DR info

Clinical trials : 62 / Drugs : 93 - (DrugBank : 30) / Drug target genes : 30 - Drug target pathways : 144

Fanconi anemia and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
285	Fanconi anemia	-
60	Aplastic anemia	24.679
65	Primary immunodeficiency	21.991
46	Malignant rheumatoid arthritis	21.396
49	Systemic lupus erythematosus	18.716
13	Multiple sclerosis/Neuromyelitis optica	18.097
284	Diamond-Blackfan anemia	16.691
96	Crohn disease	15.488
51	Scleroderma	14.513
19	Lysosomal storage disease	13.952
53	Sjogren syndrome	13.156
283	Acquired pure red cell aplasia	12.341
164	Oculocutaneous albinism	12.047
62	Paroxysmal nocturnal hemoglobinuria	11.511
45	Eosinophilic granulomatosis with Polyangiitis	10.954
41	Giant cell arteritis	10.909
55	Relapsing polychondritis	10.419
11	Myasthenia gravis	10.000
85	Idiopathic interstitial pneumonia	9.740
97	Ulcerative colitis	9.369
42	Polyarteritis nodosa	9.317
50	Dermatomyositis	8.711
93	Primary biliary cholangitis	8.370
2	Amyotrophic lateral sclerosis	8.154
95	Autoimmune hepatitis	8.067
286	Hereditary sideroblastic anemia	8.000
35	Pemphigus	7.517
64	Thrombotic thrombocytopenic purpura	7.500
162	Pemphigoid	7.418
222	Primary nephrotic syndrome	7.203
40	Takayasu arteritis	7.099
61	Autoimmune hemolytic anemia	7.099
28	Systemic amyloidosis	7.084
38	Stevens-Johnson syndrome	6.480
107	Juvenile idiopathic arthritis	6.462
39	Toxic epidermal necrolysis	6.400
20	Adrenoleukodystrophy	6.364
228	Bronchiolitis obliterans	6.356
326	Osteopetrosis	6.244
56	Behcet disease	6.162
234	Peroxisomal disease (except Adrenoleukodystrophy)	6.044
151	Rasmussen encephalitis	6.000
63	Idiopathic thrombocytopenic purpura	5.736
299	Cystic fibrosis	5.700
36	Epidermolysis bullosa	5.597
113	Muscular dystrophy	5.332
224	Purpura nephritis	5.262
6	Parkinson disease	5.260
66	IgA nephropathy	5.238
302	Leber hereditary optic neuropathy	5.000
160	Congenital ichthyosis	4.741
226	Interstitial cystitis with Hunners ulcer	4.375
44	Wegener granulomatosis	4.368
43	Microscopic polyangiitis	4.317
26	HTLV-1-associated myelopathy	4.192
84	Sarcoidosis	4.146
300	IgG4-related disease	4.138
269	Pyogenic arthritis	4.138
158	Tuberous sclerosis	3.474
271	Ankylosing spondylitis	3.278
86	Pulmonary arterial hypertension	3.267
227	Osler disease	3.267
274	Osteogenesis Imperfecta	3.257
331	Idiopathic multicentric castleman disease	2.845
270	Chronic recurrent multifocal osteomyelitis	2.844
83	Addison disease	2.844
94	Primary sclerosing cholangitis	2.716
77	Growth hormone secreting pituitary adenoma	2.000
16	Crow-Fukase syndrome	1.920
58	Hypertrophic cardiomyopathy	1.800
90	Retinitis pigmentosa	1.788
81	Congenital adrenal hyperplasia	1.689
76	Pituitary gonadotropin secretion hyperthyroidism	1.650
256	Muscle glycogenosis	1.505
25	Progressive multifocal leukoencephalopathy	1.457
229	Autoimmune pulmonary alveolar proteinosis	1.378
172	Hypophosphatasia	1.378
127	Frontotemporal lobar degeneration	1.354
34	Neurofibromatosis	1.073
15	Inclusion body myositis	1.036
52	Mixed connective tissue disease	1.000
220	Rapidly progressive glomerulonephritis	1.000
30	Distal myopathy	1.000
137	Focal cortical dysplasia	1.000
192	Cockayne syndrome	1.000
277	Lymphangiomatosis	1.000
281	Klippel-Trenaunay-Weber syndrome	1.000