DR info

Clinical trials : 305 / Drugs : 325 - (DrugBank : 104) / Drug target genes : 58 - Drug target pathways : 188

Sjogren syndrome and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
53	Sjogren syndrome	-
46	Malignant rheumatoid arthritis	35.799
13	Multiple sclerosis/Neuromyelitis optica	29.318
49	Systemic lupus erythematosus	26.180
96	Crohn disease	23.645
65	Primary immunodeficiency	19.708
51	Scleroderma	18.809
97	Ulcerative colitis	18.071
107	Juvenile idiopathic arthritis	17.920
162	Pemphigoid	16.279
41	Giant cell arteritis	16.279
50	Dermatomyositis	16.030
11	Myasthenia gravis	15.253
40	Takayasu arteritis	14.609
226	Interstitial cystitis with Hunners ulcer	14.427
271	Ankylosing spondylitis	13.481
84	Sarcoidosis	13.372
2	Amyotrophic lateral sclerosis	13.346
60	Aplastic anemia	13.333
285	Fanconi anemia	13.156
93	Primary biliary cholangitis	12.118
55	Relapsing polychondritis	12.000
160	Congenital ichthyosis	11.681
38	Stevens-Johnson syndrome	11.676
269	Pyogenic arthritis	11.676
19	Lysosomal storage disease	10.962
44	Wegener granulomatosis	10.521
284	Diamond-Blackfan anemia	10.205
95	Autoimmune hepatitis	9.865
56	Behcet disease	9.697
36	Epidermolysis bullosa	9.329
39	Toxic epidermal necrolysis	9.256
45	Eosinophilic granulomatosis with Polyangiitis	8.873
26	HTLV-1-associated myelopathy	8.397
28	Systemic amyloidosis	8.280
42	Polyarteritis nodosa	8.036
62	Paroxysmal nocturnal hemoglobinuria	7.979
6	Parkinson disease	7.821
283	Acquired pure red cell aplasia	7.578
299	Cystic fibrosis	7.334
300	IgG4-related disease	7.273
61	Autoimmune hemolytic anemia	7.121
228	Bronchiolitis obliterans	6.983
164	Oculocutaneous albinism	6.868
113	Muscular dystrophy	6.864
222	Primary nephrotic syndrome	6.773
86	Pulmonary arterial hypertension	6.470
43	Microscopic polyangiitis	6.312
256	Muscle glycogenosis	6.250
286	Hereditary sideroblastic anemia	6.236
151	Rasmussen encephalitis	6.000
224	Purpura nephritis	5.989
66	IgA nephropathy	5.835
64	Thrombotic thrombocytopenic purpura	5.707
35	Pemphigus	5.537
63	Idiopathic thrombocytopenic purpura	5.120
85	Idiopathic interstitial pneumonia	5.039
302	Leber hereditary optic neuropathy	5.000
37	Generalised pustular psoriasis	4.860
326	Osteopetrosis	4.582
20	Adrenoleukodystrophy	4.552
234	Peroxisomal disease (except Adrenoleukodystrophy)	4.455
227	Osler disease	4.418
270	Chronic recurrent multifocal osteomyelitis	4.242
83	Addison disease	4.242
58	Hypertrophic cardiomyopathy	4.217
1	Spinal and bulbar muscular atrophy	3.862
94	Primary sclerosing cholangitis	3.142
98	Eosinophilic gastrointestinal disease	3.125
168	Ehlers-Danlos syndrome	2.980
296	Biliary atresia	2.978
274	Osteogenesis Imperfecta	2.945
156	Rett syndrome	2.881
90	Retinitis pigmentosa	2.855
298	Hereditary pancreatitis	2.751
10	Charcot-Marie-Tooth disease	2.521
331	Idiopathic multicentric castleman disease	2.270
34	Neurofibromatosis	2.251
231	Alpha-1-antitrypsin deficiency	2.113
158	Tuberous sclerosis	2.113
268	Nakajo-Nishimura syndrome	2.000
325	Hereditary autoinflammatory syndrome	2.000
127	Frontotemporal lobar degeneration	1.960
159	Xeroderma pigmentosum	1.865
114	Non-dystrophic myotonia syndrome	1.717
254	Porphyria	1.651
76	Pituitary gonadotropin secretion hyperthyroidism	1.582
70	Spinal stenosis	1.539
25	Progressive multifocal leukoencephalopathy	1.379
172	Hypophosphatasia	1.358
5	Progressive supranuclear palsy	1.148
235	Hypoparathyroidism	1.036
54	Adult still disease	1.000
52	Mixed connective tissue disease	1.000
220	Rapidly progressive glomerulonephritis	1.000
30	Distal myopathy	1.000