280. Huge arteriovenous malformation with cervicofacial or limb lesion Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 27 / Drugs : 30 - (DrugBank : 15) / Drug target genes : 14 - Drug target pathways : 153
Huge arteriovenous malformation with cervicofacial or limb lesion and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 280 | Huge arteriovenous malformation with cervicofacial or limb lesion | - |
| 46 | Malignant rheumatoid arthritis | 8.783 |
| 96 | Crohn disease | 7.313 |
| 2 | Amyotrophic lateral sclerosis | 7.309 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 7.250 |
| 34 | Neurofibromatosis | 6.118 |
| 288 | Autoimmune acquired coagulation factor deficiency | 6.095 |
| 6 | Parkinson disease | 5.940 |
| 118 | Myelomeningocele | 5.143 |
| 70 | Spinal stenosis | 4.987 |
| 169 | Menkes disease | 4.857 |
| 170 | Occipital horn syndrome | 4.857 |
| 206 | Fragile X syndrome | 3.954 |
| 17 | Multiple system atrophy | 3.902 |
| 85 | Idiopathic interstitial pneumonia | 3.747 |
| 86 | Pulmonary arterial hypertension | 3.745 |
| 22 | Moyamoya disease | 3.306 |
| 11 | Myasthenia gravis | 3.029 |
| 323 | Aromatic L-amino acid decarboxylase deficiency | 3.000 |
| 279 | Huge venous malformation with cervical, oral and pharyngeal diffuse lesion | 3.000 |
| 113 | Muscular dystrophy | 2.920 |
| 226 | Interstitial cystitis with Hunners ulcer | 2.893 |
| 5 | Progressive supranuclear palsy | 2.888 |
| 8 | Huntington disease | 2.816 |
| 67 | Polycystic kidney disease | 2.209 |
| 58 | Hypertrophic cardiomyopathy | 2.121 |
| 107 | Juvenile idiopathic arthritis | 2.095 |
| 65 | Primary immunodeficiency | 1.964 |
| 51 | Scleroderma | 1.928 |
| 215 | Tetralogy of Fallot | 1.778 |
| 212 | Tricuspid atresia | 1.527 |
| 57 | Idiopathic dilated cardiomyopathy | 1.429 |
| 310 | Congenital anomalies syndrome | 1.429 |
| 127 | Frontotemporal lobar degeneration | 1.429 |
| 271 | Ankylosing spondylitis | 1.422 |
| 78 | Hypopituitarism | 1.403 |
| 90 | Retinitis pigmentosa | 1.376 |
| 28 | Systemic amyloidosis | 1.316 |
| 15 | Inclusion body myositis | 1.286 |
| 84 | Sarcoidosis | 1.282 |
| 97 | Ulcerative colitis | 1.223 |
| 4 | Primary lateral sclerosis | 1.015 |
| 254 | Porphyria | 1.015 |
| 281 | Klippel-Trenaunay-Weber syndrome | 1.000 |
| 317 | Trifunctional protein deficiency | 1.000 |
| 137 | Focal cortical dysplasia | 1.000 |
| 192 | Cockayne syndrome | 1.000 |
| 277 | Lymphangiomatosis | 1.000 |