140. Dorabe syndrome Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 116 / Drugs : 65 - (DrugBank : 17) / Drug target genes : 50 - Drug target pathways : 64
Dorabe syndrome and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 140 | Dorabe syndrome | - |
| 6 | Parkinson disease | 46.266 |
| 144 | Lennox-Gastaut syndrome | 41.250 |
| 156 | Rett syndrome | 38.205 |
| 2 | Amyotrophic lateral sclerosis | 38.032 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 37.579 |
| 97 | Ulcerative colitis | 36.735 |
| 193 | Prader-Willi syndrome | 35.982 |
| 8 | Huntington disease | 35.083 |
| 17 | Multiple system atrophy | 26.929 |
| 206 | Fragile X syndrome | 26.324 |
| 201 | Angelman syndrome | 22.000 |
| 298 | Hereditary pancreatitis | 21.205 |
| 18 | Spinocerebellar degeneration | 20.969 |
| 5 | Progressive supranuclear palsy | 20.094 |
| 145 | West syndrome | 19.793 |
| 70 | Spinal stenosis | 18.778 |
| 3 | Spinal muscular atrophy | 18.671 |
| 272 | Fibrodysplasia ossificans progressiva | 17.308 |
| 96 | Crohn disease | 17.086 |
| 36 | Epidermolysis bullosa | 16.644 |
| 231 | Alpha-1-antitrypsin deficiency | 16.275 |
| 152 | PCDH19 related syndrome | 16.000 |
| 46 | Malignant rheumatoid arthritis | 14.640 |
| 155 | Acquired aphasia with convulsive disorder | 13.733 |
| 158 | Tuberous sclerosis | 12.536 |
| 84 | Sarcoidosis | 12.213 |
| 205 | Fragile X syndrome related disease | 12.160 |
| 34 | Neurofibromatosis | 12.039 |
| 22 | Moyamoya disease | 11.429 |
| 21 | Mitochondrial disease | 11.059 |
| 98 | Eosinophilic gastrointestinal disease | 10.573 |
| 296 | Biliary atresia | 9.126 |
| 75 | Cushing disease | 9.031 |
| 203 | 22q11.2 deletion syndrome | 6.388 |
| 86 | Pulmonary arterial hypertension | 6.234 |
| 90 | Retinitis pigmentosa | 5.204 |
| 226 | Interstitial cystitis with Hunners ulcer | 4.688 |
| 51 | Scleroderma | 3.346 |
| 114 | Non-dystrophic myotonia syndrome | 3.346 |
| 58 | Hypertrophic cardiomyopathy | 3.059 |
| 7 | Corticobasal degeneration | 3.009 |
| 168 | Ehlers-Danlos syndrome | 3.009 |
| 1 | Spinal and bulbar muscular atrophy | 2.760 |
| 149 | Hemiconvulsion hemiplegia epilepsy syndrome | 2.603 |
| 10 | Charcot-Marie-Tooth disease | 2.557 |
| 4 | Primary lateral sclerosis | 2.408 |
| 309 | Progressive myoclonus epilepsy | 2.297 |
| 127 | Frontotemporal lobar degeneration | 2.067 |
| 38 | Stevens-Johnson syndrome | 2.014 |
| 74 | Prolactin secreting pituitary adenoma | 1.921 |
| 167 | Marfan syndrome | 1.800 |
| 164 | Oculocutaneous albinism | 1.676 |
| 81 | Congenital adrenal hyperplasia | 1.556 |
| 299 | Cystic fibrosis | 1.457 |
| 187 | Kabuki syndrome | 1.361 |
| 256 | Muscle glycogenosis | 1.243 |
| 179 | Williams syndrome | 1.125 |
| 254 | Porphyria | 1.105 |