DR info

Clinical trials : 131 / Drugs : 139 - (DrugBank : 36) / Drug target genes : 33 - Drug target pathways : 125

Giant cell arteritis and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
41	Giant cell arteritis	-
46	Malignant rheumatoid arthritis	29.436
13	Multiple sclerosis/Neuromyelitis optica	22.589
50	Dermatomyositis	22.096
97	Ulcerative colitis	21.488
51	Scleroderma	20.280
96	Crohn disease	19.841
49	Systemic lupus erythematosus	18.833
40	Takayasu arteritis	17.065
65	Primary immunodeficiency	16.459
53	Sjogren syndrome	16.279
107	Juvenile idiopathic arthritis	15.152
84	Sarcoidosis	14.043
56	Behcet disease	13.909
269	Pyogenic arthritis	13.463
162	Pemphigoid	13.004
93	Primary biliary cholangitis	12.761
45	Eosinophilic granulomatosis with Polyangiitis	12.209
271	Ankylosing spondylitis	12.175
55	Relapsing polychondritis	12.000
42	Polyarteritis nodosa	11.538
85	Idiopathic interstitial pneumonia	11.306
285	Fanconi anemia	10.909
60	Aplastic anemia	10.898
19	Lysosomal storage disease	10.788
284	Diamond-Blackfan anemia	9.777
11	Myasthenia gravis	9.545
160	Congenital ichthyosis	9.455
164	Oculocutaneous albinism	9.258
44	Wegener granulomatosis	8.727
222	Primary nephrotic syndrome	7.789
228	Bronchiolitis obliterans	7.140
283	Acquired pure red cell aplasia	6.902
95	Autoimmune hepatitis	6.699
28	Systemic amyloidosis	6.673
43	Microscopic polyangiitis	6.662
6	Parkinson disease	6.540
62	Paroxysmal nocturnal hemoglobinuria	6.349
286	Hereditary sideroblastic anemia	6.311
151	Rasmussen encephalitis	6.000
38	Stevens-Johnson syndrome	5.172
66	IgA nephropathy	5.022
302	Leber hereditary optic neuropathy	5.000
39	Toxic epidermal necrolysis	4.994
326	Osteopetrosis	4.970
299	Cystic fibrosis	4.507
36	Epidermolysis bullosa	4.453
37	Generalised pustular psoriasis	4.364
274	Osteogenesis Imperfecta	4.242
113	Muscular dystrophy	4.212
2	Amyotrophic lateral sclerosis	4.136
226	Interstitial cystitis with Hunners ulcer	4.119
26	HTLV-1-associated myelopathy	4.005
64	Thrombotic thrombocytopenic purpura	3.898
331	Idiopathic multicentric castleman disease	3.503
20	Adrenoleukodystrophy	3.240
227	Osler disease	3.163
224	Purpura nephritis	3.055
61	Autoimmune hemolytic anemia	3.029
58	Hypertrophic cardiomyopathy	2.949
270	Chronic recurrent multifocal osteomyelitis	2.828
234	Peroxisomal disease (except Adrenoleukodystrophy)	2.525
35	Pemphigus	2.430
86	Pulmonary arterial hypertension	2.424
63	Idiopathic thrombocytopenic purpura	2.343
106	Cryopyrin-associated periodic syndrome	2.318
300	IgG4-related disease	2.172
256	Muscle glycogenosis	2.041
268	Nakajo-Nishimura syndrome	2.000
325	Hereditary autoinflammatory syndrome	2.000
158	Tuberous sclerosis	1.932
34	Neurofibromatosis	1.929
211	Hypoplastic left heart syndrome	1.909
16	Crow-Fukase syndrome	1.909
90	Retinitis pigmentosa	1.692
298	Hereditary pancreatitis	1.647
47	Buerger disease	1.636
266	Familial mediterranean fever	1.489
25	Progressive multifocal leukoencephalopathy	1.442
229	Autoimmune pulmonary alveolar proteinosis	1.374
172	Hypophosphatasia	1.374
235	Hypoparathyroidism	1.061
10	Charcot-Marie-Tooth disease	1.017
15	Inclusion body myositis	1.017
108	TNF receptor-associated periodic syndrome	1.000
267	Hyper-IgD syndrome	1.000
54	Adult still disease	1.000
52	Mixed connective tissue disease	1.000
220	Rapidly progressive glomerulonephritis	1.000
30	Distal myopathy	1.000