26. HTLV-1-associated myelopathy Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 29 / Drugs : 47 - (DrugBank : 29) / Drug target genes : 34 - Drug target pathways : 119
HTLV-1-associated myelopathy and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 26 | HTLV-1-associated myelopathy | - |
| 2 | Amyotrophic lateral sclerosis | 24.786 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 21.407 |
| 85 | Idiopathic interstitial pneumonia | 21.316 |
| 65 | Primary immunodeficiency | 20.161 |
| 331 | Idiopathic multicentric castleman disease | 19.311 |
| 28 | Systemic amyloidosis | 15.825 |
| 49 | Systemic lupus erythematosus | 15.753 |
| 34 | Neurofibromatosis | 15.079 |
| 46 | Malignant rheumatoid arthritis | 13.838 |
| 42 | Polyarteritis nodosa | 13.748 |
| 56 | Behcet disease | 13.263 |
| 51 | Scleroderma | 11.097 |
| 6 | Parkinson disease | 10.460 |
| 93 | Primary biliary cholangitis | 9.812 |
| 53 | Sjogren syndrome | 8.397 |
| 90 | Retinitis pigmentosa | 7.684 |
| 222 | Primary nephrotic syndrome | 7.187 |
| 102 | Rubinstein-Taybi syndrome | 7.000 |
| 266 | Familial mediterranean fever | 6.547 |
| 39 | Toxic epidermal necrolysis | 6.278 |
| 19 | Lysosomal storage disease | 6.059 |
| 151 | Rasmussen encephalitis | 6.000 |
| 226 | Interstitial cystitis with Hunners ulcer | 5.329 |
| 5 | Progressive supranuclear palsy | 5.305 |
| 25 | Progressive multifocal leukoencephalopathy | 5.278 |
| 11 | Myasthenia gravis | 5.095 |
| 38 | Stevens-Johnson syndrome | 5.053 |
| 302 | Leber hereditary optic neuropathy | 5.000 |
| 233 | Wolfram syndrome | 4.923 |
| 299 | Cystic fibrosis | 4.816 |
| 164 | Oculocutaneous albinism | 4.799 |
| 40 | Takayasu arteritis | 4.604 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 4.491 |
| 283 | Acquired pure red cell aplasia | 4.491 |
| 60 | Aplastic anemia | 4.386 |
| 96 | Crohn disease | 4.376 |
| 285 | Fanconi anemia | 4.192 |
| 256 | Muscle glycogenosis | 4.126 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 4.090 |
| 210 | Single Ventricle | 4.063 |
| 41 | Giant cell arteritis | 4.005 |
| 284 | Diamond-Blackfan anemia | 3.981 |
| 269 | Pyogenic arthritis | 3.954 |
| 224 | Purpura nephritis | 3.954 |
| 64 | Thrombotic thrombocytopenic purpura | 3.788 |
| 160 | Congenital ichthyosis | 3.510 |
| 55 | Relapsing polychondritis | 3.474 |
| 58 | Hypertrophic cardiomyopathy | 3.419 |
| 95 | Autoimmune hepatitis | 3.393 |
| 286 | Hereditary sideroblastic anemia | 3.372 |
| 16 | Crow-Fukase syndrome | 3.284 |
| 162 | Pemphigoid | 3.215 |
| 228 | Bronchiolitis obliterans | 3.215 |
| 97 | Ulcerative colitis | 3.147 |
| 66 | IgA nephropathy | 3.128 |
| 127 | Frontotemporal lobar degeneration | 2.947 |
| 61 | Autoimmune hemolytic anemia | 2.888 |
| 63 | Idiopathic thrombocytopenic purpura | 2.807 |
| 89 | Lymphangioleiomyomatosis | 2.770 |
| 86 | Pulmonary arterial hypertension | 2.750 |
| 50 | Dermatomyositis | 2.737 |
| 107 | Juvenile idiopathic arthritis | 2.656 |
| 3 | Spinal muscular atrophy | 2.638 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 2.467 |
| 20 | Adrenoleukodystrophy | 2.325 |
| 227 | Osler disease | 2.265 |
| 98 | Eosinophilic gastrointestinal disease | 2.264 |
| 274 | Osteogenesis Imperfecta | 2.209 |
| 296 | Biliary atresia | 2.178 |
| 36 | Epidermolysis bullosa | 2.105 |
| 326 | Osteopetrosis | 2.015 |
| 113 | Muscular dystrophy | 1.967 |
| 158 | Tuberous sclerosis | 1.814 |
| 254 | Porphyria | 1.801 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |