DR info

Clinical trials : 44 / Drugs : 61 - (DrugBank : 23) / Drug target genes : 57 - Drug target pathways : 83

Rett syndrome and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
156	Rett syndrome	-
13	Multiple sclerosis/Neuromyelitis optica	75.295
2	Amyotrophic lateral sclerosis	60.189
96	Crohn disease	47.218
6	Parkinson disease	43.883
140	Dorabe syndrome	38.205
97	Ulcerative colitis	37.287
144	Lennox-Gastaut syndrome	36.470
8	Huntington disease	33.733
193	Prader-Willi syndrome	33.094
206	Fragile X syndrome	32.297
5	Progressive supranuclear palsy	28.720
18	Spinocerebellar degeneration	27.971
17	Multiple system atrophy	25.596
3	Spinal muscular atrophy	23.313
70	Spinal stenosis	21.179
298	Hereditary pancreatitis	19.595
205	Fragile X syndrome related disease	18.556
46	Malignant rheumatoid arthritis	18.502
21	Mitochondrial disease	17.097
272	Fibrodysplasia ossificans progressiva	16.583
145	West syndrome	16.162
152	PCDH19 related syndrome	16.000
98	Eosinophilic gastrointestinal disease	15.919
231	Alpha-1-antitrypsin deficiency	14.891
36	Epidermolysis bullosa	14.441
203	22q11.2 deletion syndrome	14.000
201	Angelman syndrome	13.989
296	Biliary atresia	12.855
155	Acquired aphasia with convulsive disorder	12.768
158	Tuberous sclerosis	12.458
84	Sarcoidosis	11.394
34	Neurofibromatosis	11.134
22	Moyamoya disease	10.568
226	Interstitial cystitis with Hunners ulcer	8.087
86	Pulmonary arterial hypertension	7.408
75	Cushing disease	7.385
127	Frontotemporal lobar degeneration	5.706
113	Muscular dystrophy	3.329
299	Cystic fibrosis	3.136
58	Hypertrophic cardiomyopathy	3.111
114	Non-dystrophic myotonia syndrome	3.111
254	Porphyria	2.981
51	Scleroderma	2.946
168	Ehlers-Danlos syndrome	2.922
53	Sjogren syndrome	2.881
78	Hypopituitarism	2.678
1	Spinal and bulbar muscular atrophy	2.662
10	Charcot-Marie-Tooth disease	2.450
4	Primary lateral sclerosis	2.215
120	Hereditary dystonia	2.000
179	Williams syndrome	1.893
38	Stevens-Johnson syndrome	1.883
167	Marfan syndrome	1.725
49	Systemic lupus erythematosus	1.679
215	Tetralogy of Fallot	1.623
90	Retinitis pigmentosa	1.545
256	Muscle glycogenosis	1.538
81	Congenital adrenal hyperplasia	1.472
187	Kabuki syndrome	1.351
50	Dermatomyositis	1.159
149	Hemiconvulsion hemiplegia epilepsy syndrome	1.100
85	Idiopathic interstitial pneumonia	1.086