256. Muscle glycogenosis Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 180 / Drugs : 133 - (DrugBank : 29) / Drug target genes : 25 - Drug target pathways : 105
Muscle glycogenosis and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 256 | Muscle glycogenosis | - |
| 13 | Multiple sclerosis/Neuromyelitis optica | 17.578 |
| 46 | Malignant rheumatoid arthritis | 14.995 |
| 6 | Parkinson disease | 14.982 |
| 34 | Neurofibromatosis | 12.013 |
| 65 | Primary immunodeficiency | 11.961 |
| 51 | Scleroderma | 11.654 |
| 96 | Crohn disease | 11.260 |
| 127 | Frontotemporal lobar degeneration | 10.161 |
| 2 | Amyotrophic lateral sclerosis | 10.081 |
| 11 | Myasthenia gravis | 8.711 |
| 331 | Idiopathic multicentric castleman disease | 8.617 |
| 86 | Pulmonary arterial hypertension | 7.397 |
| 107 | Juvenile idiopathic arthritis | 7.339 |
| 49 | Systemic lupus erythematosus | 7.265 |
| 97 | Ulcerative colitis | 7.074 |
| 222 | Primary nephrotic syndrome | 7.060 |
| 102 | Rubinstein-Taybi syndrome | 7.000 |
| 89 | Lymphangioleiomyomatosis | 6.795 |
| 84 | Sarcoidosis | 6.648 |
| 53 | Sjogren syndrome | 6.250 |
| 3 | Spinal muscular atrophy | 5.376 |
| 5 | Progressive supranuclear palsy | 5.104 |
| 233 | Wolfram syndrome | 5.029 |
| 271 | Ankylosing spondylitis | 4.878 |
| 85 | Idiopathic interstitial pneumonia | 4.692 |
| 58 | Hypertrophic cardiomyopathy | 4.637 |
| 35 | Pemphigus | 4.223 |
| 26 | HTLV-1-associated myelopathy | 4.126 |
| 1 | Spinal and bulbar muscular atrophy | 4.065 |
| 113 | Muscular dystrophy | 3.587 |
| 28 | Systemic amyloidosis | 3.484 |
| 70 | Spinal stenosis | 3.484 |
| 231 | Alpha-1-antitrypsin deficiency | 3.421 |
| 44 | Wegener granulomatosis | 3.387 |
| 168 | Ehlers-Danlos syndrome | 3.136 |
| 40 | Takayasu arteritis | 3.098 |
| 38 | Stevens-Johnson syndrome | 3.097 |
| 36 | Epidermolysis bullosa | 3.034 |
| 298 | Hereditary pancreatitis | 2.960 |
| 283 | Acquired pure red cell aplasia | 2.774 |
| 10 | Charcot-Marie-Tooth disease | 2.713 |
| 50 | Dermatomyositis | 2.371 |
| 90 | Retinitis pigmentosa | 2.355 |
| 226 | Interstitial cystitis with Hunners ulcer | 2.173 |
| 19 | Lysosomal storage disease | 2.130 |
| 41 | Giant cell arteritis | 2.041 |
| 149 | Hemiconvulsion hemiplegia epilepsy syndrome | 2.040 |
| 8 | Huntington disease | 2.032 |
| 268 | Nakajo-Nishimura syndrome | 2.000 |
| 325 | Hereditary autoinflammatory syndrome | 2.000 |
| 337 | Homocystinuria | 2.000 |
| 114 | Non-dystrophic myotonia syndrome | 1.971 |
| 60 | Aplastic anemia | 1.853 |
| 193 | Prader-Willi syndrome | 1.731 |
| 156 | Rett syndrome | 1.538 |
| 285 | Fanconi anemia | 1.505 |
| 300 | IgG4-related disease | 1.445 |
| 162 | Pemphigoid | 1.442 |
| 228 | Bronchiolitis obliterans | 1.442 |
| 93 | Primary biliary cholangitis | 1.406 |
| 158 | Tuberous sclerosis | 1.406 |
| 172 | Hypophosphatasia | 1.376 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 1.290 |
| 215 | Tetralogy of Fallot | 1.290 |
| 140 | Dorabe syndrome | 1.243 |
| 144 | Lennox-Gastaut syndrome | 1.234 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 1.180 |
| 284 | Diamond-Blackfan anemia | 1.150 |
| 61 | Autoimmune hemolytic anemia | 1.074 |
| 251 | Urea cycle disorder | 1.065 |
| 42 | Polyarteritis nodosa | 1.052 |
| 299 | Cystic fibrosis | 1.025 |
| 277 | Lymphangiomatosis | 1.000 |
| 281 | Klippel-Trenaunay-Weber syndrome | 1.000 |
| 111 | Congenital myopathy | 1.000 |
| 52 | Mixed connective tissue disease | 1.000 |
| 137 | Focal cortical dysplasia | 1.000 |
| 192 | Cockayne syndrome | 1.000 |