144. Lennox-Gastaut syndrome Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 111 / Drugs : 72 - (DrugBank : 14) / Drug target genes : 49 - Drug target pathways : 61
Lennox-Gastaut syndrome and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 144 | Lennox-Gastaut syndrome | - |
| 140 | Dorabe syndrome | 41.250 |
| 6 | Parkinson disease | 38.939 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 36.947 |
| 156 | Rett syndrome | 36.470 |
| 97 | Ulcerative colitis | 36.225 |
| 2 | Amyotrophic lateral sclerosis | 35.902 |
| 193 | Prader-Willi syndrome | 35.826 |
| 8 | Huntington disease | 33.328 |
| 206 | Fragile X syndrome | 23.520 |
| 145 | West syndrome | 22.639 |
| 298 | Hereditary pancreatitis | 21.053 |
| 18 | Spinocerebellar degeneration | 20.847 |
| 17 | Multiple system atrophy | 18.998 |
| 3 | Spinal muscular atrophy | 18.531 |
| 5 | Progressive supranuclear palsy | 17.465 |
| 70 | Spinal stenosis | 17.393 |
| 272 | Fibrodysplasia ossificans progressiva | 17.268 |
| 96 | Crohn disease | 16.826 |
| 36 | Epidermolysis bullosa | 16.524 |
| 231 | Alpha-1-antitrypsin deficiency | 16.200 |
| 152 | PCDH19 related syndrome | 16.000 |
| 46 | Malignant rheumatoid arthritis | 15.511 |
| 155 | Acquired aphasia with convulsive disorder | 13.681 |
| 201 | Angelman syndrome | 13.061 |
| 158 | Tuberous sclerosis | 12.469 |
| 205 | Fragile X syndrome related disease | 12.121 |
| 84 | Sarcoidosis | 12.073 |
| 34 | Neurofibromatosis | 11.897 |
| 22 | Moyamoya disease | 11.382 |
| 98 | Eosinophilic gastrointestinal disease | 10.501 |
| 21 | Mitochondrial disease | 9.914 |
| 296 | Biliary atresia | 9.056 |
| 75 | Cushing disease | 8.005 |
| 203 | 22q11.2 deletion syndrome | 6.376 |
| 226 | Interstitial cystitis with Hunners ulcer | 4.638 |
| 149 | Hemiconvulsion hemiplegia epilepsy syndrome | 4.456 |
| 86 | Pulmonary arterial hypertension | 4.026 |
| 114 | Non-dystrophic myotonia syndrome | 3.333 |
| 58 | Hypertrophic cardiomyopathy | 3.031 |
| 168 | Ehlers-Danlos syndrome | 3.005 |
| 1 | Spinal and bulbar muscular atrophy | 2.755 |
| 51 | Scleroderma | 2.745 |
| 10 | Charcot-Marie-Tooth disease | 2.551 |
| 90 | Retinitis pigmentosa | 2.399 |
| 127 | Frontotemporal lobar degeneration | 2.050 |
| 38 | Stevens-Johnson syndrome | 2.007 |
| 167 | Marfan syndrome | 1.796 |
| 81 | Congenital adrenal hyperplasia | 1.551 |
| 256 | Muscle glycogenosis | 1.234 |
| 28 | Systemic amyloidosis | 1.213 |
| 202 | Smith-Magenis syndrome | 1.041 |