DR info

Clinical trials : 447 / Drugs : 297 - (DrugBank : 57) / Drug target genes : 52 - Drug target pathways : 146

Juvenile idiopathic arthritis and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
107	Juvenile idiopathic arthritis	-
46	Malignant rheumatoid arthritis	42.012
13	Multiple sclerosis/Neuromyelitis optica	33.664
97	Ulcerative colitis	33.351
96	Crohn disease	27.297
50	Dermatomyositis	22.615
271	Ankylosing spondylitis	21.244
51	Scleroderma	20.677
6	Parkinson disease	20.545
65	Primary immunodeficiency	20.306
53	Sjogren syndrome	17.920
2	Amyotrophic lateral sclerosis	17.181
84	Sarcoidosis	17.122
49	Systemic lupus erythematosus	17.094
113	Muscular dystrophy	15.173
41	Giant cell arteritis	15.152
56	Behcet disease	14.530
11	Myasthenia gravis	14.323
226	Interstitial cystitis with Hunners ulcer	13.671
162	Pemphigoid	12.650
38	Stevens-Johnson syndrome	11.700
40	Takayasu arteritis	10.731
55	Relapsing polychondritis	10.277
299	Cystic fibrosis	10.256
222	Primary nephrotic syndrome	9.704
60	Aplastic anemia	9.143
269	Pyogenic arthritis	8.687
58	Hypertrophic cardiomyopathy	8.615
28	Systemic amyloidosis	8.505
19	Lysosomal storage disease	8.377
228	Bronchiolitis obliterans	8.110
93	Primary biliary cholangitis	7.862
284	Diamond-Blackfan anemia	7.804
256	Muscle glycogenosis	7.339
224	Purpura nephritis	7.308
164	Oculocutaneous albinism	6.978
34	Neurofibromatosis	6.960
285	Fanconi anemia	6.462
286	Hereditary sideroblastic anemia	6.243
95	Autoimmune hepatitis	6.174
39	Toxic epidermal necrolysis	6.154
270	Chronic recurrent multifocal osteomyelitis	6.000
151	Rasmussen encephalitis	6.000
231	Alpha-1-antitrypsin deficiency	5.934
66	IgA nephropathy	5.934
86	Pulmonary arterial hypertension	5.928
44	Wegener granulomatosis	5.769
298	Hereditary pancreatitis	5.642
8	Huntington disease	5.474
45	Eosinophilic granulomatosis with Polyangiitis	5.279
160	Congenital ichthyosis	5.279
283	Acquired pure red cell aplasia	5.279
63	Idiopathic thrombocytopenic purpura	5.231
36	Epidermolysis bullosa	5.030
42	Polyarteritis nodosa	5.030
302	Leber hereditary optic neuropathy	5.000
300	IgG4-related disease	4.841
326	Osteopetrosis	4.615
85	Idiopathic interstitial pneumonia	4.530
78	Hypopituitarism	4.495
70	Spinal stenosis	4.448
21	Mitochondrial disease	4.357
168	Ehlers-Danlos syndrome	4.231
106	Cryopyrin-associated periodic syndrome	4.000
274	Osteogenesis Imperfecta	3.971
62	Paroxysmal nocturnal hemoglobinuria	3.810
35	Pemphigus	3.692
323	Aromatic L-amino acid decarboxylase deficiency	3.000
90	Retinitis pigmentosa	2.925
20	Adrenoleukodystrophy	2.870
158	Tuberous sclerosis	2.778
1	Spinal and bulbar muscular atrophy	2.740
64	Thrombotic thrombocytopenic purpura	2.683
26	HTLV-1-associated myelopathy	2.656
61	Autoimmune hemolytic anemia	2.638
265	Lipodystrophy	2.573
10	Charcot-Marie-Tooth disease	2.535
234	Peroxisomal disease (except Adrenoleukodystrophy)	2.364
251	Urea cycle disorder	2.293
43	Microscopic polyangiitis	2.095
266	Familial mediterranean fever	2.095
280	Huge arteriovenous malformation with cervicofacial or limb lesion	2.095
227	Osler disease	2.077
268	Nakajo-Nishimura syndrome	2.000
325	Hereditary autoinflammatory syndrome	2.000
337	Homocystinuria	2.000
257	Hepatic glycogenosis	2.000
282	Congenital dyserythropoietic anemia	2.000
193	Prader-Willi syndrome	1.774
114	Non-dystrophic myotonia syndrome	1.736
288	Autoimmune acquired coagulation factor deficiency	1.736
15	Inclusion body myositis	1.650
236	Pseudohypoparathyroidism	1.611
37	Generalised pustular psoriasis	1.611
127	Frontotemporal lobar degeneration	1.488
98	Eosinophilic gastrointestinal disease	1.469
172	Hypophosphatasia	1.359
22	Moyamoya disease	1.288
118	Myelomeningocele	1.233
212	Tricuspid atresia	1.233
331	Idiopathic multicentric castleman disease	1.210
5	Progressive supranuclear palsy	1.182
246	Methylmalonic acidemia	1.176
169	Menkes disease	1.115
170	Occipital horn syndrome	1.115
254	Porphyria	1.085
238	Vitamin D-resistant rickets	1.038
235	Hypoparathyroidism	1.038
71	Idiopathic osteonecrosis of the femoral head	1.038
108	TNF receptor-associated periodic syndrome	1.000
267	Hyper-IgD syndrome	1.000
317	Trifunctional protein deficiency	1.000
54	Adult still disease	1.000
191	Werner syndrome	1.000
220	Rapidly progressive glomerulonephritis	1.000
30	Distal myopathy	1.000