1. Spinal and bulbar muscular atrophy Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 18 / Drugs : 15 - (DrugBank : 8) / Drug target genes : 10 - Drug target pathways : 17
Spinal and bulbar muscular atrophy and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 1 | Spinal and bulbar muscular atrophy | - |
| 2 | Amyotrophic lateral sclerosis | 10.000 |
| 46 | Malignant rheumatoid arthritis | 6.469 |
| 113 | Muscular dystrophy | 5.149 |
| 86 | Pulmonary arterial hypertension | 5.047 |
| 96 | Crohn disease | 4.987 |
| 6 | Parkinson disease | 4.978 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 4.955 |
| 256 | Muscle glycogenosis | 4.065 |
| 231 | Alpha-1-antitrypsin deficiency | 4.011 |
| 168 | Ehlers-Danlos syndrome | 3.889 |
| 53 | Sjogren syndrome | 3.862 |
| 70 | Spinal stenosis | 3.818 |
| 51 | Scleroderma | 3.727 |
| 10 | Charcot-Marie-Tooth disease | 3.636 |
| 38 | Stevens-Johnson syndrome | 3.333 |
| 114 | Non-dystrophic myotonia syndrome | 3.194 |
| 127 | Frontotemporal lobar degeneration | 2.812 |
| 58 | Hypertrophic cardiomyopathy | 2.760 |
| 140 | Dorabe syndrome | 2.760 |
| 36 | Epidermolysis bullosa | 2.755 |
| 144 | Lennox-Gastaut syndrome | 2.755 |
| 193 | Prader-Willi syndrome | 2.745 |
| 107 | Juvenile idiopathic arthritis | 2.740 |
| 298 | Hereditary pancreatitis | 2.736 |
| 226 | Interstitial cystitis with Hunners ulcer | 2.695 |
| 28 | Systemic amyloidosis | 2.689 |
| 156 | Rett syndrome | 2.662 |
| 84 | Sarcoidosis | 2.652 |
| 8 | Huntington disease | 2.649 |
| 34 | Neurofibromatosis | 2.644 |
| 97 | Ulcerative colitis | 2.587 |
| 3 | Spinal muscular atrophy | 1.019 |
| 111 | Congenital myopathy | 1.000 |