Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Ivacaftor+lumacaftor
(D10134)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor ,
Lumacaftor (D10134) 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
2LUMACAFTOR
(D10134)		[1] Lumacaftor[1] Lumacaftor (D10134) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
3Lumacaftor / ivacaftor
(D10134)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor ,
Lumacaftor (D10134) 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
4Lumacaftor plus Ivacaftor
(D10134)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor ,
Lumacaftor (D10134) 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
5Lumacaftor Plus Ivacaftor Combination
(D10134)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor ,
Lumacaftor (D10134) 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
6Lumacaftor, Ivacaftor Drug Combination
(D10134)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor ,
Lumacaftor (D10134) 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
7Lumacaftor-ivacaftor
(D10134)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor ,
Lumacaftor (D10134) 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
8Lumacaftor-Ivacaftor treatment
(D10134)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor ,
Lumacaftor (D10134) 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
9Lumacaftor/Ivacaftor
(D10134)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor ,
Lumacaftor (D10134) 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
10Lumacaftor/ivacaftor 100mg/125mg tablets
(D10134)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor ,
Lumacaftor (D10134) 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
11Lumacaftor/ivacaftor 200mg/125mg
(D10134)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor ,
Lumacaftor (D10134) 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
12Lumacaftor/ivacaftor 200mg/125mg tablets
(D10134)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor ,
Lumacaftor (D10134) 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
13Lumacaftor/ivacaftor 200mg/83mg tablet
(D10134)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor ,
Lumacaftor (D10134) 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
14Orkambi: contains lumacaftor and ivacaftor
(D10134)		[2] Ivacaftor,
Lumacaftor		[2] Ivacaftor ,
Lumacaftor (D10134) 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
15Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor
(D10134)		[4] Elexacaftor,
Ivacaftor,
Lumacaftor,
Tezacaftor		[4] Ivacaftor ,
Lumacaftor (D10134),
Tezacaftor ,
Elexacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