Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Obeticholic acid 💬[1] Obeticholic acid[4] 6-ECDCA; 6-ethylchenodeoxycholic acid; OBETICHOLIC ACID; Ocaliva[1] NR1H4 💬 [1] Bile secretion 💬[3] 93, 265, 296 💬
2 Obexelimab 💬[1] Obexelimab[1] Obexelimab[1] CD19 💬 [5] B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬[1] 300 💬
3 Obinutuzumab 💬[1] Obinutuzumab[2] GAZYVARO; Obinutuzumab[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[4] 43, 44, 49, 222 💬
4 Ocrelizumab 💬[1] Ocrelizumab[3] Ocrelizumab; OCREVUS; RhuMAb 2H7[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[3] 13, 46, 49 💬
5 Octreotide 💬[1] Octreotide[3] Octreotide; OCTREOTIDE ACETATE; Sandostatin LAR[1] SSTR2 💬 [4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[7] 67, 75, 84, 85, 89, 193, 227 💬
6 Odevixibat 💬[1] Odevixibat[1] Odevixibat[1] SLC10A2 💬 [1] Bile secretion 💬[3] 296, 297, 338 💬
7 Ofatumumab 💬[1] Ofatumumab[4] Arzerra; HuMax-CD20; Kesimpta; Ofatumumab[1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[3] 13, 35, 46 💬
8 Olanzapine 💬[1] Olanzapine[2] Olanzapine; Zyprexa[11] ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2A,
HTR2B,
HTR2C,
HTR6 💬 		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 2, 8 💬
9 Olaparib 💬[1] Olaparib[1] Olaparib[2] PARP1,
PARP2 💬 		[5] Apoptosis, Base excision repair, Diabetic cardiomyopathy, NF-kappa B signaling pathway, Necroptosis 💬[2] 86, 285 💬
10 Oleic acid 💬[1] Oleic Acid[1] Oleic Acid--[2] 13, 299 💬
11 Olesoxime 💬[1] Olesoxime[1] OLESOXIME--[3] 2, 3, 13 💬
12 Olipudase alfa 💬[1] Olipudase alfa[1] OLIPUDASE ALFA[1] SMPD1 💬 [5] Lysosome, Metabolic pathways, Necroptosis, Sphingolipid metabolism, Sphingolipid signaling pathway 💬[1] 19 💬
13 Olive oil 💬[1] Olive oil[1] Olive Oil--[5] 13, 35, 49, 53, 162 💬
14 Olokizumab 💬[1] Olokizumab[1] Olokizumab[1] IL6 💬 [51] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection 💬[2] 46, 96 💬
15 Olsalazine 💬[1] Olsalazine[1] Olsalazine--[1] 271 💬
16 Omadacycline 💬[1] Omadacycline[1] Omadacycline--[1] 299 💬
17 Omalizumab 💬[1] Omalizumab[2] Omalizumab; XOLAIR[1] FCER1A 💬 [4] Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬[7] 46, 53, 65, 98, 162, 226, 299 💬
18 Omaveloxolone 💬[1] Omaveloxolone[1] Omaveloxolone[1] NFE2L2 💬 [7] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬[1] 18 💬
19 Omeprazole 💬[1] Omeprazole[4] Losec; Omeprazol; Omeprazole; OMEPRAZOLE MAGNESIUM[2] ATP4A,
ATP4B 💬 		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[14] 6, 8, 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
20 Onasemnogene abeparvovec 💬[1] Onasemnogene abeparvovec[3] ONASEMNOGENE ABEPARVOVEC; Onasemnogene Abeparvovec-xioi; Zolgensma[1] SMN1 💬 [1] 💬[1] 3 💬
21 Ondansetron 💬[1] Ondansetron[1] Ondansetron[5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬 		[2] Serotonergic synapse, Taste transduction 💬[3] 6, 97, 107 💬
22 Opicapone 💬[1] Opicapone[2] Ongentys; OPICAPONE[1] COMT 💬 [4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[1] 6 💬
23 Opicinumab 💬[1] Opicinumab[1] Opicinumab[1] LINGO1 💬 [1] 💬[1] 13 💬
