladelpar / MBX-8025 50 mg[1] Seladelpar[1] D11256 [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[1] 93
3MBX-8025----[3] 79, 93, 94
4MBX-8025 50 mg (Dose Escalation Period 1)----[1] 79
5MBX-8025 50 mg or 100 mg (Dose Escalation Period 2)----[1] 79
6MBX-8025 50 mg, 100 mg or 200 mg (Dose Escalation Period 3)----[1] 79
7MBX-8025, DSIC----[1] 93
8MBX-8025, Formulation 2----[1] 93