DR info

Clinical trials : 18 / Drugs : 26 - (DrugBank : 14) / Drug target genes : 13 - Drug target pathways : 45

Tetralogy of Fallot and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
215	Tetralogy of Fallot	-
6	Parkinson disease	14.374
5	Progressive supranuclear palsy	11.559
46	Malignant rheumatoid arthritis	11.124
13	Multiple sclerosis/Neuromyelitis optica	11.053
17	Multiple system atrophy	10.158
70	Spinal stenosis	10.100
96	Crohn disease	9.668
113	Muscular dystrophy	8.814
85	Idiopathic interstitial pneumonia	8.485
2	Amyotrophic lateral sclerosis	8.279
127	Frontotemporal lobar degeneration	5.513
4	Primary lateral sclerosis	5.427
78	Hypopituitarism	5.420
3	Spinal muscular atrophy	5.264
169	Menkes disease	4.667
170	Occipital horn syndrome	4.667
21	Mitochondrial disease	4.312
206	Fragile X syndrome	4.214
8	Huntington disease	3.979
86	Pulmonary arterial hypertension	3.911
323	Aromatic L-amino acid decarboxylase deficiency	3.000
97	Ulcerative colitis	2.932
22	Moyamoya disease	2.857
203	22q11.2 deletion syndrome	2.679
11	Myasthenia gravis	2.533
58	Hypertrophic cardiomyopathy	2.500
90	Retinitis pigmentosa	2.490
118	Myelomeningocele	2.444
226	Interstitial cystitis with Hunners ulcer	2.375
34	Neurofibromatosis	2.276
65	Primary immunodeficiency	2.267
49	Systemic lupus erythematosus	2.211
167	Marfan syndrome	2.133
205	Fragile X syndrome related disease	2.111
278	Huge lymphatic malformation with cervicofacial lesion	2.000
18	Spinocerebellar degeneration	1.790
280	Huge arteriovenous malformation with cervicofacial or limb lesion	1.778
222	Primary nephrotic syndrome	1.685
156	Rett syndrome	1.623
288	Autoimmune acquired coagulation factor deficiency	1.580
102	Rubinstein-Taybi syndrome	1.571
212	Tricuspid atresia	1.438
227	Osler disease	1.430
89	Lymphangioleiomyomatosis	1.350
57	Idiopathic dilated cardiomyopathy	1.333
256	Muscle glycogenosis	1.290
233	Wolfram syndrome	1.182
111	Congenital myopathy	1.000