DR info

Clinical trials : 56 / Drugs : 72 - (DrugBank : 21) / Drug target genes : 23 - Drug target pathways : 136

Osler disease and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
227	Osler disease	-
85	Idiopathic interstitial pneumonia	16.330
228	Bronchiolitis obliterans	13.491
51	Scleroderma	10.475
46	Malignant rheumatoid arthritis	8.936
13	Multiple sclerosis/Neuromyelitis optica	8.810
28	Systemic amyloidosis	8.461
89	Lymphangioleiomyomatosis	7.599
151	Rasmussen encephalitis	6.000
96	Crohn disease	5.637
226	Interstitial cystitis with Hunners ulcer	5.231
39	Toxic epidermal necrolysis	5.229
302	Leber hereditary optic neuropathy	5.000
6	Parkinson disease	4.648
53	Sjogren syndrome	4.418
38	Stevens-Johnson syndrome	4.403
113	Muscular dystrophy	4.357
65	Primary immunodeficiency	4.070
299	Cystic fibrosis	4.035
86	Pulmonary arterial hypertension	4.015
158	Tuberous sclerosis	3.975
49	Systemic lupus erythematosus	3.954
2	Amyotrophic lateral sclerosis	3.808
55	Relapsing polychondritis	3.783
11	Myasthenia gravis	3.710
58	Hypertrophic cardiomyopathy	3.652
286	Hereditary sideroblastic anemia	3.533
269	Pyogenic arthritis	3.339
285	Fanconi anemia	3.267
34	Neurofibromatosis	3.262
64	Thrombotic thrombocytopenic purpura	3.228
41	Giant cell arteritis	3.163
162	Pemphigoid	3.163
164	Oculocutaneous albinism	3.133
45	Eosinophilic granulomatosis with Polyangiitis	3.043
160	Congenital ichthyosis	3.043
95	Autoimmune hepatitis	2.966
60	Aplastic anemia	2.942
50	Dermatomyositis	2.841
284	Diamond-Blackfan anemia	2.775
20	Adrenoleukodystrophy	2.775
234	Peroxisomal disease (except Adrenoleukodystrophy)	2.717
222	Primary nephrotic syndrome	2.689
40	Takayasu arteritis	2.630
42	Polyarteritis nodosa	2.589
274	Osteogenesis Imperfecta	2.484
224	Purpura nephritis	2.391
326	Osteopetrosis	2.310
56	Behcet disease	2.304
26	HTLV-1-associated myelopathy	2.265
283	Acquired pure red cell aplasia	2.174
63	Idiopathic thrombocytopenic purpura	2.157
36	Epidermolysis bullosa	2.108
90	Retinitis pigmentosa	2.108
107	Juvenile idiopathic arthritis	2.077
62	Paroxysmal nocturnal hemoglobinuria	2.019
276	Achondroplasia	1.957
278	Huge lymphatic malformation with cervicofacial lesion	1.957
19	Lysosomal storage disease	1.951
61	Autoimmune hemolytic anemia	1.870
97	Ulcerative colitis	1.751
93	Primary biliary cholangitis	1.646
66	IgA nephropathy	1.646
215	Tetralogy of Fallot	1.430
169	Menkes disease	1.261
170	Occipital horn syndrome	1.261
167	Marfan syndrome	1.174
87	Pulmonary veno-occlusive disease	1.087
67	Polycystic kidney disease	1.043
111	Congenital myopathy	1.000