52. Mixed connective tissue disease Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 8 / Drugs : 7 - (DrugBank : 3) / Drug target gene : 1 - Drug target pathway : 1
Mixed connective tissue disease and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 52 | Mixed connective tissue disease | - |
| 36 | Epidermolysis bullosa | 1.000 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 1.000 |
| 6 | Parkinson disease | 1.000 |
| 63 | Idiopathic thrombocytopenic purpura | 1.000 |
| 94 | Primary sclerosing cholangitis | 1.000 |
| 17 | Multiple system atrophy | 1.000 |
| 19 | Lysosomal storage disease | 1.000 |
| 35 | Pemphigus | 1.000 |
| 46 | Malignant rheumatoid arthritis | 1.000 |
| 49 | Systemic lupus erythematosus | 1.000 |
| 51 | Scleroderma | 1.000 |
| 60 | Aplastic anemia | 1.000 |
| 61 | Autoimmune hemolytic anemia | 1.000 |
| 65 | Primary immunodeficiency | 1.000 |
| 66 | IgA nephropathy | 1.000 |
| 84 | Sarcoidosis | 1.000 |
| 85 | Idiopathic interstitial pneumonia | 1.000 |
| 86 | Pulmonary arterial hypertension | 1.000 |
| 96 | Crohn disease | 1.000 |
| 127 | Frontotemporal lobar degeneration | 1.000 |
| 222 | Primary nephrotic syndrome | 1.000 |
| 256 | Muscle glycogenosis | 1.000 |
| 283 | Acquired pure red cell aplasia | 1.000 |
| 285 | Fanconi anemia | 1.000 |
| 331 | Idiopathic multicentric castleman disease | 1.000 |
| 53 | Sjogren syndrome | 1.000 |
| 271 | Ankylosing spondylitis | 1.000 |
| 162 | Pemphigoid | 1.000 |
| 93 | Primary biliary cholangitis | 1.000 |
| 50 | Dermatomyositis | 1.000 |
| 56 | Behcet disease | 1.000 |
| 97 | Ulcerative colitis | 1.000 |
| 300 | IgG4-related disease | 1.000 |
| 296 | Biliary atresia | 1.000 |
| 41 | Giant cell arteritis | 1.000 |
| 42 | Polyarteritis nodosa | 1.000 |
| 43 | Microscopic polyangiitis | 1.000 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 1.000 |
| 55 | Relapsing polychondritis | 1.000 |
| 284 | Diamond-Blackfan anemia | 1.000 |
| 11 | Myasthenia gravis | 1.000 |
| 44 | Wegener granulomatosis | 1.000 |
| 288 | Autoimmune acquired coagulation factor deficiency | 1.000 |
| 274 | Osteogenesis Imperfecta | 1.000 |
| 14 | Chronic inflammatory demyelinating polyneuropathy | 1.000 |
| 83 | Addison disease | 1.000 |
| 64 | Thrombotic thrombocytopenic purpura | 1.000 |
| 229 | Autoimmune pulmonary alveolar proteinosis | 1.000 |