DR info

Clinical trials : 119 / Drugs : 138 - (DrugBank : 44) / Drug target genes : 59 - Drug target pathways : 111

Multiple system atrophy and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
17	Multiple system atrophy	-
6	Parkinson disease	56.028
2	Amyotrophic lateral sclerosis	42.107
5	Progressive supranuclear palsy	41.368
13	Multiple sclerosis/Neuromyelitis optica	39.616
206	Fragile X syndrome	36.430
8	Huntington disease	34.119
46	Malignant rheumatoid arthritis	27.900
18	Spinocerebellar degeneration	27.605
97	Ulcerative colitis	27.480
140	Dorabe syndrome	26.929
156	Rett syndrome	25.596
3	Spinal muscular atrophy	24.672
96	Crohn disease	24.407
70	Spinal stenosis	24.163
22	Moyamoya disease	23.419
193	Prader-Willi syndrome	22.437
201	Angelman syndrome	22.000
21	Mitochondrial disease	19.334
144	Lennox-Gastaut syndrome	18.998
205	Fragile X syndrome related disease	18.797
152	PCDH19 related syndrome	16.000
296	Biliary atresia	14.811
158	Tuberous sclerosis	14.239
203	22q11.2 deletion syndrome	14.000
98	Eosinophilic gastrointestinal disease	13.115
145	West syndrome	12.458
36	Epidermolysis bullosa	12.044
272	Fibrodysplasia ossificans progressiva	11.460
4	Primary lateral sclerosis	11.161
75	Cushing disease	10.894
155	Acquired aphasia with convulsive disorder	10.709
231	Alpha-1-antitrypsin deficiency	10.694
34	Neurofibromatosis	10.553
215	Tetralogy of Fallot	10.158
113	Muscular dystrophy	10.131
84	Sarcoidosis	9.836
169	Menkes disease	9.000
170	Occipital horn syndrome	9.000
127	Frontotemporal lobar degeneration	7.930
298	Hereditary pancreatitis	7.760
118	Myelomeningocele	6.225
86	Pulmonary arterial hypertension	6.085
57	Idiopathic dilated cardiomyopathy	5.623
85	Idiopathic interstitial pneumonia	4.739
78	Hypopituitarism	4.238
7	Corticobasal degeneration	4.197
280	Huge arteriovenous malformation with cervicofacial or limb lesion	3.902
299	Cystic fibrosis	3.566
11	Myasthenia gravis	3.497
49	Systemic lupus erythematosus	3.375
278	Huge lymphatic malformation with cervicofacial lesion	3.252
288	Autoimmune acquired coagulation factor deficiency	3.213
323	Aromatic L-amino acid decarboxylase deficiency	3.000
90	Retinitis pigmentosa	2.737
167	Marfan syndrome	2.705
67	Polycystic kidney disease	2.513
226	Interstitial cystitis with Hunners ulcer	2.407
309	Progressive myoclonus epilepsy	2.287
58	Hypertrophic cardiomyopathy	2.208
210	Single Ventricle	2.159
164	Oculocutaneous albinism	2.079
66	IgA nephropathy	2.043
120	Hereditary dystonia	2.000
179	Williams syndrome	1.923
157	Sturge-Weber syndrome	1.859
74	Prolactin secreting pituitary adenoma	1.844
254	Porphyria	1.618
218	Alport syndrome	1.574
19	Lysosomal storage disease	1.432
212	Tricuspid atresia	1.217
222	Primary nephrotic syndrome	1.122
137	Focal cortical dysplasia	1.000
192	Cockayne syndrome	1.000
277	Lymphangiomatosis	1.000
281	Klippel-Trenaunay-Weber syndrome	1.000
111	Congenital myopathy	1.000
52	Mixed connective tissue disease	1.000