DR info

Clinical trials : 71 / Drugs : 70 - (DrugBank : 39) / Drug target genes : 35 - Drug target pathways : 60

Biliary atresia and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
296	Biliary atresia	-
6	Parkinson disease	38.150
13	Multiple sclerosis/Neuromyelitis optica	36.224
84	Sarcoidosis	23.659
5	Progressive supranuclear palsy	18.162
22	Moyamoya disease	16.825
98	Eosinophilic gastrointestinal disease	16.789
152	PCDH19 related syndrome	16.000
2	Amyotrophic lateral sclerosis	15.504
46	Malignant rheumatoid arthritis	15.390
158	Tuberous sclerosis	15.238
17	Multiple system atrophy	14.811
96	Crohn disease	14.400
18	Spinocerebellar degeneration	13.827
205	Fragile X syndrome related disease	13.615
70	Spinal stenosis	13.364
201	Angelman syndrome	13.188
145	West syndrome	13.082
156	Rett syndrome	12.855
231	Alpha-1-antitrypsin deficiency	12.754
272	Fibrodysplasia ossificans progressiva	12.034
3	Spinal muscular atrophy	11.958
155	Acquired aphasia with convulsive disorder	11.378
36	Epidermolysis bullosa	11.167
298	Hereditary pancreatitis	10.868
97	Ulcerative colitis	10.443
21	Mitochondrial disease	10.248
193	Prader-Willi syndrome	9.948
206	Fragile X syndrome	9.752
8	Huntington disease	9.514
34	Neurofibromatosis	9.434
75	Cushing disease	9.323
140	Dorabe syndrome	9.126
144	Lennox-Gastaut syndrome	9.056
86	Pulmonary arterial hypertension	3.603
53	Sjogren syndrome	2.978
226	Interstitial cystitis with Hunners ulcer	2.812
11	Myasthenia gravis	2.592
299	Cystic fibrosis	2.475
19	Lysosomal storage disease	2.185
26	HTLV-1-associated myelopathy	2.178
297	Alagille syndrome	2.000
338	Progressive familial intrahepatic cholestasis	2.000
278	Huge lymphatic malformation with cervicofacial lesion	1.880
254	Porphyria	1.725
49	Systemic lupus erythematosus	1.452
300	IgG4-related disease	1.327
57	Idiopathic dilated cardiomyopathy	1.133
169	Menkes disease	1.133
170	Occipital horn syndrome	1.133
94	Primary sclerosing cholangitis	1.123
51	Scleroderma	1.076
251	Urea cycle disorder	1.044
167	Marfan syndrome	1.040
35	Pemphigus	1.018
324	Methylglutaconic aciduria	1.000
111	Congenital myopathy	1.000
52	Mixed connective tissue disease	1.000
220	Rapidly progressive glomerulonephritis	1.000
30	Distal myopathy	1.000