DR info

Clinical trials : 17 / Drugs : 22 - (DrugBank : 17) / Drug target genes : 33 - Drug target pathways : 45

Moyamoya disease and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
22	Moyamoya disease	-
70	Spinal stenosis	28.000
6	Parkinson disease	28.000
46	Malignant rheumatoid arthritis	28.000
96	Crohn disease	28.000
5	Progressive supranuclear palsy	26.436
17	Multiple system atrophy	23.419
2	Amyotrophic lateral sclerosis	22.711
13	Multiple sclerosis/Neuromyelitis optica	22.573
206	Fragile X syndrome	22.095
158	Tuberous sclerosis	18.900
8	Huntington disease	18.520
21	Mitochondrial disease	18.096
34	Neurofibromatosis	17.017
296	Biliary atresia	16.825
231	Alpha-1-antitrypsin deficiency	16.208
152	PCDH19 related syndrome	16.000
3	Spinal muscular atrophy	15.082
201	Angelman syndrome	14.130
193	Prader-Willi syndrome	13.840
298	Hereditary pancreatitis	13.755
205	Fragile X syndrome related disease	13.531
272	Fibrodysplasia ossificans progressiva	13.363
145	West syndrome	13.206
155	Acquired aphasia with convulsive disorder	12.926
18	Spinocerebellar degeneration	12.844
97	Ulcerative colitis	12.381
98	Eosinophilic gastrointestinal disease	11.819
140	Dorabe syndrome	11.429
144	Lennox-Gastaut syndrome	11.382
36	Epidermolysis bullosa	11.382
75	Cushing disease	10.912
156	Rett syndrome	10.568
84	Sarcoidosis	10.481
169	Menkes disease	9.000
170	Occipital horn syndrome	9.000
118	Myelomeningocele	6.344
11	Myasthenia gravis	5.954
113	Muscular dystrophy	4.661
280	Huge arteriovenous malformation with cervicofacial or limb lesion	3.306
57	Idiopathic dilated cardiomyopathy	3.175
323	Aromatic L-amino acid decarboxylase deficiency	3.000
210	Single Ventricle	2.898
215	Tetralogy of Fallot	2.857
288	Autoimmune acquired coagulation factor deficiency	2.857
226	Interstitial cystitis with Hunners ulcer	2.324
86	Pulmonary arterial hypertension	2.118
337	Homocystinuria	2.000
278	Huge lymphatic malformation with cervicofacial lesion	1.929
58	Hypertrophic cardiomyopathy	1.875
78	Hypopituitarism	1.360
212	Tricuspid atresia	1.326
107	Juvenile idiopathic arthritis	1.288
28	Systemic amyloidosis	1.204
167	Marfan syndrome	1.125
65	Primary immunodeficiency	1.121
85	Idiopathic interstitial pneumonia	1.100
251	Urea cycle disorder	1.071
111	Congenital myopathy	1.000