24 Oprelvekin 💬[1] Oprelvekin[5] IL-11; Interleukin 11; Interleukin-11; Oprelvekin; Recombinant interleukin-11[1] IL11RA 💬 [3] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬[2] 96, 288 💬
25 Orelabrutinib 💬[1] Orelabrutinib[1] Orelabrutinib[1] BTK 💬 [7] B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬[4] 13, 49, 61, 63 💬
26 Orilanolimab 💬[1] Orilanolimab[1] ORILANOLIMAB[1] FCGRT 💬 [1] 💬[1] 61 💬
27 Ornithine 💬[1] Ornithine[1] Ornithine--[2] 245, 251 💬
28 Orvepitant 💬[1] Orvepitant[1] ORVEPITANT[1] TACR1 💬 [2] Calcium signaling pathway, Neuroactive ligand-receptor interaction 💬[1] 85 💬
29 Oseltamivir 💬[1] Oseltamivir[1] Oseltamivir--[2] 97, 299 💬
30 Osilodrostat 💬[1] Osilodrostat[1] OSILODROSTAT[1] CYP11B2 💬 [3] Aldosterone synthesis and secretion, Metabolic pathways, Steroid hormone biosynthesis 💬[1] 75 💬
31 Otelixizumab 💬[1] Otelixizumab[1] Otelixizumab[3] CD3D,
CD3E,
CD3G 💬 		[11] Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[1] 46 💬
32 Otilimab 💬[1] Otilimab[1] OTILIMAB[1] CSF2 💬 [16] Acute myeloid leukemia, Amoebiasis, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, IL-17 signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Natural killer cell mediated cytotoxicity, Rheumatoid arthritis, Shigellosis, T cell receptor signaling pathway, TNF signaling pathway, Transcriptional misregulation in cancer 💬[1] 46 💬
33 Oxandrolone 💬[1] Oxandrolone[1] Oxandrolone[1] AR 💬 [4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[2] 211, 285 💬
34 Oxatomide 💬[1] Oxatomide[1] Oxatomide[1] ALOX5 💬 [6] Arachidonic acid metabolism, Fc epsilon RI signaling pathway, Metabolic pathways, Ovarian steroidogenesis, Serotonergic synapse, Toxoplasmosis 💬[1] 113 💬
35 Oxcarbazepine 💬[1] Oxcarbazepine[2] Oxcarbazepine; Trileptal[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 13 💬
36 Oxiconazole 💬[1] Oxiconazole[1] Oxiconazole--[1] 160 💬
37 Oxiglutatione 💬[1] Glutathione[2] Glutathione; Reduced Glutathione--[2] 6, 299 💬
38 Oxybuprocaine 💬[1] Oxybuprocaine[1] Oxybuprocaine[5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[1] 6 💬
39 Oxybutynin 💬[1] Oxybutynin[1] Oxybutynin[5] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		[13] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[3] 6, 13, 53 💬
40 Oxycodone 💬[1] Oxycodone[2] Oxycodone; OXYCODONE HYDROCHLORIDE[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[5] 6, 13, 70, 226, 298 💬
41 Oxygen 💬[1] Oxygen[3] Medical air; Nitrogen; Oxygen--[13] 6, 49, 70, 85, 86, 88, 90, 96, 168, 193, 271, 299, 330 💬
42 Oxymorphone 💬[1] Oxymorphone[1] Opana[1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 70 💬
43 Oxyquinoline 💬[1] Oxyquinoline[1] Oxine--[1] 13 💬
44 Oxytocin 💬[1] Oxytocin[2] Oxytocin; Syntocinon[1] OXTR 💬 [4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[7] 6, 72, 127, 168, 193, 206, 226 💬
45 Ozanezumab 💬[1] Ozanezumab[1] Ozanezumab[1] RTN4 💬 [1] Alzheimer disease 💬[1] 2 💬
46 Ozanimod 💬[1] Ozanimod[2] Ozanimod; Zeposia[5] S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬 		[3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬[3] 13, 96, 97 💬
47 Ozoralizumab 💬[1] Ozoralizumab[1] Ozoralizumab[1] TNF 💬 [67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[1] 46 💬