169. Menkes disease Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 6 / Drugs : 6 - (DrugBank : 4) / Drug target genes : 9 - Drug target pathways : 14
Menkes disease and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 169 | Menkes disease | - |
| 170 | Occipital horn syndrome | 9.000 |
| 6 | Parkinson disease | 9.000 |
| 17 | Multiple system atrophy | 9.000 |
| 46 | Malignant rheumatoid arthritis | 9.000 |
| 96 | Crohn disease | 9.000 |
| 5 | Progressive supranuclear palsy | 9.000 |
| 11 | Myasthenia gravis | 9.000 |
| 22 | Moyamoya disease | 9.000 |
| 70 | Spinal stenosis | 9.000 |
| 113 | Muscular dystrophy | 7.232 |
| 118 | Myelomeningocele | 6.806 |
| 2 | Amyotrophic lateral sclerosis | 5.508 |
| 280 | Huge arteriovenous malformation with cervicofacial or limb lesion | 4.857 |
| 215 | Tetralogy of Fallot | 4.667 |
| 288 | Autoimmune acquired coagulation factor deficiency | 4.667 |
| 206 | Fragile X syndrome | 4.222 |
| 8 | Huntington disease | 4.143 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 4.045 |
| 57 | Idiopathic dilated cardiomyopathy | 4.012 |
| 210 | Single Ventricle | 3.125 |
| 323 | Aromatic L-amino acid decarboxylase deficiency | 3.000 |
| 226 | Interstitial cystitis with Hunners ulcer | 2.951 |
| 85 | Idiopathic interstitial pneumonia | 2.890 |
| 86 | Pulmonary arterial hypertension | 2.889 |
| 278 | Huge lymphatic malformation with cervicofacial lesion | 2.200 |
| 67 | Polycystic kidney disease | 2.012 |
| 127 | Frontotemporal lobar degeneration | 2.000 |
| 58 | Hypertrophic cardiomyopathy | 1.963 |
| 28 | Systemic amyloidosis | 1.912 |
| 212 | Tricuspid atresia | 1.750 |
| 167 | Marfan syndrome | 1.600 |
| 4 | Primary lateral sclerosis | 1.316 |
| 254 | Porphyria | 1.316 |
| 227 | Osler disease | 1.261 |
| 158 | Tuberous sclerosis | 1.171 |
| 78 | Hypopituitarism | 1.136 |
| 296 | Biliary atresia | 1.133 |
| 21 | Mitochondrial disease | 1.128 |
| 90 | Retinitis pigmentosa | 1.122 |
| 107 | Juvenile idiopathic arthritis | 1.115 |
| 34 | Neurofibromatosis | 1.069 |
| 65 | Primary immunodeficiency | 1.067 |
| 157 | Sturge-Weber syndrome | 1.067 |
| 111 | Congenital myopathy | 1.000 |