Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Bosentan
(Synonym: Tracleer (TN))		[1] Bosentan (Synonym: Tracleer)[2] D01227 (Name: Tracleer (TN)),
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[10] 41, 47, 51, 84, 85, 86, 88, 210, 211, 212
2Bosentan (Tracleer)[1] Bosentan (Synonym: Tracleer)[2] D01227 (Name: Tracleer (TN)),
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51
3Bosentan 125 mg
(Synonym: Tracleer (TN))		[1] Bosentan (Synonym: Tracleer)[2] D01227 (Name: Tracleer (TN)),
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51
4Bosentan 62.5 mg
(Synonym: Tracleer (TN))		[1] Bosentan (Synonym: Tracleer)[2] D01227 (Name: Tracleer (TN)),
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51
5Bosentan administration
(Synonym: Tracleer (TN))		[1] Bosentan (Synonym: Tracleer)[2] D01227 (Name: Tracleer (TN)),
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
6Bosentan and Sildenafil
(Synonym: Tracleer (TN))		[2] Bosentan (Synonym: Tracleer),
Sildenafil		[3] D01227 (Name: Tracleer (TN)),
D07538 ,
D08514 		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
7Bosentan group
(Synonym: Tracleer (TN))		[1] Bosentan (Synonym: Tracleer)[2] D01227 (Name: Tracleer (TN)),
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 51
8BOSENTAN MONOHIDRATO
(Synonym: Tracleer (TN))		[1] Bosentan (Synonym: Tracleer)[2] D01227 (Name: Tracleer (TN)),
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
9Bosentan monohydrat
(Synonym: Tracleer (TN))		[1] Bosentan (Synonym: Tracleer)[2] D01227 (Name: Tracleer (TN)),
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
10BOSENTAN MONOHYDRATE
(Synonym: Tracleer (TN))		[1] Bosentan (Synonym: Tracleer)[2] D01227 (Name: Tracleer (TN)),
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 51, 84, 86, 88
11BOSENTAN MYLAN
(Synonym: Tracleer (TN))		[1] Bosentan (Synonym: Tracleer)[2] D01227 (Name: Tracleer (TN)),
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 41
12Bosentan, Ambrisentan
(Synonym: Tracleer (TN))		[2] Ambrisentan,
Bosentan (Synonym: Tracleer)		[3] D01227 (Name: Tracleer (TN)),
D07077 ,
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
13Duo-Therapy with Sildenafil + Bosentan
(Synonym: Tracleer (TN))		[2] Bosentan (Synonym: Tracleer),
Sildenafil		[3] D01227 (Name: Tracleer (TN)),
D07538 ,
D08514 		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
14ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)
(Synonym: Tracleer (TN))		[4] Bosentan (Synonym: Tracleer),
Macitentan,
Sildenafil,
Tadalafil		[5] D01227 (Name: Tracleer (TN)),
D02008 ,
D07538 ,
D08514 ,
D10135 		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
15Observational study with patients treated with Tracleer, Ventavis, Veletri, Opsumit and/or Uptravi[4] Epoprostenol,
Iloprost,
Macitentan,
Selexipag		[4] D00106 ,
D02721 ,
D09994 ,
D10135 		[3] EDNRA,
EDNRB,
PTGIR 💬		[10] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Platelet activation, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
16Sildenafil 20mg and Bosentan 62.5mg
(Synonym: Tracleer (TN))		[2] Bosentan (Synonym: Tracleer),
Sildenafil		[3] D01227 (Name: Tracleer (TN)),
D07538 ,
D08514 		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 51, 86
17Sildenafil singly or in association with Bosentan
(Synonym: Tracleer (TN))		[2] Bosentan (Synonym: Tracleer),
Sildenafil		[3] D01227 (Name: Tracleer (TN)),
D07538 ,
D08514 		[3] EDNRA,
EDNRB,
PDE5A 💬		[11] Calcium signaling pathway, Melanogenesis, Metabolic pathways, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
18Tracleer[1] Bosentan (Synonym: Tracleer)[2] D01227 (Name: Tracleer (TN)),
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[8] 13, 51, 84, 85, 86, 88, 210, 211
19TRACLEER 125MG 56CPR RIV.[1] Bosentan (Synonym: Tracleer)[2] D01227 (Name: Tracleer (TN)),
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 88
20TRACLEER 62,5 mg comprimidos recubiertos con película[1] Bosentan (Synonym: Tracleer)[2] D01227 (Name: Tracleer (TN)),
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
21TRACLEER 62,5MG 56CPR RIV.[1] Bosentan (Synonym: Tracleer)[2] D01227 (Name: Tracleer (TN)),
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
22TRACLEER*125MG 56CPR RIV.[1] Bosentan (Synonym: Tracleer)[2] D01227 (Name: Tracleer (TN)),
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 51, 86
23TRACLEER*56CPR RIV 125MG[1] Bosentan (Synonym: Tracleer)[2] D01227 (Name: Tracleer (TN)),
D07538 		[2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 86, 88
24Tracleer®----[1] 86