DR info

Clinical trials : 54 / Drugs : 61 - (DrugBank : 15) / Drug target genes : 3 - Drug target pathways : 28

Urea cycle disorder and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
251	Urea cycle disorder	-
300	IgG4-related disease	2.400
35	Pemphigus	2.352
271	Ankylosing spondylitis	2.305
78	Hypopituitarism	2.301
11	Myasthenia gravis	2.300
107	Juvenile idiopathic arthritis	2.293
298	Hereditary pancreatitis	2.292
3	Spinal muscular atrophy	2.292
113	Muscular dystrophy	2.288
222	Primary nephrotic syndrome	2.287
226	Interstitial cystitis with Hunners ulcer	2.285
70	Spinal stenosis	2.284
65	Primary immunodeficiency	2.275
299	Cystic fibrosis	2.273
86	Pulmonary arterial hypertension	2.272
51	Scleroderma	2.270
49	Systemic lupus erythematosus	2.270
97	Ulcerative colitis	2.266
96	Crohn disease	2.263
46	Malignant rheumatoid arthritis	2.262
6	Parkinson disease	2.262
13	Multiple sclerosis/Neuromyelitis optica	2.258
337	Homocystinuria	2.000
22	Moyamoya disease	1.071
225	Congenital nephrogenic diabetes insipidus	1.067
256	Muscle glycogenosis	1.065
210	Single Ventricle	1.062
231	Alpha-1-antitrypsin deficiency	1.057
158	Tuberous sclerosis	1.057
296	Biliary atresia	1.044
21	Mitochondrial disease	1.043
58	Hypertrophic cardiomyopathy	1.042
206	Fragile X syndrome	1.037
5	Progressive supranuclear palsy	1.031
28	Systemic amyloidosis	1.030
34	Neurofibromatosis	1.023
2	Amyotrophic lateral sclerosis	1.012
220	Rapidly progressive glomerulonephritis	1.000
30	Distal myopathy	1.000
245	Propionic acidemia	1.000