201. Angelman syndrome Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 25 / Drugs : 40 - (DrugBank : 11) / Drug target genes : 22 - Drug target pathways : 20
Angelman syndrome and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 201 | Angelman syndrome | - |
| 6 | Parkinson disease | 22.000 |
| 2 | Amyotrophic lateral sclerosis | 22.000 |
| 17 | Multiple system atrophy | 22.000 |
| 140 | Dorabe syndrome | 22.000 |
| 8 | Huntington disease | 16.995 |
| 152 | PCDH19 related syndrome | 16.000 |
| 206 | Fragile X syndrome | 15.818 |
| 5 | Progressive supranuclear palsy | 15.634 |
| 97 | Ulcerative colitis | 15.139 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 14.949 |
| 21 | Mitochondrial disease | 14.534 |
| 205 | Fragile X syndrome related disease | 14.429 |
| 272 | Fibrodysplasia ossificans progressiva | 14.322 |
| 145 | West syndrome | 14.222 |
| 75 | Cushing disease | 14.196 |
| 70 | Spinal stenosis | 14.132 |
| 22 | Moyamoya disease | 14.130 |
| 155 | Acquired aphasia with convulsive disorder | 14.044 |
| 156 | Rett syndrome | 13.989 |
| 231 | Alpha-1-antitrypsin deficiency | 13.631 |
| 158 | Tuberous sclerosis | 13.631 |
| 46 | Malignant rheumatoid arthritis | 13.491 |
| 98 | Eosinophilic gastrointestinal disease | 13.339 |
| 18 | Spinocerebellar degeneration | 13.188 |
| 296 | Biliary atresia | 13.188 |
| 36 | Epidermolysis bullosa | 13.061 |
| 144 | Lennox-Gastaut syndrome | 13.061 |
| 193 | Prader-Willi syndrome | 13.005 |
| 298 | Hereditary pancreatitis | 12.954 |
| 3 | Spinal muscular atrophy | 12.954 |
| 84 | Sarcoidosis | 12.488 |
| 34 | Neurofibromatosis | 12.439 |
| 96 | Crohn disease | 12.052 |
| 7 | Corticobasal degeneration | 3.283 |
| 4 | Primary lateral sclerosis | 3.014 |
| 164 | Oculocutaneous albinism | 2.406 |
| 309 | Progressive myoclonus epilepsy | 2.352 |
| 74 | Prolactin secreting pituitary adenoma | 2.344 |
| 90 | Retinitis pigmentosa | 2.171 |
| 299 | Cystic fibrosis | 1.338 |