DR info

Clinical trials : 113 / Drugs : 111 - (DrugBank : 26) / Drug target genes : 48 - Drug target pathways : 102

Prader-Willi syndrome and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
193	Prader-Willi syndrome	-
6	Parkinson disease	42.594
13	Multiple sclerosis/Neuromyelitis optica	42.270
140	Dorabe syndrome	35.982
144	Lennox-Gastaut syndrome	35.826
156	Rett syndrome	33.094
97	Ulcerative colitis	30.888
2	Amyotrophic lateral sclerosis	27.628
8	Huntington disease	25.929
206	Fragile X syndrome	23.208
17	Multiple system atrophy	22.437
96	Crohn disease	21.086
298	Hereditary pancreatitis	20.767
5	Progressive supranuclear palsy	19.572
3	Spinal muscular atrophy	19.507
70	Spinal stenosis	19.492
18	Spinocerebellar degeneration	19.336
36	Epidermolysis bullosa	17.517
46	Malignant rheumatoid arthritis	17.284
272	Fibrodysplasia ossificans progressiva	17.195
231	Alpha-1-antitrypsin deficiency	16.059
152	PCDH19 related syndrome	16.000
145	West syndrome	15.468
84	Sarcoidosis	15.013
158	Tuberous sclerosis	14.790
22	Moyamoya disease	13.840
34	Neurofibromatosis	13.711
155	Acquired aphasia with convulsive disorder	13.582
205	Fragile X syndrome related disease	13.373
201	Angelman syndrome	13.005
75	Cushing disease	12.831
21	Mitochondrial disease	11.898
98	Eosinophilic gastrointestinal disease	10.366
296	Biliary atresia	9.948
203	22q11.2 deletion syndrome	6.353
226	Interstitial cystitis with Hunners ulcer	6.065
168	Ehlers-Danlos syndrome	5.658
86	Pulmonary arterial hypertension	5.265
58	Hypertrophic cardiomyopathy	3.636
81	Congenital adrenal hyperplasia	3.353
113	Muscular dystrophy	3.323
114	Non-dystrophic myotonia syndrome	3.309
157	Sturge-Weber syndrome	3.263
127	Frontotemporal lobar degeneration	3.256
51	Scleroderma	3.212
167	Marfan syndrome	2.745
1	Spinal and bulbar muscular atrophy	2.745
10	Charcot-Marie-Tooth disease	2.540
67	Polycystic kidney disease	2.073
38	Stevens-Johnson syndrome	1.993
90	Retinitis pigmentosa	1.824
107	Juvenile idiopathic arthritis	1.774
256	Muscle glycogenosis	1.731
28	Systemic amyloidosis	1.601
78	Hypopituitarism	1.428
50	Dermatomyositis	1.368
72	Pituitary ADH secretion disorder	1.039
137	Focal cortical dysplasia	1.000
192	Cockayne syndrome	1.000
277	Lymphangiomatosis	1.000
281	Klippel-Trenaunay-Weber syndrome	1.000
191	Werner syndrome	1.000