DR info

Clinical trials : 646 / Drugs : 471 - (DrugBank : 105) / Drug target genes : 59 - Drug target pathways : 170

Muscular dystrophy and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
113	Muscular dystrophy	-
46	Malignant rheumatoid arthritis	34.049
13	Multiple sclerosis/Neuromyelitis optica	31.809
96	Crohn disease	30.186
6	Parkinson disease	29.859
2	Amyotrophic lateral sclerosis	24.903
97	Ulcerative colitis	16.169
8	Huntington disease	15.959
85	Idiopathic interstitial pneumonia	15.277
107	Juvenile idiopathic arthritis	15.173
49	Systemic lupus erythematosus	14.774
86	Pulmonary arterial hypertension	14.195
70	Spinal stenosis	13.857
226	Interstitial cystitis with Hunners ulcer	12.946
58	Hypertrophic cardiomyopathy	12.288
65	Primary immunodeficiency	11.576
299	Cystic fibrosis	10.433
17	Multiple system atrophy	10.131
222	Primary nephrotic syndrome	10.131
38	Stevens-Johnson syndrome	10.088
127	Frontotemporal lobar degeneration	10.042
51	Scleroderma	9.988
11	Myasthenia gravis	9.470
28	Systemic amyloidosis	8.903
215	Tetralogy of Fallot	8.814
206	Fragile X syndrome	8.708
78	Hypopituitarism	8.579
5	Progressive supranuclear palsy	8.063
21	Mitochondrial disease	7.384
34	Neurofibromatosis	7.263
168	Ehlers-Danlos syndrome	7.232
57	Idiopathic dilated cardiomyopathy	7.232
169	Menkes disease	7.232
170	Occipital horn syndrome	7.232
53	Sjogren syndrome	6.864
36	Epidermolysis bullosa	6.373
118	Myelomeningocele	6.229
224	Purpura nephritis	5.949
66	IgA nephropathy	5.718
158	Tuberous sclerosis	5.718
285	Fanconi anemia	5.332
60	Aplastic anemia	5.172
1	Spinal and bulbar muscular atrophy	5.149
302	Leber hereditary optic neuropathy	5.000
22	Moyamoya disease	4.661
3	Spinal muscular atrophy	4.605
64	Thrombotic thrombocytopenic purpura	4.542
227	Osler disease	4.357
210	Single Ventricle	4.290
151	Rasmussen encephalitis	4.237
83	Addison disease	4.237
41	Giant cell arteritis	4.212
164	Oculocutaneous albinism	4.138
19	Lysosomal storage disease	4.103
50	Dermatomyositis	4.102
4	Primary lateral sclerosis	3.996
274	Osteogenesis Imperfecta	3.915
298	Hereditary pancreatitis	3.908
84	Sarcoidosis	3.840
269	Pyogenic arthritis	3.710
256	Muscle glycogenosis	3.587
39	Toxic epidermal necrolysis	3.550
18	Spinocerebellar degeneration	3.540
63	Idiopathic thrombocytopenic purpura	3.540
228	Bronchiolitis obliterans	3.453
90	Retinitis pigmentosa	3.390
156	Rett syndrome	3.329
193	Prader-Willi syndrome	3.323
81	Congenital adrenal hyperplasia	3.305
286	Hereditary sideroblastic anemia	3.284
45	Eosinophilic granulomatosis with Polyangiitis	3.230
288	Autoimmune acquired coagulation factor deficiency	3.230
283	Acquired pure red cell aplasia	3.230
67	Polycystic kidney disease	3.179
95	Autoimmune hepatitis	3.103
171	Wilson disease	3.000
323	Aromatic L-amino acid decarboxylase deficiency	3.000
225	Congenital nephrogenic diabetes insipidus	2.929
280	Huge arteriovenous malformation with cervicofacial or limb lesion	2.920
62	Paroxysmal nocturnal hemoglobinuria	2.887
284	Diamond-Blackfan anemia	2.794
218	Alport syndrome	2.757
76	Pituitary gonadotropin secretion hyperthyroidism	2.757
93	Primary biliary cholangitis	2.665
231	Alpha-1-antitrypsin deficiency	2.665
326	Osteopetrosis	2.631
56	Behcet disease	2.621
40	Takayasu arteritis	2.558
205	Fragile X syndrome related disease	2.558
10	Charcot-Marie-Tooth disease	2.504
42	Polyarteritis nodosa	2.492
75	Cushing disease	2.480
271	Ankylosing spondylitis	2.434
160	Congenital ichthyosis	2.407
55	Relapsing polychondritis	2.331
234	Peroxisomal disease (except Adrenoleukodystrophy)	2.331
251	Urea cycle disorder	2.288
333	Hutchinson-Gilford syndrome	2.288
71	Idiopathic osteonecrosis of the femoral head	2.288
162	Pemphigoid	2.139
212	Tricuspid atresia	2.136
20	Adrenoleukodystrophy	2.080
203	22q11.2 deletion syndrome	2.058
77	Growth hormone secreting pituitary adenoma	2.000
337	Homocystinuria	2.000
257	Hepatic glycogenosis	2.000
282	Congenital dyserythropoietic anemia	2.000
26	HTLV-1-associated myelopathy	1.967
61	Autoimmune hemolytic anemia	1.904
294	Congenital diaphragmatic hernia	1.861
211	Hypoplastic left heart syndrome	1.861
278	Huge lymphatic malformation with cervicofacial lesion	1.861
167	Marfan syndrome	1.763
114	Non-dystrophic myotonia syndrome	1.695
265	Lipodystrophy	1.304
74	Prolactin secreting pituitary adenoma	1.203
301	Macular dystrophy	1.102
179	Williams syndrome	1.102
238	Vitamin D-resistant rickets	1.034
235	Hypoparathyroidism	1.034
111	Congenital myopathy	1.000
108	TNF receptor-associated periodic syndrome	1.000
267	Hyper-IgD syndrome	1.000
191	Werner syndrome	1.000
220	Rapidly progressive glomerulonephritis	1.000
30	Distal myopathy	1.000